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DNA damage response in neurodevelopment and neuromaintenance

The FEBS journal, 2023-07, Vol.290 (13), p.3300-3310

2023

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Lysine Acetylation and Deacetylation in Brain Development and Neuropathies

Genomics, proteomics & bioinformatics, 2017-02, Vol.15 (1), p.19-36

2017

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Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes

Molecular cell, 2016-11, Vol.64 (3), p.580-592

2016

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

Genes & development, 2004-06, Vol.18 (11), p.1272-1282

2004

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HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

eLife, 2021-02, Vol.10

2021

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Cell-type, Dose, and Mutation-type Specificity Dictate Mutant p53 Functions In Vivo

Cancer cell, 2012-12, Vol.22 (6), p.751-764

2012

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Trrap-Dependent Histone Acetylation Specifically Regulates Cell-Cycle Gene Transcription to Control Neural Progenitor Fate Decisions

Cell stem cell, 2014-05, Vol.14 (5), p.632-643

2014

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The Essential Function of the MRN Complex in the Resolution of Endogenous Replication Intermediates

Cell reports (Cambridge), 2014-01, Vol.6 (1), p.182-195

2014

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Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2001-06, Vol.477 (1), p.97-110

2001

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Human Fanconi Anemia Monoubiquitination Pathway Promotes Homologous DNA Repair

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (4), p.1110-1115

2005

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The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis

Human molecular genetics, 2017-05, Vol.26 (9), p.1694-1705

2017

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Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

The EMBO journal, 2006-11, Vol.25 (23), p.5527-5538

2006

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Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling

Molecular biology of the cell, 2002-03, Vol.13 (3), p.978-988

2002

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Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

European journal of cancer (1990), 2007-09, Vol.43 (14), p.2124-2133

2007

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Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Cell reports (Cambridge), 2012-12, Vol.2 (6), p.1498-1504

2012

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Failure of Poly(ADP-Ribose) Polymerase Cleavage by Caspases Leads to Induction of Necrosis and Enhanced Apoptosis

Molecular and Cellular Biology, 1999-07, Vol.19 (7), p.5124-5133

1999

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Depletion of the 110-Kilodalton Isoform of Poly(ADP-Ribose) Glycohydrolase Increases Sensitivity to Genotoxic and Endotoxic Stress in Mice

Molecular and Cellular Biology, 2004-08, Vol.24 (16), p.7163-7178

2004

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Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase

Experimental cell research, 2007-03, Vol.313 (5), p.984-996

2007

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Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

Journal of cerebral blood flow and metabolism, 1997-11, Vol.17 (11), p.1143

1997

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Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

Current biology, 2001-08, Vol.11 (15), p.1192-1196

2001

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Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis

BBA - Reviews on Cancer, 2001-11, Vol.1552 (1), p.27-37

2001

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The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells

Carcinogenesis (New York), 2005-10, Vol.26 (10), p.1731-1740

2005

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PARP is important for genomic stability but dispensable in apoptosis

Genes & development, 1997-09, Vol.11 (18), p.2347-2358

1997

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Null Mutation of DNA Strand Break-Binding Molecule Poly(ADP-ribose) Polymerase Causes Medulloblastomas in p53 −/− Mice

The American journal of pathology, 2003, Vol.162 (1), p.343-352

2003

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Involvement of Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribosyl)ation in Regulation of Centrosome Function

Molecular and Cellular Biology, 2003-04, Vol.23 (7), p.2451-2462

2003

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DNA damage response in neurodevelopment and neuromaintenance

Lysine Acetylation and Deacetylation in Brain Development and Neuropathies

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes

Alkylating DNA damage stimulates a regulated form of necrotic cell death

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

Cell-type, Dose, and Mutation-type Specificity Dictate Mutant p53 Functions In Vivo

Trrap-Dependent Histone Acetylation Specifically Regulates Cell-Cycle Gene Transcription to Control Neural Progenitor Fate Decisions

The Essential Function of the MRN Complex in the Resolution of Endogenous Replication Intermediates

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

Human Fanconi Anemia Monoubiquitination Pathway Promotes Homologous DNA Repair

The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Failure of Poly(ADP-Ribose) Polymerase Cleavage by Caspases Leads to Induction of Necrosis and Enhanced Apoptosis

Depletion of the 110-Kilodalton Isoform of Poly(ADP-Ribose) Glycohydrolase Increases Sensitivity to Genotoxic and Endotoxic Stress in Mice

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis

The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells

PARP is important for genomic stability but dispensable in apoptosis

Null Mutation of DNA Strand Break-Binding Molecule Poly(ADP-ribose) Polymerase Causes Medulloblastomas in p53 −/− Mice

Involvement of Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribosyl)ation in Regulation of Centrosome Function

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