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Novel distamycin analogues that block the cell cycle of African trypanosomes with high selectivity and potency

European journal of medicinal chemistry, 2020-03, Vol.189, p.112043, Article 112043

2020

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Alternative Thiol-Based Redox Systems

Antioxidants & redox signaling, 2018-02, Vol.28 (6), p.407-409

2018

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Organocatalytic Synthesis and Anti‐Trypanosomal Activity Evaluation of L‐Pentofuranose‐Mimetic Iminosugars

European journal of organic chemistry, 2022-09, Vol.2022 (34), p.n/a

2022

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Polyamine-Based Thiols in Trypanosomatids: Evolution, Protein Structural Adaptations, and Biological Functions

Antioxidants & redox signaling, 2018-02, Vol.28 (6), p.463-486

2018

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Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity

International journal for parasitology -- drugs and drug resistance, 2024-04, Vol.24, p.100529-100529, Article 100529

2024

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Nox2-derived superoxide radical is crucial to control acute Trypanosoma cruzi infection

Redox biology, 2021-10, Vol.46, p.102085-102085, Article 102085

2021

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The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

Scientific reports, 2018-09, Vol.8 (1), p.13716-14, Article 13716

2018

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Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania

Journal of enzyme inhibition and medicinal chemistry, 2020-12, Vol.35 (1), p.1345-1358

2020

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Evaluation of the Anti- Leishmania mexicana and - Trypanosoma brucei Activity and Mode of Action of 4,4'-(Arylmethylene)bis(3-methyl-1-phenyl-1 H -pyrazol-5-ol)

Biomedicines, 2022-08, Vol.10 (8), p.1913

2022

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CUTie2: The Attack of the Cyclic Nucleotide Sensor Clones

Frontiers in molecular biosciences, 2021-03, Vol.8, p.629773-629773

2021

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The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models

iScience, 2020-05, Vol.23 (5), p.101097-101097, Article 101097

2020

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Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system

EBioMedicine, 2021-01, Vol.63, p.103206-103206, Article 103206

2021

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A New Class of Thioredoxin‐Related Protein Able to Bind Iron–Sulfur Clusters

Antioxidants & redox signaling, 2016-02, Vol.24 (4), p.205-216

2016

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Synthesis of bicyclic 1,4-thiazepines as novel anti- Trypanosoma brucei brucei agents

MedChemComm, 2019-08, Vol.10 (8), p.1481-1487

2019

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A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites

Journal of coordination chemistry, 2015-08, Vol.68 (16), p.2923-2937

2015

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Valdiation of Trypanosoma brucei trypanothione synthetase as drug target

Free radical biology & medicine, 2004-05, Vol.36 (10), p.1289-1302

2004

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H-1, C-13 and N-15 resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei

Biomolecular NMR assignments, 2015-04, Vol.9 (1), p.143-146

2015

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Spatial-temporal detection of lipoperoxides with a genetically encoded biosensor targeted to different sub-cellular regions

Free radical biology & medicine, 2023-11, Vol.208, p.S24

2023

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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease

Frontiers in drug discovery, 2023-01, Vol.2

2023

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In vitro characterization of a fluorescent biosensor with specificity for organic peroxides

Free radical biology & medicine, 2023-05, Vol.201, p.29-29

2023

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Drugging the Undruggable ITrypanosoma brucei/I Monothiol Glutaredoxin 1

Molecules (Basel, Switzerland), 2023-01, Vol.28 (3)

2023

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The indole motif is essential for the antitrypanosomal activity of N.sup.5-substituted paullones

PloS one, 2023-11, Vol.18 (11), p.e0292946

2023

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Development of a genetically-encoded biosensor to monitor an H2S-related metabolite

Free radical biology & medicine, 2023-11, Vol.208, p.S114

2023

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Characterization of a fluorescent biosensor with specificity for organic peroxides

Free radical biology & medicine, 2023-11, Vol.208, p.S136

2023

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Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells

Journal of inorganic biochemistry, 2019-10, Vol.199, p.110779-110779, Article 110779

2019

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Novel distamycin analogues that block the cell cycle of African trypanosomes with high selectivity and potency

Alternative Thiol-Based Redox Systems

Organocatalytic Synthesis and Anti‐Trypanosomal Activity Evaluation of L‐Pentofuranose‐Mimetic Iminosugars

Polyamine-Based Thiols in Trypanosomatids: Evolution, Protein Structural Adaptations, and Biological Functions

Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity

Nox2-derived superoxide radical is crucial to control acute Trypanosoma cruzi infection

The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania

Evaluation of the Anti- Leishmania mexicana and - Trypanosoma brucei Activity and Mode of Action of 4,4'-(Arylmethylene)bis(3-methyl-1-phenyl-1 H -pyrazol-5-ol)

CUTie2: The Attack of the Cyclic Nucleotide Sensor Clones

The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models

Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system

A New Class of Thioredoxin‐Related Protein Able to Bind Iron–Sulfur Clusters

Synthesis of bicyclic 1,4-thiazepines as novel anti- Trypanosoma brucei brucei agents

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites

Valdiation of Trypanosoma brucei trypanothione synthetase as drug target

H-1, C-13 and N-15 resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei

Spatial-temporal detection of lipoperoxides with a genetically encoded biosensor targeted to different sub-cellular regions

Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease

In vitro characterization of a fluorescent biosensor with specificity for organic peroxides

Drugging the Undruggable ITrypanosoma brucei/I Monothiol Glutaredoxin 1

The indole motif is essential for the antitrypanosomal activity of N.sup.5-substituted paullones

Development of a genetically-encoded biosensor to monitor an H2S-related metabolite

Characterization of a fluorescent biosensor with specificity for organic peroxides

Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells

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