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Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

Trends in neurosciences (Regular ed.), 2014-12, Vol.37 (12), p.721-732

2014

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Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau

Chemical science (Cambridge), 2019-07, Vol.1 (26), p.653-657

2019

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Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

The EMBO journal, 2011-11, Vol.30 (23), p.4825-4837

2011

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Caenorhabditis elegans models of tauopathy

The FASEB journal, 2017-12, Vol.31 (12), p.5137-5148

2017

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Development of Tau Aggregation Inhibitors for Alzheimer's Disease

Angewandte Chemie (International ed.), 2009-02, Vol.48 (10), p.1740-1752

2009

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Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant

The Journal of neuroscience, 2011-02, Vol.31 (7), p.2511-2525

2011

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The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments

Biochemistry (Easton), 2008-10, Vol.47 (40), p.10526-10539

2008

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Oligomer Formation of Tau Protein Hyperphosphorylated in Cells

The Journal of biological chemistry, 2014-12, Vol.289 (49), p.34389-34407

2014

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Folding of the Tau Protein on Microtubules

Angewandte Chemie (International ed.), 2015-08, Vol.54 (35), p.10347-10351

International ed. in English, 2015

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Mechanistic Basis of Phenothiazine-Driven Inhibition of Tau Aggregation

Angewandte Chemie (International ed.), 2013-03, Vol.52 (12), p.3511-3515

International ed. in English, 2013

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Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity

Human molecular genetics, 2012-08, Vol.21 (16), p.3587-3603

2012

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Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation

The Journal of biological chemistry, 2008-11, Vol.283 (46), p.32066-32076

2008

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fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (4), p.E313-E321

2013

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Structural Impact of Tau Phosphorylation at Threonine 231

Structure (London), 2015-08, Vol.23 (8), p.1448-1458

2015

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FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease

Analytical chemistry (Washington), 2016-04, Vol.88 (7), p.3704-3714

2016

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FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments

Molecular neurodegeneration, 2020-07, Vol.15 (1), p.1-39, Article 39

2020

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Structural polymorphism of 441-residue tau at single residue resolution

PLoS biology, 2009-02, Vol.7 (2), p.e34-e1000034

2009

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Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity

The Journal of biological chemistry, 2014-07, Vol.289 (29), p.20318-20332

2014

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Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy

International journal of molecular sciences, 2023-05, Vol.24 (11), p.9260

2023

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Anthraquinones Inhibit Tau Aggregation and Dissolve Alzheimer's Paired Helical Filaments in Vitro and in Cells

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3628-3635

2005

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Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model

Molecular neurodegeneration, 2016-04, Vol.11 (1), Article 33

2016

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Backbone assignment for minimal protein amounts of low structural homogeneity in the absence of deuteration

Chemical communications (Cambridge, England), 2016-03, Vol.52 (21), p.4002-4005

2016

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Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation

Neurobiology of disease, 2018-09, Vol.117, p.189-202

2018

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Structural Impact of Proline-Directed Pseudophosphorylation at AT8, AT100, and PHF1 Epitopes on 441-Residue Tau

Journal of the American Chemical Society, 2011-10, Vol.133 (40), p.15842-15845

2011

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Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors

Neurobiology of aging, 2013-05, Vol.34 (5), p.1343-1354

2013

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Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

Caenorhabditis elegans models of tauopathy

Development of Tau Aggregation Inhibitors for Alzheimer's Disease

Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant

The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments

Oligomer Formation of Tau Protein Hyperphosphorylated in Cells

Folding of the Tau Protein on Microtubules

Mechanistic Basis of Phenothiazine-Driven Inhibition of Tau Aggregation

Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity

Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation

fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush

Structural Impact of Tau Phosphorylation at Threonine 231

FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments

Structural polymorphism of 441-residue tau at single residue resolution

Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity

Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy

Anthraquinones Inhibit Tau Aggregation and Dissolve Alzheimer's Paired Helical Filaments in Vitro and in Cells

Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model

Backbone assignment for minimal protein amounts of low structural homogeneity in the absence of deuteration

Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation

Structural Impact of Proline-Directed Pseudophosphorylation at AT8, AT100, and PHF1 Epitopes on 441-Residue Tau

Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors

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