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Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

European journal of organic chemistry, 2012-08, Vol.2012 (22), p.4130-4139

2012

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(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Archives of biochemistry and biophysics, 2016-06, Vol.604, p.63-73

2016

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Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Archives of biochemistry and biophysics, 2022-11, Vol.730, p.109412-109412, Article 109412

2022

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Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas

European journal of medicinal chemistry, 2022-12, Vol.243, p.114744-114744, Article 114744

2022

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Abstract 6244: Design, synthesis, and structure-activity relationships of substituted pyrido[3,2- d ]pyrimidines as microtubule targeting agents and anti-cancer agents

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6244-6244

2023

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Novel pyrazolo4,3-dpyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents

Bioorganic & medicinal chemistry letters, 2021-06, Vol.41, p.127923

2021

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Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors

Computational biology and chemistry, 2019-06, Vol.80, p.512-523

2019

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Indolo[2,3-]benzazocines and indolo[2,3-]benzazonines and their copper() complexes as microtubule destabilizing agents

Dalton transactions : an international journal of inorganic chemistry, 2023-07, Vol.52 (29), p.9964-9982

2023

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Front Cover: 2‐Difluoromethoxy‐Substituted Estratriene Sulfamates: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Steroid Sulfatase Inhibition (ChemMedChem 23/2022)

ChemMedChem, 2022-12, Vol.17 (23), p.n/a

2022

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2-Difluoromethoxy-substituted Estratriene Sulfamates: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Steroid Sulfatase Inhibition

ChemMedChem, 2022-10, Vol.17 (23), p.e202200408-e202200408

2022

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Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia

European journal of medicinal chemistry, 2021-10, Vol.221, p.113532-113532, Article 113532

2021

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Abstract 4553: Substituted monocyclic pyrimidines as potent tubulin inhibitors that circumvent P-glycoprotein mediated resistance

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4553-4553

2015

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New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors

European journal of medicinal chemistry, 2018-05, Vol.152, p.283-297

2018

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Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents

European journal of medicinal chemistry, 2019-03, Vol.166, p.514-530

2019

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Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2- d ][1,2]oxazoles: A new class of antimitotic agents

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.C097-C097

2019

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Pyrrolo2',3':3,4cyclohepta1,2-d1,2oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.12023

2020

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Abstract 2477: Design, synthesis and biological evaluation of substituted monocyclic pyrimidines as potent microtubule targeting antitumor agents that circumvent Pgp and βIII-tubulin-mediated resistance

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2477-2477

2013

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Synthesis and Biological Evaluation of Novel EpothiloneB Side Chain Analogues

ChemMedChem, 2015-12, Vol.10 (12), p.1974

2015

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Identification of pyrrolo3',4':3,4cyclohepta1,2-d1,2oxazoles as promising new candidates for the treatment of lymphomas

European journal of medicinal chemistry, 2023-06, Vol.254, p.115372

2023

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Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analoguesElectronic supplementary information (ESI) available. CCDC 1062247. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5ob01882j

2015-12

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Synthesis of two fluorescent GTP[gamma]S molecules and their biological relevance

Nucleosides, nucleotides & nucleic acids, 2017-06, Vol.36 (6), p.379

2017

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Isolation and structure of halistatin 1 from the eastern Indian Ocean marine sponge Phakellia carteri

Journal of organic chemistry, 1993-04, Vol.58 (9), p.2538-2543

1993

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3‑Aroyl-1,4-diarylpyrroles Inhibit Chronic Myeloid Leukemia Cell Growth through an Interaction with Tubulin

ACS medicinal chemistry letters, 2017-05, Vol.8 (5), p.521-526

2017

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors

ACS medicinal chemistry letters, 2012-01, Vol.3 (1), p.5-9

2012

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Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas

Abstract 6244: Design, synthesis, and structure-activity relationships of substituted pyrido[3,2- d ]pyrimidines as microtubule targeting agents and anti-cancer agents

Novel pyrazolo4,3-dpyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents

Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors

Indolo[2,3-]benzazocines and indolo[2,3-]benzazonines and their copper() complexes as microtubule destabilizing agents

Front Cover: 2‐Difluoromethoxy‐Substituted Estratriene Sulfamates: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Steroid Sulfatase Inhibition (ChemMedChem 23/2022)

4‑(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)‑1H‑pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells

2-Difluoromethoxy-substituted Estratriene Sulfamates: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Steroid Sulfatase Inhibition

Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia

Abstract 4553: Substituted monocyclic pyrimidines as potent tubulin inhibitors that circumvent P-glycoprotein mediated resistance

New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors

Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents

Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2- d ][1,2]oxazoles: A new class of antimitotic agents

Pyrrolo2',3':3,4cyclohepta1,2-d1,2oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Abstract 2477: Design, synthesis and biological evaluation of substituted monocyclic pyrimidines as potent microtubule targeting antitumor agents that circumvent Pgp and βIII-tubulin-mediated resistance

Synthesis and Biological Evaluation of Novel EpothiloneB Side Chain Analogues

Identification of pyrrolo3',4':3,4cyclohepta1,2-d1,2oxazoles as promising new candidates for the treatment of lymphomas

Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analoguesElectronic supplementary information (ESI) available. CCDC 1062247. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5ob01882j

Synthesis of two fluorescent GTP[gamma]S molecules and their biological relevance

Isolation and structure of halistatin 1 from the eastern Indian Ocean marine sponge Phakellia carteri

3‑Aroyl-1,4-diarylpyrroles Inhibit Chronic Myeloid Leukemia Cell Growth through an Interaction with Tubulin

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors

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