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Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

Acta pharmacologica Sinica, 2022-02, Vol.43 (2), p.494-503

2022

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physiologically‐based pharmacokinetic model for disposition of 2,3,7,8‐TCDD in fathead minnow and medaka

Environmental toxicology and chemistry, 2014-05, Vol.33 (5), p.1064-1071

2014

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Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

Environmental toxicology and chemistry, 2009-03, Vol.28 (3), p.542-554

2009

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A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

CPT: pharmacometrics and systems pharmacology, 2023-03, Vol.12 (3), p.346-359

2023

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Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species

Acta pharmacologica Sinica, 2018-06, Vol.39 (6), p.1048-1063

2018

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Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Phytotherapy research, 2021-06, Vol.35 (6), p.3286-3297

2021

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Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 2: Subchronic dose

Environmental toxicology and chemistry, 2009-03, Vol.28 (3), p.555-567

2009

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Mechanistic pharmacokinetics and pharmacodynamics of GalNAc-siRNA: Translational model involving competitive receptor-mediated disposition and RISC-dependent gene silencing applied to givosiran

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.176-190

2024

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Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration

Journal of pharmacy and pharmacology, 2005-12, Vol.57 (12), p.1555-1563

2005

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Confocal Imaging with a Fluorescent Bile Acid Analogue Closely Mimicking Hepatic Taurocholate Disposition

Journal of pharmaceutical sciences, 2014-06, Vol.103 (6), p.1872-1881

2014

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Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides

Molecular nutrition & food research, 2016-05, Vol.60 (5), p.1006-1019

2016

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Disposition of ON 01210.Na (Ex-RAD(R)), a Novel Radioprotectant, in the Isolated Perfused Rat Liver: Probing Metabolic Inhibition to Increase Systemic Exposure

Journal of pharmaceutical sciences, 2013-02, Vol.102 (2), p.732-740

2013

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Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats

Journal of pharmacy and pharmacology, 2022-02, Vol.74 (2), p.200-207

2022

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Preclinical metabolism and the disposition of vornorexant/TS‐142, a novel dual orexin 1/2 receptor antagonist for the treatment of insomnia

Pharmacology research & perspectives, 2024-04, Vol.12 (2), p.e1183-n/a

2024

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Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

European journal of clinical investigation, 2003-11, Vol.33 (s2), p.1-5

Kim, R. B.

2003

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Effects of Probenecid on Hepatic and Renal Disposition of Hexadecanedioate, an Endogenous Substrate of Organic Anion Transporting Polypeptide 1B in Rats

Journal of pharmaceutical sciences, 2021-05, Vol.110 (5), p.2274-2284

2021

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Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2524-2534

2017

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Effects of Uremic Toxins on Transport and Metabolism of Different Biopharmaceutics Drug Disposition Classification System Xenobiotics

Journal of pharmaceutical sciences, 2011-09, Vol.100 (9), p.3831-3842

2011

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Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting the Effects of Anti-FcRn Therapy on the Disposition of Endogenous IgG in Humans

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.714-724

2019

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Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver

Journal of pharmaceutical sciences, 2017-04, Vol.106 (4), p.1175-1182

2017

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Nonlinear disposition of lithium in rats and saturation of its tubular reabsorption by the sodium‐phosphate cotransporter as a cause

Biopharmaceutics & drug disposition, 2018-02, Vol.39 (2), p.83-87

2018

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The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs

Journal of pharmaceutical sciences, 2013-07, Vol.102 (7), p.2395-2408

2013

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Binding to dipeptidyl peptidase-4 determines the disposition of linagliptin (BI 1356) - investigations in DPP-4 deficient and wildtype rats

Biopharmaceutics & drug disposition, 2009-11, Vol.30 (8), p.422-436

2009

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Disposition and metabolism of the flavonoid chrysin in normal volunteers

British journal of clinical pharmacology, 2001-02, Vol.51 (2), p.143-146

2001

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Influence of vasomodulators and tumor transplantation on the disposition of 5‐fluorouracil after application to the liver surface in rats

Biopharmaceutics & drug disposition, 2017-09, Vol.38 (6), p.367-372

2017

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Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

physiologically‐based pharmacokinetic model for disposition of 2,3,7,8‐TCDD in fathead minnow and medaka

Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 1: Single dose

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species

Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Disposition of perfluorinated acid isomers in Sprague-Dawley rats; Part 2: Subchronic dose

Mechanistic pharmacokinetics and pharmacodynamics of GalNAc-siRNA: Translational model involving competitive receptor-mediated disposition and RISC-dependent gene silencing applied to givosiran

Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration

Confocal Imaging with a Fluorescent Bile Acid Analogue Closely Mimicking Hepatic Taurocholate Disposition

Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides

Disposition of ON 01210.Na (Ex-RAD(R)), a Novel Radioprotectant, in the Isolated Perfused Rat Liver: Probing Metabolic Inhibition to Increase Systemic Exposure

Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats

Preclinical metabolism and the disposition of vornorexant/TS‐142, a novel dual orexin 1/2 receptor antagonist for the treatment of insomnia

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

Effects of Probenecid on Hepatic and Renal Disposition of Hexadecanedioate, an Endogenous Substrate of Organic Anion Transporting Polypeptide 1B in Rats

Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban

Effects of Uremic Toxins on Transport and Metabolism of Different Biopharmaceutics Drug Disposition Classification System Xenobiotics

Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting the Effects of Anti-FcRn Therapy on the Disposition of Endogenous IgG in Humans

Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver

Nonlinear disposition of lithium in rats and saturation of its tubular reabsorption by the sodium‐phosphate cotransporter as a cause

The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs

Binding to dipeptidyl peptidase-4 determines the disposition of linagliptin (BI 1356) - investigations in DPP-4 deficient and wildtype rats

Disposition and metabolism of the flavonoid chrysin in normal volunteers

Influence of vasomodulators and tumor transplantation on the disposition of 5‐fluorouracil after application to the liver surface in rats

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