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Preventing type 1 diabetes in childhood

Science (American Association for the Advancement of Science), 2021-07, Vol.373 (6554), p.506-510

2021

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Using de novo assembly to identify structural variation of eight complex immune system gene regions

PLoS computational biology, 2021-08, Vol.17 (8), p.e1009254-e1009254

2021

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SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile

Genome medicine, 2023-09, Vol.15 (1), p.1-12, Article 69

2023

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Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants

Scientific reports, 2022-08, Vol.12 (1), p.14137-14137, Article 14137

2022

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Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Frontiers in immunology, 2019-11, Vol.10, p.2606-2606

2019

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Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Wellcome open research, 2021, Vol.6, p.149

2021

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Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Wellcome open research, 2021-01, Vol.6, p.149

2021

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Tau depletion in human neurons mitigates Aβ-driven toxicity

Molecular psychiatry, 2024-07, Vol.29 (7), p.2009-2020

2024

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Transdermal Blood Sampling for C-Peptide Is a Minimally Invasive, Reliable Alternative to Venous Sampling in Children and Adults With Type 1 Diabetes

Diabetes care, 2024-02, Vol.47 (2), p.239-245

2024

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Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Diabetes (New York, N.Y.), 2022-07, Vol.71 (7), p.1591-1596

2022

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Cardiovascular stress biomarker assessment of middle-aged non-athlete marathon runners

European journal of preventive cardiology, 2019-02, Vol.26 (3), p.318-327

2019

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D'oh! Genes and Environment Cause Crohn's Disease

Cell, 2010-06, Vol.141 (7), p.1114-1116

Todd, John A.

2010

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Allele-specific methylation of type 1 diabetes susceptibility genes

Journal of autoimmunity, 2018-05, Vol.89, p.63-74

2018

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In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

Data in brief, 2017-06, Vol.12 (C), p.676-691

2017

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Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

Nature immunology, 2020-06, Vol.21 (6), p.695-695

2020

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Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

Nature immunology, 2019-03, Vol.20 (3), p.375-375

2019

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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Wellcome open research, 2017, Vol.2, p.28-28

2017

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Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD): a phase 2, multicentre, double-blind, randomized, placebo-controlled trial

Wellcome open research, 2020, Vol.5, p.49-49

2020

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Human IL-6RhiTIGIT− CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile

Clinical immunology (Orlando, Fla.), 2017-06, Vol.179, p.25-39

2017

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Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845

Diabetes (New York, N.Y.), 2015-09, Vol.64 (9), p.3334-3334

2015

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Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes

Advances in Immunology, 2008, Vol.100, p.151-175

2008

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Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach

British journal of clinical pharmacology, 2012-08, Vol.74 (2), p.376-380

2012

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Elevated Plasma Interleukin-6, Endothelin-1, and Matrix Metalloproteinase-9 in Heart Failure Patients are Associated With the Need for Advanced Therapies and Mortality

Journal of cardiac failure, 2015-08, Vol.21 (8), p.S90-S90

2015

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Preventing type 1 diabetes in childhood

Using de novo assembly to identify structural variation of eight complex immune system gene regions

SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile

Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants

Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Tau depletion in human neurons mitigates Aβ-driven toxicity

Transdermal Blood Sampling for C-Peptide Is a Minimally Invasive, Reliable Alternative to Venous Sampling in Children and Adults With Type 1 Diabetes

Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Cardiovascular stress biomarker assessment of middle-aged non-athlete marathon runners

D'oh! Genes and Environment Cause Crohn's Disease

Allele-specific methylation of type 1 diabetes susceptibility genes

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD): a phase 2, multicentre, double-blind, randomized, placebo-controlled trial

Human IL-6RhiTIGIT− CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile

Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845

Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach

Elevated Plasma Interleukin-6, Endothelin-1, and Matrix Metalloproteinase-9 in Heart Failure Patients are Associated With the Need for Advanced Therapies and Mortality

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