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Optimization of isochromanone based urotensin II receptor agonists

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (13), p.4844-4854

2010

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Isochromanone-based urotensin-II receptor agonists

Bioorganic & medicinal chemistry, 2005-04, Vol.13 (8), p.3057-3068

2005

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Novel and potent small-molecule urotensin II receptor agonists

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (13), p.4657-4665

2009

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Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin

Journal of medicinal chemistry, 1990-10, Vol.33 (10), p.2925-2929

1990

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Phenyl-substituted analogs of oxotremorine as muscarinic antagonists

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.285-294

1992

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Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

Tetrahedron letters, 1991-09, Vol.32 (40), p.5625-5628

1991

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3-Lithioquinuclidin-2-ene: A novel intermediate for the synthesis of muscarinic agonists and antagonists

Bioorganic & medicinal chemistry letters, 1994-12, Vol.4 (24), p.2837-2840

1994

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A 3-D model for 5-HT1A-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin

Journal of medicinal chemistry, 1991-02, Vol.34 (2), p.497-510

1991

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Ligand-controlled palladium-catalyzed intramolecular reactions of phenyl-substituted prostaglandin F2 α analogues

Tetrahedron, 1995-08, Vol.51 (33), p.9139-9154

1995

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(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist

Journal of medicinal chemistry, 1990-06, Vol.33 (6), p.1541-1544

1990

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Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors

Bioorganic & medicinal chemistry letters, 1996-02, Vol.6 (4), p.415-420

1996

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Stereoisomers of 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine: Preparation and muscarinic receptor affinities

Chirality (New York, N.Y.), 1998, Vol.10 (9), p.813-820

1998

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beta.-Lactam analogs of oxotremorine. 3- and 4-Methyl-substituted 2-azetidinones

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.580-584

1990

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Novel L-Phe-Gly mimetics

Tetrahedron letters, 1992-07, Vol.33 (31), p.4487-4490

1992

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Chiral discrimination of complexes between benzyloxycarbonylglycyl- l-proline and 4-hydroxy-2-dipropylaminoindan in ion-pair chromatography : A molecular mechanics study

Journal of Chromatography A, 1994-04, Vol.666 (1), p.527-534

1994

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The formation of 3-methyl-1a,7b-dihydro-1H-cycloprop[ c]isoquinoline from trans-N-[2-(2-acetylphenyl)cyclopropyl]-2-(trimethylsilyl)ethylcarbamate

Tetrahedron letters, 1994-05, Vol.35 (20), p.3417-3420

1994

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Palladium-catalyzed synthesis of C3-substituted 3-deoxymorphines

Bioorganic & medicinal chemistry letters, 1994-11, Vol.4 (21), p.2527-2532

1994

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Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions with 5-HT1A receptors in the brain

Journal of medicinal chemistry, 1989-04, Vol.32 (4), p.779-783

1989

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Stereoselectivity and generality of the palladium-catalysed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with Oppolzer's sultam

J. Chem. Soc., Perkin Trans. 1, 1994 (4), p.461-470

1994

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Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide

Journal of medicinal chemistry, 1992-08, Vol.35 (17), p.3270-3279

1992

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Stereoselective synthesis of methoxy substituted 1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolines

Tetrahedron, 1987, Vol.43 (22), p.5443-5450

1987

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Analogs of the muscarinic agent 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]: synthesis and pharmacology

Journal of medicinal chemistry, 1992-05, Vol.35 (9), p.1541-1550

1992

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Amide, urea, and carbamate analogs of the muscarinic agent [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]trimethylammonium chloride

Journal of medicinal chemistry, 1992-07, Vol.35 (15), p.2787-2798

1992

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Circular dichroism spectroscopy of 2-aminotetralins

Chirality (New York, N.Y.), 1995, Vol.7 (2), p.82-89

1995

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Topography and conformational preferences of 6,7,8,9-tetrahydro-1-hydroxy-N,N-dipropyl-5H-benzocyclohepten-6-ylamine. A rationale for the dopaminergic inactivity

Journal of medicinal chemistry, 1989-04, Vol.32 (4), p.765-774

1989

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Optimization of isochromanone based urotensin II receptor agonists

Isochromanone-based urotensin-II receptor agonists

Novel and potent small-molecule urotensin II receptor agonists

Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin

Phenyl-substituted analogs of oxotremorine as muscarinic antagonists

Stereoselective palladium-catalyzed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with oppolzer's sultam

3-Lithioquinuclidin-2-ene: A novel intermediate for the synthesis of muscarinic agonists and antagonists

A 3-D model for 5-HT1A-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin

Ligand-controlled palladium-catalyzed intramolecular reactions of phenyl-substituted prostaglandin F2 α analogues

(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist

Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors

Stereoisomers of 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine: Preparation and muscarinic receptor affinities

beta.-Lactam analogs of oxotremorine. 3- and 4-Methyl-substituted 2-azetidinones

Novel L-Phe-Gly mimetics

Chiral discrimination of complexes between benzyloxycarbonylglycyl- l-proline and 4-hydroxy-2-dipropylaminoindan in ion-pair chromatography : A molecular mechanics study

The formation of 3-methyl-1a,7b-dihydro-1H-cycloprop[ c]isoquinoline from trans-N-[2-(2-acetylphenyl)cyclopropyl]-2-(trimethylsilyl)ethylcarbamate

Palladium-catalyzed synthesis of C3-substituted 3-deoxymorphines

Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions with 5-HT1A receptors in the brain

Stereoselectivity and generality of the palladium-catalysed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with Oppolzer's sultam

Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide

Stereoselective synthesis of methoxy substituted 1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolines

Analogs of the muscarinic agent 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]: synthesis and pharmacology

Amide, urea, and carbamate analogs of the muscarinic agent [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]trimethylammonium chloride

Circular dichroism spectroscopy of 2-aminotetralins

Topography and conformational preferences of 6,7,8,9-tetrahydro-1-hydroxy-N,N-dipropyl-5H-benzocyclohepten-6-ylamine. A rationale for the dopaminergic inactivity

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