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Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development

ACS medicinal chemistry letters, 2013-10, Vol.4 (10), p.964-968

2013

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Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

Nature structural & molecular biology, 2010-07, Vol.17 (7), p.808-814

2010

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Synthesis and biological activities of novel indole derivatives as potent and selective PPARγ modulators

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (4), p.1399-1404

2010

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Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Molecular cell, 2000-03, Vol.5 (3), p.545-555

2000

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Accounting for spin diffusion in the analysis of 2D NOE data

Journal of magnetic resonance (1969), 1986-03, Vol.67 (1), p.28-41

1986

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1-Methylphenanthro[3,4-b]thiophene: Determination of the tertiary structure in solution and in the crystalline state by NMR spectroscopy and X-ray diffraction

Journal of heterocyclic chemistry, 1985-03, Vol.22 (2), p.545-553

1985

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Heteronuclear three-dimensional NMR spectroscopy. Natural abundance carbon-13 chemical shift editing of 1H-1H COSY spectra

Journal of the American Chemical Society, 1989-01, Vol.111 (2), p.770-772

1989

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Pseudo-four-dimensional NMR by off-resonance decoupling: an approach for distinguishing coupled proton pairs by the frequencies of their attached heteronuclei

Journal of the American Chemical Society, 1990-06, Vol.112 (13), p.5370-5371

1990

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Total assignment of the carbon-13 NMR spectrum of the cembranoid diterpene eunicin through the use of two-dimensional proton-carbon chemical shift correlation

Journal of the American Chemical Society, 1984-03, Vol.106 (6), p.1823-1826

1984

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327-2327

2002

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327-2327

2002

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Benzo[b]phenanthro[4,3-d]thiophene: Spectral assignment by two-dimensional NMR methods and tertiary structure determination

Magnetic resonance in chemistry, 1986-12, Vol.24 (12), p.1039-1043

1986

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Application of isotope-filtered 2D NOE experiments in the conformational analysis of atrial natriuretic factor(7–23)

Journal of magnetic resonance (1969), 1987-09, Vol.74 (2), p.366-371

1987

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Chemistry of the phenoxathiins and isosterically related heterocycles. XIV. Total assignment of the 13C-Nmr spectrum of pyrrolo[3,2,1-kl]phenothiazine

Journal of heterocyclic chemistry, 1981-01, Vol.18 (1), p.155-161

1981

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Homonuclear two-dimensional J-resolved spectroscopy. The examination of resonances due to strong coupling in the two-dimensional J-spectrum of 1,6-diazathianthrene: The role of first order character in the position and intensity of resonances due to strong coupling

Journal of heterocyclic chemistry, 1983-01, Vol.20 (1), p.253-256

1983

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Chemistry of the phenoxathiins and isosterically related heterocycles. XXVII. Two-dimensional J-resolved spectra of 1,4,9-triazaphenoxathiin: The influence of frequency of the position and intensity of resonances due to strong coupling

Journal of heterocyclic chemistry, 1983-07, Vol.20 (4), p.1063-1075

1983

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Assignment of the 13C-NMR spectrum of phenanthro[4,3-A]dibenzothiophene through the utilization of two-dimensional relayed coherence transfer and double quantum coherence spectroscopy

Journal of heterocyclic chemistry, 1985-01, Vol.22 (1), p.219-223

1985

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The utilization of chemical shift and spin-lattice (T1) relaxation time data for the discrimination of isomeric indenoisoxazoles

Journal of heterocyclic chemistry, 1982-09, Vol.19 (5), p.1105-1107

1982

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Autocorrelated 13c-13c double quantum coherence two-dimensional nmr spectroscopy: Utilization of a modified version of the technique as an adjunct in the total assignment of the 1h- and 13c-nmr spectra of the mutagen phenanthro[3,4-b]thiophene

Journal of heterocyclic chemistry, 1983-11, Vol.20 (6), p.1661-1669

1983

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Combined application of auto-correlated (COSY) and homonuclear J-resolved two-dimensional NMR spectra for the assignment of congested, non-first order spectra of polycyclic aromatic systems. Assignment of the 1H-NMR spectrum of benzo[2,3]phenanthro-[4,5-bcd]thiophene and an investigation of long range 1H-1H spin-coupling constants

Journal of heterocyclic chemistry, 1984-01, Vol.21 (1), p.225-233

1984

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

Synthesis and biological activities of novel indole derivatives as potent and selective PPARγ modulators

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Accounting for spin diffusion in the analysis of 2D NOE data

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1 H -indol-5-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

1-Methylphenanthro[3,4-b]thiophene: Determination of the tertiary structure in solution and in the crystalline state by NMR spectroscopy and X-ray diffraction

Heteronuclear three-dimensional NMR spectroscopy. Natural abundance carbon-13 chemical shift editing of 1H-1H COSY spectra

Pseudo-four-dimensional NMR by off-resonance decoupling: an approach for distinguishing coupled proton pairs by the frequencies of their attached heteronuclei

Total assignment of the carbon-13 NMR spectrum of the cembranoid diterpene eunicin through the use of two-dimensional proton-carbon chemical shift correlation

Retraction

Retraction

Retraction

Benzo[b]phenanthro[4,3-d]thiophene: Spectral assignment by two-dimensional NMR methods and tertiary structure determination

Application of isotope-filtered 2D NOE experiments in the conformational analysis of atrial natriuretic factor(7–23)

Chemistry of the phenoxathiins and isosterically related heterocycles. XIV. Total assignment of the 13C-Nmr spectrum of pyrrolo[3,2,1-kl]phenothiazine

Homonuclear two-dimensional J-resolved spectroscopy. The examination of resonances due to strong coupling in the two-dimensional J-spectrum of 1,6-diazathianthrene: The role of first order character in the position and intensity of resonances due to strong coupling

Chemistry of the phenoxathiins and isosterically related heterocycles. XXVII. Two-dimensional J-resolved spectra of 1,4,9-triazaphenoxathiin: The influence of frequency of the position and intensity of resonances due to strong coupling

Assignment of the 13C-NMR spectrum of phenanthro[4,3-A]dibenzothiophene through the utilization of two-dimensional relayed coherence transfer and double quantum coherence spectroscopy

The utilization of chemical shift and spin-lattice (T1) relaxation time data for the discrimination of isomeric indenoisoxazoles

Autocorrelated 13c-13c double quantum coherence two-dimensional nmr spectroscopy: Utilization of a modified version of the technique as an adjunct in the total assignment of the 1h- and 13c-nmr spectra of the mutagen phenanthro[3,4-b]thiophene

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