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AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia

Journal of molecular signaling, 2010-09, Vol.5 (1), p.15-15

2010

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AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells

Molecular cancer research, 2023-12, Vol.21 (12), p.1261-1273

2023

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Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines

Cancer cell international, 2002-03, Vol.2 (1), p.1-1, Article 1

2002

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Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

Leukemia research, 2015-11, Vol.39 (11), p.1246-1254

2015

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Stress-Induced AMPK Interactome Analysis Reveals Novel Protein-Protein Interactions Associated with Chromatin Remodeling and Transcription Machinery in Acute Lymphoblastic Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.5732-5732

2023

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Abstract 5116: Stress-induced AMPK interactome analysis reveals novel protein-protein interactions associated with chromatin remodeling in acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5116-5116

2024

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Abstract 1289: AICAR inhibits protein kinase D1 activity leading to epigenetic downregulation of immediate early genes via the NF-kB pathway in acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1289-1289

2019

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Characterization of a Highly Repetitive Sequence Conserved Among the North American Morone Species

Marine biotechnology (New York, N.Y.), 1999-03, Vol.1 (2), p.122-130

1999

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Abstract 4547: Rebalancing of Bcl-2 family proteins mediate the vulnerability of pevonedistat-treated acute lymphoblastic leukemia cells towards MEK/ERK pathway inhibition

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4547-4547

2016

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Abstract 4547: Rebalancing of Bcl-2 family proteins mediate the vulnerability of pevonedistat-treated acute lymphoblastic leukemia cells towards MEKERK pathway inhibition

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4547-4547

2016

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The NEDD8 Activating Enzyme Inhibitor Pevonedistat Induces ER Stress/UPR-Mediated Cell Death and Rebalances Homeostasis of Pro- and Anti-Apoptotic Proteins in Favor of Cell Death in Acute Lymphoblastic Leukemia Cells

Blood, 2015-12, Vol.126 (23), p.1327-1327

2015

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BCR-ABL+ Bp-ALL Exhibits Heightened Sensitivity to Simultaneous Induction of Energy and ER Stress Via Downregulation of Mcl-1 Expression

Blood, 2014-12, Vol.124 (21), p.916-916

2014

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The NEDD8 Conjugation Pathway Inhibitor MLN4924 Activates AMPK and Induces The ER Stress/UPR-Mediated Cell Death Pathway In Acute Lymphoblastic Leukemia

Blood, 2013-11, Vol.122 (21), p.1285-1285

2013

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The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose

Blood, 2012-11, Vol.120 (21), p.2439-2439

2012

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Abstract 4359: Folylpolyglutamate synthetase expression is transcriptionally regulated by chromatin remodeling and recruitment of a multiprotein corepressor complex associated to non-random fusions in ALL

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4359-4359

2010

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Abstract 2736: PIM2 is up-regulated in response to metformin-induced cell death triggered by ER stress/UPR in ALL lymphoblasts

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2736-2736

2012

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PIM2 Upregulation Leads to Physiological Buffering of Metformin-Induced Cell Death Mediated by ER Stress/UPR in Acute Lymphoblastic Leukemia

Blood, 2011-11, Vol.118 (21), p.3496-3496

2011

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Abstract 4991: Akt and AMPK modulate UPR activity and determine ER stress-induced cell death in response to 2-DG in ALL

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4991-4991

2012

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Abstract 605: A novel role for AMPK as a molecular switch regulating the activation of Akt and RAS signaling in acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.605-605

2011

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Histone Deacetylase Inhibitor Induces FPGS mRNA Expression in Childhood B-Precursor and T Acute Lymphoblastic Leukemia: Implication of Combination Therapy with Methotrexate To Enhance Cytotoxicity

Blood, 2007-11, Vol.110 (11), p.864-864

2007

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Histone Deacetylase Inhibitors Induce FPGS mRNA Expression and Intracellular Accumulation of Long-Chain Methotrexate Polyglutamates in Childhood Acute Lymphoblastic Leukemia: Implications for Combination Therapy

Blood, 2008-11, Vol.112 (11), p.2923-2923

2008

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Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts: e74420

PloS one, 2013-08, Vol.8 (8)

2013

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TEL/AML1 and E2A/PBX1 Tranlsocations Lead to Altered Folylpoly-γ-Glutamate Synthetase (FPGS) Expression in ALL

Blood, 2005-11, Vol.106 (11), p.539-539

2005

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Differences in Folylpoly-γ-Glutamate Synthetase (FPGS) Expression in Childhood ALL Result from Cell Lineage of Origin and Presence of Non-Random Translocations

Blood, 2004-11, Vol.104 (11), p.2087-2087

2004

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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside cells: implication for targeted therapy

Molecular cancer, 2007-07, Vol.6, p.46

2007

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AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia

AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells

Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

Stress-Induced AMPK Interactome Analysis Reveals Novel Protein-Protein Interactions Associated with Chromatin Remodeling and Transcription Machinery in Acute Lymphoblastic Leukemia

Abstract 5116: Stress-induced AMPK interactome analysis reveals novel protein-protein interactions associated with chromatin remodeling in acute lymphoblastic leukemia

Abstract 1289: AICAR inhibits protein kinase D1 activity leading to epigenetic downregulation of immediate early genes via the NF-kB pathway in acute lymphoblastic leukemia

Characterization of a Highly Repetitive Sequence Conserved Among the North American Morone Species

Abstract 4547: Rebalancing of Bcl-2 family proteins mediate the vulnerability of pevonedistat-treated acute lymphoblastic leukemia cells towards MEK/ERK pathway inhibition

Abstract 4547: Rebalancing of Bcl-2 family proteins mediate the vulnerability of pevonedistat-treated acute lymphoblastic leukemia cells towards MEKERK pathway inhibition

The NEDD8 Activating Enzyme Inhibitor Pevonedistat Induces ER Stress/UPR-Mediated Cell Death and Rebalances Homeostasis of Pro- and Anti-Apoptotic Proteins in Favor of Cell Death in Acute Lymphoblastic Leukemia Cells

BCR-ABL+ Bp-ALL Exhibits Heightened Sensitivity to Simultaneous Induction of Energy and ER Stress Via Downregulation of Mcl-1 Expression

The NEDD8 Conjugation Pathway Inhibitor MLN4924 Activates AMPK and Induces The ER Stress/UPR-Mediated Cell Death Pathway In Acute Lymphoblastic Leukemia

The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose

Abstract 4359: Folylpolyglutamate synthetase expression is transcriptionally regulated by chromatin remodeling and recruitment of a multiprotein corepressor complex associated to non-random fusions in ALL

Abstract 2736: PIM2 is up-regulated in response to metformin-induced cell death triggered by ER stress/UPR in ALL lymphoblasts

PIM2 Upregulation Leads to Physiological Buffering of Metformin-Induced Cell Death Mediated by ER Stress/UPR in Acute Lymphoblastic Leukemia

Abstract 4991: Akt and AMPK modulate UPR activity and determine ER stress-induced cell death in response to 2-DG in ALL

Abstract 605: A novel role for AMPK as a molecular switch regulating the activation of Akt and RAS signaling in acute lymphoblastic leukemia

Histone Deacetylase Inhibitor Induces FPGS mRNA Expression in Childhood B-Precursor and T Acute Lymphoblastic Leukemia: Implication of Combination Therapy with Methotrexate To Enhance Cytotoxicity

Histone Deacetylase Inhibitors Induce FPGS mRNA Expression and Intracellular Accumulation of Long-Chain Methotrexate Polyglutamates in Childhood Acute Lymphoblastic Leukemia: Implications for Combination Therapy

Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts: e74420

TEL/AML1 and E2A/PBX1 Tranlsocations Lead to Altered Folylpoly-γ-Glutamate Synthetase (FPGS) Expression in ALL

Differences in Folylpoly-γ-Glutamate Synthetase (FPGS) Expression in Childhood ALL Result from Cell Lineage of Origin and Presence of Non-Random Translocations

Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside cells: implication for targeted therapy

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