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The intracellular pharmacology of antiretroviral protease inhibitors

Journal of antimicrobial chemotherapy, 2004-12, Vol.54 (6), p.982-990

2004

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Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.816-824

2012

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Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

British journal of clinical pharmacology, 1997-08, Vol.44 (2), p.190-194

1997

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P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

Journal of antimicrobial chemotherapy, 2002-10, Vol.50 (4), p.583-588

2002

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Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy

HIV medicine, 2014-11, Vol.15 (10), p.604-610

2014

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A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy

Obstetrics and gynecology (New York. 1953), 2003-06, Vol.101 (6), p.1307-1311

2003

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Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

British journal of clinical pharmacology, 1998-02, Vol.45 (2), p.107-114

1998

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Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

HIV medicine, 2011-03, Vol.12 (3), p.166-173

2011

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Inhibition of the CYP3A4-mediated metabolism and p-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components

British journal of clinical pharmacology, 1999-10, Vol.48 (4), p.543-552

1999

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Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

Antimicrobial Agents and Chemotherapy, 1997-06, Vol.41 (6), p.1231-1236

1997

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Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry

Journal of immunological methods, 2008-12, Vol.339 (2), p.270-274

2008

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Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda

Journal of antimicrobial chemotherapy, 2015-12, Vol.70 (12), p.3317-3322

2015

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Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Journal of antimicrobial chemotherapy, 2003-09, Vol.52 (3), p.354-358

2003

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Theophylline metabolism in human liver microsomes: inhibition studies

The Journal of pharmacology and experimental therapeutics, 1996-03, Vol.276 (3), p.912

1996

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CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro

Xenobiotica, 2002, Vol.32 (1), p.1-17

2002

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Zidovudine Phosphorylation and Mitochondrial Toxicity in Vitro

Toxicology and applied pharmacology, 2001-11, Vol.177 (1), p.54-58

2001

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A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

Journal of immunological methods, 2003-03, Vol.274 (1), p.129-137

2003

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Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Biochemical journal, 1992-01, Vol.281 (2), p.359-368

1992

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Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation

Journal of antimicrobial chemotherapy, 2013-11, Vol.68 (11), p.2545-2549

2013

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Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients

AIDS research and human retroviruses, 2001-09, Vol.17 (14), p.1329-1332

2001

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Dexamethasone metabolism in vitro: Species differences

The Journal of steroid biochemistry and molecular biology, 1997-07, Vol.62 (4), p.345-352

1997

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Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo

Journal of immunological methods, 2002-04, Vol.262 (1), p.159-165

2002

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Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients

Antimicrobial Agents and Chemotherapy, 2002-01, Vol.46 (1), p.135-143

2002

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Influence of Prior Exposure to Zidovudine on Stavudine Phosphorylation In Vivo and Ex Vivo

Antimicrobial Agents and Chemotherapy, 2001-02, Vol.45 (2), p.577-582

2001

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Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

The Journal of pharmacology and experimental therapeutics, 1996-04, Vol.277 (1), p.105

1996

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The intracellular pharmacology of antiretroviral protease inhibitors

Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations

Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy

A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

Inhibition of the CYP3A4-mediated metabolism and p-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components

Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry

Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda

Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Theophylline metabolism in human liver microsomes: inhibition studies

CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro

Zidovudine Phosphorylation and Mitochondrial Toxicity in Vitro

A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation

Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients

Dexamethasone metabolism in vitro: Species differences

Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo

Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients

Influence of Prior Exposure to Zidovudine on Stavudine Phosphorylation In Vivo and Ex Vivo

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

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