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Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats

Toxicological sciences, 2015-08, Vol.146 (2), p.363-373

2015

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Morphine metabolism, transport and brain disposition

Metabolic brain disease, 2012-03, Vol.27 (1), p.1-5

2012

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Metabolism and disposition of [14C]tivantinib after oral administration to humans, dogs and rats

Xenobiotica, 2014-11, Vol.44 (11), p.996-1008

2014

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Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Journal of pharmacokinetics and pharmacodynamics, 2012-02, Vol.39 (1), p.67-86

2012

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Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.462

2015

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Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

Environmental toxicology and chemistry, 2009-03, Vol.28 (3), p.542-554

2009

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Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

Molecular pharmaceutics, 2009-08, Vol.6 (4), p.1190-1204

2009

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A translational platform PBPK model for antibody disposition in the brain

Journal of pharmacokinetics and pharmacodynamics, 2019-08, Vol.46 (4), p.319-338

2019

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Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 2: Subchronic dose

Environmental toxicology and chemistry, 2009-03, Vol.28 (3), p.555-567

2009

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PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy

International journal of pharmaceutics, 2011-06, Vol.412 (1), p.132-141

2011

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Development of a Two-Layered Sheet Formulation of 5-Fluorouracil for Application to Rat's Livers to Ensure Controlled Release and Local Drug Disposition

Chemical & pharmaceutical bulletin, 2023-04, Vol.71 (4), p.277-281, Article c22-00775

2023

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Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.205

2007

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Disposition of Phenolic and Sulfated Metabolites after Inhalation Exposure to 4‑Chlorobiphenyl (PCB3) in Female Rats

Chemical research in toxicology, 2014-08, Vol.27 (8), p.1411-1420

2014

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Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration

Journal of pharmacy and pharmacology, 2005-12, Vol.57 (12), p.1555-1563

2005

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.727

2013

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Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats

Biological and Pharmaceutical Bulletin, 2020/03/01, Vol.43(3), pp.384-392

Miyake, Taiji

2020

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Renal Disposition of Colistin in the Isolated Perfused Rat Kidney

Antimicrobial Agents and Chemotherapy, 2009-07, Vol.53 (7), p.2857-2864

2009

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Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides

Molecular nutrition & food research, 2016-05, Vol.60 (5), p.1006-1019

2016

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Metabolism of flavonoids via enteric recycling: role of intestinal disposition

The Journal of pharmacology and experimental therapeutics, 2003-03, Vol.304 (3), p.1228

2003

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Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats

Journal of pharmacy and pharmacology, 2022-02, Vol.74 (2), p.200-207

2022

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Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

European journal of clinical investigation, 2003-11, Vol.33 (s2), p.1-5

Kim, R. B.

2003

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Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

The Journal of pharmacology and experimental therapeutics, 2015-05, Vol.353 (2), p.415

2015

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Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent

Xenobiotica, 2015-12, Vol.45 (12), p.1105-1115

2015

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Effects of Probenecid on Hepatic and Renal Disposition of Hexadecanedioate, an Endogenous Substrate of Organic Anion Transporting Polypeptide 1B in Rats

Journal of pharmaceutical sciences, 2021-05, Vol.110 (5), p.2274-2284

2021

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Dual Physiologically Based Pharmacokinetic Model of Liposomal and Nonliposomal Amphotericin B Disposition

Pharmaceutical research, 2014-01, Vol.31 (1), p.35-45

2014

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Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats

Morphine metabolism, transport and brain disposition

Metabolism and disposition of [14C]tivantinib after oral administration to humans, dogs and rats

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

A translational platform PBPK model for antibody disposition in the brain

Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 2: Subchronic dose

PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy

Development of a Two-Layered Sheet Formulation of 5-Fluorouracil for Application to Rat's Livers to Ensure Controlled Release and Local Drug Disposition

Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction

Disposition of Phenolic and Sulfated Metabolites after Inhalation Exposure to 4‑Chlorobiphenyl (PCB3) in Female Rats

Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration

Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats

Renal Disposition of Colistin in the Isolated Perfused Rat Kidney

Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides

Metabolism of flavonoids via enteric recycling: role of intestinal disposition

Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

Preclinical metabolism and disposition of luseogliflozin, a novel antihyperglycemic agent

Effects of Probenecid on Hepatic and Renal Disposition of Hexadecanedioate, an Endogenous Substrate of Organic Anion Transporting Polypeptide 1B in Rats

Dual Physiologically Based Pharmacokinetic Model of Liposomal and Nonliposomal Amphotericin B Disposition

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Suchergebnisse filtern