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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Clinical pharmacokinetics, 2024-02, Vol.63 (2), p.241-253

2024

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Multiple Peaking Phenomena in Pharmacokinetic Disposition

Clinical pharmacokinetics, 2010-06, Vol.49 (6), p.351-377

2010

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The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ Transplantation

Clinical pharmacokinetics, 2014-02, Vol.53 (2), p.123-139

2014

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Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

Clinical pharmacokinetics, 2015-07, Vol.54 (7), p.709-735

2015

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Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

Clinical pharmacokinetics, 2016-05, Vol.55 (5), p.507-524

2016

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Antimicrobial therapy in critically ill patients : A review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

Clinical pharmacokinetics, 2005-01, Vol.44 (10), p.1009-1034

2005

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Cytochrome P450 3A: Ontogeny and drug disposition

Clinical pharmacokinetics, 1999-12, Vol.37 (6), p.485-505

1999

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Infliximab Treatment Does Not Lead to Full TNF-α Inhibition: A Target-Mediated Drug Disposition Model

Clinical pharmacokinetics, 2022, Vol.61 (1), p.143-154

2022

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Disposition of Drugs in Block Copolymer Micelle Delivery Systems: From Discovery to Recovery

Clinical pharmacokinetics, 2008-01, Vol.47 (10), p.619-634

2008

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Altered Drug Disposition Following Bariatric Surgery: A Research Challenge

Clinical pharmacokinetics, 2015-06, Vol.54 (6), p.573-579

2015

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Pharmacodynamic-Mediated Drug Disposition (PDMDD) Model of Daratumumab Monotherapy in Patients with Multiple Myeloma

Clinical pharmacokinetics, 2023-05, Vol.62 (5), p.761-777

2023

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The Influence of Underlying Disease on Rituximab Pharmacokinetics May be Explained by Target-Mediated Drug Disposition

Clinical pharmacokinetics, 2022-03, Vol.61 (3), p.423-437

2022

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Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I

Clinical pharmacokinetics, 2019-01, Vol.58 (1), p.101-113

2019

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Target-Mediated Drug Disposition Pharmacokinetic–Pharmacodynamic Model of Bosentan and Endothelin-1

Clinical pharmacokinetics, 2017-12, Vol.56 (12), p.1499-1511

2017

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A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in Children

Clinical pharmacokinetics, 2014-12, Vol.53 (12), p.1171-1182

2014

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Tramadol and O-Desmethyl Tramadol Clearance Maturation and Disposition in Humans: A Pooled Pharmacokinetic Study

Clinical pharmacokinetics, 2015-02, Vol.54 (2), p.167-178

2015

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Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients

Clinical pharmacokinetics, 2016-10, Vol.55 (10), p.1239-1250

2016

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Disposition Pathway-Dependent Approach for Predicting Organic Anion-Transporting Polypeptide-Mediated Drug–Drug Interactions

Clinical pharmacokinetics, 2013-06, Vol.52 (6), p.433-441

Hu, Zhe-Yi

2013

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Prediction of Drug Disposition in Diabetic Patients by Means of a Physiologically Based Pharmacokinetic Model

Clinical pharmacokinetics, 2015-02, Vol.54 (2), p.179-193

2015

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Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies

Clinical pharmacokinetics, 2017-10, Vol.56 (10), p.1155-1171

2017

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The hepatic sinusoid in aging and cirrhosis: Effects on hepatic substrate disposition and drug clearance

Clinical pharmacokinetics, 2005-01, Vol.44 (2), p.187-200

2005

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Physiologically Based Pharmacokinetic Modeling of Impaired Carboxylesterase-1 Activity: Effects on Oseltamivir Disposition

Clinical pharmacokinetics, 2014-09, Vol.53 (9), p.825-836

2014

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Prediction of Drug Disposition on the Basis of its Chemical Structure

Clinical pharmacokinetics, 2013-06, Vol.52 (6), p.415-431

Stepensky, David

2013

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The Role of Pharmacogenetics in Drug Disposition and Response of Oral Glucose-Lowering Drugs

Clinical pharmacokinetics, 2013-10, Vol.52 (10), p.833-854

2013

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Characterisation of the Clinical Pharmacokinetics of Actinomycin D and the Influence of ABCB1 Pharmacogenetic Variation on Actinomycin D Disposition in Children with Cancer

Clinical pharmacokinetics, 2014-08, Vol.53 (8), p.741-751

2014

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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Multiple Peaking Phenomena in Pharmacokinetic Disposition

The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ Transplantation

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

Antimicrobial therapy in critically ill patients : A review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

Cytochrome P450 3A: Ontogeny and drug disposition

Infliximab Treatment Does Not Lead to Full TNF-α Inhibition: A Target-Mediated Drug Disposition Model

Disposition of Drugs in Block Copolymer Micelle Delivery Systems: From Discovery to Recovery

Altered Drug Disposition Following Bariatric Surgery: A Research Challenge

Pharmacodynamic-Mediated Drug Disposition (PDMDD) Model of Daratumumab Monotherapy in Patients with Multiple Myeloma

The Influence of Underlying Disease on Rituximab Pharmacokinetics May be Explained by Target-Mediated Drug Disposition

Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I

Target-Mediated Drug Disposition Pharmacokinetic–Pharmacodynamic Model of Bosentan and Endothelin-1

A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in Children

Tramadol and O-Desmethyl Tramadol Clearance Maturation and Disposition in Humans: A Pooled Pharmacokinetic Study

Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients

Disposition Pathway-Dependent Approach for Predicting Organic Anion-Transporting Polypeptide-Mediated Drug–Drug Interactions

Prediction of Drug Disposition in Diabetic Patients by Means of a Physiologically Based Pharmacokinetic Model

Target-Mediated Drug Disposition Population Pharmacokinetics Model of Alirocumab in Healthy Volunteers and Patients: Pooled Analysis of Randomized Phase I/II/III Studies

The hepatic sinusoid in aging and cirrhosis: Effects on hepatic substrate disposition and drug clearance

Physiologically Based Pharmacokinetic Modeling of Impaired Carboxylesterase-1 Activity: Effects on Oseltamivir Disposition

Prediction of Drug Disposition on the Basis of its Chemical Structure

The Role of Pharmacogenetics in Drug Disposition and Response of Oral Glucose-Lowering Drugs

Characterisation of the Clinical Pharmacokinetics of Actinomycin D and the Influence of ABCB1 Pharmacogenetic Variation on Actinomycin D Disposition in Children with Cancer

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