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Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

Nature reviews. Cancer, 2011-02, Vol.11 (2), p.111-121

Huff, Vicki

2011

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A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

PloS one, 2018-12, Vol.13 (12), p.e0208936-e0208936

2018

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Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

Genes chromosomes & cancer, 2008-06, Vol.47 (6), p.461-470

2008

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Children's Oncology Group's 2013 blueprint for research: Renal tumors

Pediatric blood & cancer, 2013-06, Vol.60 (6), p.994-1000

2013

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The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans

PLoS genetics, 2013-08, Vol.9 (8), p.e1003645-e1003645

2013

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Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

Neoplasia (New York, N.Y.), 2012-08, Vol.14 (8), p.742-IN21

2012

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Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

Neoplasia (New York, N.Y.), 2016-02, Vol.18 (2), p.71-81

2016

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Wilm’s tumor 1 promotes memory flexibility

Nature communications, 2019-08, Vol.10 (1), p.3756-18, Article 3756

2019

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Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

Experimental cell research, 2013-03, Vol.319 (5), p.612-622

2013

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Characterization of the Inflammatory Microenvironment and Identification of Potential Therapeutic Targets in Wilms Tumors

Translational oncology, 2014-08, Vol.7 (4), p.484-492

2014

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Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

Stem cell reports, 2014-07, Vol.3 (1), p.24-33

2014

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Familial Wilms tumor

American journal of medical genetics. Part C, Seminars in medical genetics, 2004-08, Vol.129C (1), p.29-34

2004

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Twenty-four new cases of WT1 germline mutations and review of the literature: Genotype/phenotype correlations for Wilms tumor development

American journal of medical genetics, 2004-06, Vol.127A (3), p.249-257

2004

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Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse

Differentiation (London), 2024-07, Vol.138, p.100791, Article 100791

2024

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Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

Journal of medical genetics, 2016-06, Vol.53 (6), p.385-388

2016

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A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28

PloS one, 2018-12, Vol.13 (12), p.e0208936

2018

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Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

The Journal of clinical investigation, 2011-01, Vol.121 (1), p.174-183

2011

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Wilms Tumor Genetics: A New, UnX-pected Twist to the Story

Cancer cell, 2007-02, Vol.11 (2), p.105-107

Huff, Vicki

2007

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Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3940-3952

2010

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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Nature communications, 2015-12, Vol.6 (1), p.10013, Article 10013

2015

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Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis

The Journal of pathology, 2013-05, Vol.230 (1), p.39-47

2013

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Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumor using whole genome sequencing

Journal of medical genetics, 2015-11, Vol.53 (6), p.385-388

2015

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Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation1

Neoplasia (New York, N.Y.), 2016-02, Vol.18 (2), p.71-81

2016

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Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

Children's Oncology Group's 2013 blueprint for research: Renal tumors

The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

Wilm’s tumor 1 promotes memory flexibility

Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

Characterization of the Inflammatory Microenvironment and Identification of Potential Therapeutic Targets in Wilms Tumors

Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

Familial Wilms tumor

Twenty-four new cases of WT1 germline mutations and review of the literature: Genotype/phenotype correlations for Wilms tumor development

Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse

Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children’s Oncology Group AREN18B5-Q

Wilms Tumor Genetics: A New, UnX-pected Twist to the Story

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis

Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumor using whole genome sequencing

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation1

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