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Effect of Size on Solid Tumor Disposition of Protein Therapeutics

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1136-1145

2019

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Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

Xenobiotica, 2022-11, Vol.52 (9-11), p.973-985

2022

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Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.520

2014

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Morphine metabolism, transport and brain disposition

Metabolic brain disease, 2012-03, Vol.27 (1), p.1-5

2012

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Apical ABC Transporters and Cancer Chemotherapeutic Drug Disposition

ABC Transporters and Cancer, 2015, Vol.125, p.1-41

2015

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Detection and disposition of JWH-018 and JWH-073 in mice after exposure to “Magic Gold” smoke

Forensic science international, 2012-07, Vol.220 (1), p.91-96

2012

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Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

The Journal of pharmacology and experimental therapeutics, 2021-11, Vol.379 (2), p.134

2021

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P‑Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib

Molecular pharmaceutics, 2021-12, Vol.18 (12), p.4371-4384

2021

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Disposition of PCB 11 in Mice Following Acute Oral Exposure

Chemical research in toxicology, 2021-04, Vol.34 (4), p.988-991

2021

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Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Journal of pharmacokinetics and pharmacodynamics, 2012-02, Vol.39 (1), p.67-86

2012

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Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition

Journal of the American Society of Nephrology, 2016-10, Vol.27 (10), p.2997-3004

2016

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p53‐mediated regulation of bile acid disposition attenuates cholic acid‐induced cholestasis in mice

British journal of pharmacology, 2017-12, Vol.174 (23), p.4345-4361

2017

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The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition

Theranostics, 2019-01, Vol.9 (10), p.2754-2767

2019

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Intracellular disposition of chitosan nanoparticles in macrophages: intracellular uptake, exocytosis, and intercellular transport

International journal of nanomedicine, 2017-01, Vol.12, p.6383-6398

2017

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Synergistic interaction between genetics and disease on pravastatin disposition

Journal of hepatology, 2014-07, Vol.61 (1), p.139-147

2014

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Comparison of minipig, dog, monkey and human drug metabolism and disposition

Journal of pharmacological and toxicological methods, 2015-07, Vol.74, p.80-92

Dalgaard, Lars

2015

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Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

Molecular pharmaceutics, 2009-08, Vol.6 (4), p.1190-1204

2009

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Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

Archives of toxicology, 2017-07, Vol.91 (7), p.2643-2653

2017

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A translational platform PBPK model for antibody disposition in the brain

Journal of pharmacokinetics and pharmacodynamics, 2019-08, Vol.46 (4), p.319-338

2019

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The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs; insights from knockout and humanized mice

Drug resistance updates, 2016-07, Vol.27, p.72-88

2016

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Fifty Years of Aryl Hydrocarbon Receptor Research as Reflected in the Pages of Drug Metabolism and Disposition

Drug metabolism and disposition, 2023-06, Vol.51 (6), p.657-671

Riddick, David S

2023

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E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice

Drug metabolism and disposition, 2022-05, Vol.50 (5), p.591-599

2022

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Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP

Pharmaceutical research, 2016-03, Vol.33 (3), p.590-602

2016

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Sulfonation Disposition of Acacetin: In Vitro and in Vivo

Journal of agricultural and food chemistry, 2017-06, Vol.65 (24), p.4921-4931

2017

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PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy

International journal of pharmaceutics, 2011-06, Vol.412 (1), p.132-141

2011

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Effect of Size on Solid Tumor Disposition of Protein Therapeutics

Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition

Morphine metabolism, transport and brain disposition

Apical ABC Transporters and Cancer Chemotherapeutic Drug Disposition

Detection and disposition of JWH-018 and JWH-073 in mice after exposure to “Magic Gold” smoke

Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N -Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans

P‑Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib

Disposition of PCB 11 in Mice Following Acute Oral Exposure

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition

p53‐mediated regulation of bile acid disposition attenuates cholic acid‐induced cholestasis in mice

The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition

Intracellular disposition of chitosan nanoparticles in macrophages: intracellular uptake, exocytosis, and intercellular transport

Synergistic interaction between genetics and disease on pravastatin disposition

Comparison of minipig, dog, monkey and human drug metabolism and disposition

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

A translational platform PBPK model for antibody disposition in the brain

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs; insights from knockout and humanized mice

Fifty Years of Aryl Hydrocarbon Receptor Research as Reflected in the Pages of Drug Metabolism and Disposition

E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice

Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP

Sulfonation Disposition of Acacetin: In Vitro and in Vivo

PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy

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