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1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapy

PloS one, 2010-12, Vol.5 (12), p.e15823-e15823

2010

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IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain—containing protein tyrosine phosphatase 1

Journal of allergy and clinical immunology, 2007-07, Vol.120 (1), p.76-83

2007

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12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells

Folia histochemica et cytobiologica, 2013-01, Vol.51 (1), p.11-17

2013

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IL-13 induces YY1 through the AKT pathway in lung fibroblasts

PloS one, 2015-03, Vol.10 (3), p.e0119039-e0119039

2015

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13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3

PloS one, 2013-06, Vol.8 (6), p.e65308

2013

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17‐β‐Estradiol‐mediated activation of extracellular‐signal regulated kinase, phosphatidylinositol 3‐kinase/protein kinase B‐Akt and N‐methyl‐d‐aspartate receptor phosphorylation in cortical synaptoneurosomes

Journal of neurochemistry, 2007-04, Vol.101 (1), p.232-240

2007

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17β-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro

Respiratory research, 2014-12, Vol.15, p.159-159

2014

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1α,25(OH)2D3-glycosides from Solanum glaucophyllum leaves extract induce myoblasts differentiation through p38 MAPK and AKT activation

Biology open, 2018, Vol.7 (5), p.bio033670-bio033670

2018

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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits growth factor withdrawal-induced apoptosis in the human mammary epithelial cell line, MCF-10A

Carcinogenesis (New York), 2000-05, Vol.21 (5), p.881-886

2000

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2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) Induces Apoptosis via Modulating E7 Expression and Inhibition of PI3K/Akt Pathway in SiHa Human Cervical Cancer Cells

Nutrition and cancer, 2012-01, Vol.64 (8), p.1236-1244

2012

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2-decenoic acid ethyl ester, a compound that elicits neurotrophin-like intracellular signals, facilitating functional recovery from cerebral infarction in mice

International journal of molecular sciences, 2012-04, Vol.13 (4), p.4968-4981

2012

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(2-Hydroxypropyl)-β-Cyclodextrin Is a New Angiogenic Molecule for Therapeutic Angiogenesis

PloS one, 2015-05, Vol.10 (5), p.e0125323-e0125323

2015

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l-2-Oxothiazolidine-4-Carboxylic Acid or [alpha]-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-[kappa]B (NF-[kappa]B), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)

International journal of molecular sciences, 2012-07, Vol.13 (7), p.7915

2012

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2-Phenylethylamine (PEA) Ameliorates Corticosterone-Induced Depression-Like Phenotype via the BDNF/TrkB/CREB Signaling Pathway

International journal of molecular sciences, 2020-11, Vol.21 (23), p.9103

2020

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2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-κB Pathways in RAW 264.7 Macrophage Cells

PloS one, 2017-01, Vol.12 (1), p.e0168945-e0168945

2017

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20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes

International journal of molecular medicine, 2015-05, Vol.35 (5), p.1388-1394

2015

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The 20KDa and 22KDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties

General and comparative endocrinology, 2017-07, Vol.248, p.49-54

2017

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24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation

Bioengineered, 2022-01, Vol.13 (1), p.155-163

2022

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3,5,4′-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial–mesenchymal transition

Toxicology and applied pharmacology, 2013-11, Vol.272 (3), p.746-756

2013

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3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner

Neoplasia (New York, N.Y.), 2012-08, Vol.14 (8), p.719-IN19

2012

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The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

PLoS biology, 2021-12, Vol.19 (12), p.e3001483

2021

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IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin

Journal of allergy and clinical immunology, 2012-11, Vol.130 (5), p.1159-1166.e6

2012

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5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-[gamma]-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability

Journal of neuroinflammation, 2012-02, Vol.9, p.34

2012

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A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.781

2021

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60kDa Lysophospholipase, a New Sgk1 Molecular Partner Involved in the Regulation of ENaC

Cellular physiology and biochemistry, 2010, Vol.26 (4-5), p.587-596

2010

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1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapy

IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain—containing protein tyrosine phosphatase 1

12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells

IL-13 induces YY1 through the AKT pathway in lung fibroblasts

13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3

17‐β‐Estradiol‐mediated activation of extracellular‐signal regulated kinase, phosphatidylinositol 3‐kinase/protein kinase B‐Akt and N‐methyl‐d‐aspartate receptor phosphorylation in cortical synaptoneurosomes

17β-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro

1α,25(OH)2D3-glycosides from Solanum glaucophyllum leaves extract induce myoblasts differentiation through p38 MAPK and AKT activation

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits growth factor withdrawal-induced apoptosis in the human mammary epithelial cell line, MCF-10A

2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) Induces Apoptosis via Modulating E7 Expression and Inhibition of PI3K/Akt Pathway in SiHa Human Cervical Cancer Cells

2-decenoic acid ethyl ester, a compound that elicits neurotrophin-like intracellular signals, facilitating functional recovery from cerebral infarction in mice

(2-Hydroxypropyl)-β-Cyclodextrin Is a New Angiogenic Molecule for Therapeutic Angiogenesis

l-2-Oxothiazolidine-4-Carboxylic Acid or [alpha]-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-[kappa]B (NF-[kappa]B), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)

2-Phenylethylamine (PEA) Ameliorates Corticosterone-Induced Depression-Like Phenotype via the BDNF/TrkB/CREB Signaling Pathway

2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-κB Pathways in RAW 264.7 Macrophage Cells

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes

The 20KDa and 22KDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties

24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation

3,5,4′-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial–mesenchymal transition

3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin

5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-[gamma]-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability

A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis

60kDa Lysophospholipase, a New Sgk1 Molecular Partner Involved in the Regulation of ENaC

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