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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

The Journal of clinical investigation, 2003-11, Vol.112 (9), p.1300-1307

2003

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Erratum for Danhorn et al., “Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen Agrobacterium tumefaciens through the PhoR-PhoB Regulatory System”

Journal of bacteriology, 2024-08, Vol.206 (8)

2024

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Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139

ACS medicinal chemistry letters, 2011-04, Vol.2 (4), p.303-306

2011

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Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.10312-10332

2021

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Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2022-07, Vol.130 (7), p.458-476

2022

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Discovery of N -{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M 1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6386-6397

2010

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Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP(+) and Rotenone Toxicity

Frontiers in cellular neuroscience, 2016-06, Vol.10, p.164-164

2016

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Discovery of a potent and brain penetrant mGluRS positive allosteric modulator

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (12), p.3275-3278

2009

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Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr super(-) super(/) super(-) Mice

Antimicrobial agents and chemotherapy, 2007-10, Vol.51 (10), p.3677-3687

2007

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Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cjk-/- mice

Antimicrobial agents and chemotherapy, 2007, Vol.51 (10), p.3677-3687

2007

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Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an usp-type stress protein

Journal of bacteriology, 2005, Vol.188 (2), p.659-668

2005

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Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

Infection and immunity, 2005-08, Vol.73 (8), p.5290-5290

2005

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Antisense Silencing of the creA Gene inAspergillus nidulans

Applied and Environmental Microbiology, 2000-10, Vol.66 (10), p.4579

2000

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Targeting Quorum Sensing for Treatment of Chronic Bacterial Biofilm Infections

Laboratory medicine, 2002-04, Vol.33 (4), p.295-306

2002

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QUORUM SENSING IN BIOFILMS: GOSSIP IN SLIME CITY

Microbial Biofilms, 2004, p.118-140

2004

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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Erratum for Danhorn et al., “Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen Agrobacterium tumefaciens through the PhoR-PhoB Regulatory System”

Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139

Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

Discovery of N -{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M 1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP(+) and Rotenone Toxicity

Discovery of a potent and brain penetrant mGluRS positive allosteric modulator

Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr super(-) super(/) super(-) Mice

Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cjk-/- mice

Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an usp-type stress protein

Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

Antisense Silencing of the creA Gene inAspergillus nidulans

Targeting Quorum Sensing for Treatment of Chronic Bacterial Biofilm Infections

QUORUM SENSING IN BIOFILMS: GOSSIP IN SLIME CITY

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