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Phase I Study of Adenoviral Delivery of the HSV-tk Gene and Ganciclovir Administration in Patients with Recurrent Malignant Brain Tumors

Molecular therapy, 2000-02, Vol.1 (2), p.195-203

2000

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P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S2151-S2152

2017

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Phase I trial of gene-mediated cytotoxic immunotherapy in combination with chemoradiation for locally advanced pancreatic cancer

Journal of clinical oncology, 2011-02, Vol.29 (4_suppl), p.195-195

2011

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Phase I/II trial evaluating combined radiotherapy and in-situ gene therapy with or without hormonal therapy in the treatment of prostate cancer-an interim report on PSA response and biopsy data

International journal of radiation oncology, biology, physics, 2002-10, Vol.54 (2), p.138-138

2002

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Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer

Cancer gene therapy, 2002-05, Vol.9 (5), p.478-481

2002

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2188

International journal of radiation oncology, biology, physics, 2006-11, Vol.66 (3), p.S314

2006

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Five year follow up of a phase II study of cytotoxic immunotherapy combined with radiation in newly diagnosed prostate cancer

Journal of clinical oncology, 2006-06, Vol.24 (18_suppl), p.4635-4635

2006

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Radiographic and immunologic responses to adjuvant immunotherapy for malignant gliomas

Journal of clinical oncology, 2008-05, Vol.26 (15_suppl), p.2039-2039

2008

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2188: Long Term Biochemical Outcome of a Phase I-II Trial Evaluating Cytotoxic Immuno-Genetherapy in Combination With IMRT in Newly Diagnosed Prostate Cancer

International journal of radiation oncology, biology, physics, 2006, Vol.66 (3), p.S314-S314

2006

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IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2011-11, Vol.13 (suppl_3), p.iii34-iii40

2011

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Reporting adverse events in gene therapy studies

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2000-09, Vol.14 (3), p.141-145

2000

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2193

International journal of radiation oncology, biology, physics, 2006-11, Vol.66 (3), p.S316-S317

2006

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Adenovirus-mediated thymidine kinase gene therapy for recurrent ovarian cancer: Expression of coxsackie-adenovirus receptor and integrins αvβ3 and αvβ5

Journal of the Society for Gynecologic Investigation, 2002-06, Vol.9 (3), p.174-180

2002

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2193: Long-Term T Cell Activation Following Combined In Situ Gene Therapy and Intensity-Modulated Radiotherapy Compared to Gene Therapy as Mono-Therapy in Prostate Cancer Patients

International journal of radiation oncology, biology, physics, 2006, Vol.66 (3), p.S316-S317

2006

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Sustained Long-term Immune Responses Following In Situ Gene Therapy Combined with Radiotherapy and Hormonal Therapy in Prostate Cancer Patients

International journal of radiation oncology, biology, physics, 2005-10, Vol.63, p.S299-S300

2005

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PSA nadir and 24 month biopsy interim analysis of AdV-tk/Valacyclovir gene therapy in combination with radiotherapy vs radiotherapy alone for prostate cancer

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.4571-4571

2004

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PSA nadir and 24 month biopsy interim analysis of AdV-tk/Valacyclovir gene therapy in combination with radiotherapy vs radiotherapy alone for prostate cancer

Journal of clinical oncology, 2004-07, Vol.22 (14_suppl), p.4571-4571

2004

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Late toxicity of a phase I/II trial evaluating combined radiotherapy and in-situ gene-therapy with or without hormonal therapy in the treatment of prostate cancer

International journal of radiation oncology, biology, physics, 2003-10, Vol.57 (2), p.S275-S275

2003

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Sensitivity and reproducibility in adenoviral infectious titer determination

Nature medicine, 1997-07, Vol.3 (7), p.808-811

1997

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Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene: Gene therapy in urologic oncology

World journal of urology, 2000, Vol.18 (2), p.125-129

2000

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Phase I/II trial evaluating combined radiotherapy and in-situ gene-therapy with or without hormonal therapy in the treatment of prostate cancer - a preliminary report

International journal of radiation oncology, biology, physics, 2000, Vol.48 (3), p.171-172

2000

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Toxicological Comparison of E2a-Deleted and First-Generation Adenoviral Vectors Expressing alpha sub(1)-Antitrypsin after Systemic Delivery

Human gene therapy, 1998-07, Vol.9 (11), p.1587-1598

1998

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Histologic and immunohistochemical analysis of tissue response to adenovirus-mediated herpes simplex thymidine kinase gene therapy of ovarian cancer

International journal of gynecological cancer, 2002-01, Vol.12 (1), p.66-73

2002

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505 Murine metastatic and nonmetastatic models of retinoblastoma: evaluation of a gene therapy protocol

Journal of pediatric hematology/oncology, 1998-07, Vol.20 (4), p.367

1998

Volltextzugriff (PDF)

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

Neuro-oncology (Charlottesville, Va.), 2018-01, Vol.20 (2), p.225-235

2018

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Phase I Study of Adenoviral Delivery of the HSV-tk Gene and Ganciclovir Administration in Patients with Recurrent Malignant Brain Tumors

P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

Phase I trial of gene-mediated cytotoxic immunotherapy in combination with chemoradiation for locally advanced pancreatic cancer

Phase I/II trial evaluating combined radiotherapy and in-situ gene therapy with or without hormonal therapy in the treatment of prostate cancer-an interim report on PSA response and biopsy data

Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer

2188

Five year follow up of a phase II study of cytotoxic immunotherapy combined with radiation in newly diagnosed prostate cancer

Radiographic and immunologic responses to adjuvant immunotherapy for malignant gliomas

2188: Long Term Biochemical Outcome of a Phase I-II Trial Evaluating Cytotoxic Immuno-Genetherapy in Combination With IMRT in Newly Diagnosed Prostate Cancer

IMMUNOTHERAPY

Reporting adverse events in gene therapy studies

2193

Adenovirus-mediated thymidine kinase gene therapy for recurrent ovarian cancer: Expression of coxsackie-adenovirus receptor and integrins αvβ3 and αvβ5

2193: Long-Term T Cell Activation Following Combined In Situ Gene Therapy and Intensity-Modulated Radiotherapy Compared to Gene Therapy as Mono-Therapy in Prostate Cancer Patients

Sustained Long-term Immune Responses Following In Situ Gene Therapy Combined with Radiotherapy and Hormonal Therapy in Prostate Cancer Patients

PSA nadir and 24 month biopsy interim analysis of AdV-tk/Valacyclovir gene therapy in combination with radiotherapy vs radiotherapy alone for prostate cancer

PSA nadir and 24 month biopsy interim analysis of AdV-tk/Valacyclovir gene therapy in combination with radiotherapy vs radiotherapy alone for prostate cancer

Late toxicity of a phase I/II trial evaluating combined radiotherapy and in-situ gene-therapy with or without hormonal therapy in the treatment of prostate cancer

Sensitivity and reproducibility in adenoviral infectious titer determination

Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene: Gene therapy in urologic oncology

Phase I/II trial evaluating combined radiotherapy and in-situ gene-therapy with or without hormonal therapy in the treatment of prostate cancer - a preliminary report

Toxicological Comparison of E2a-Deleted and First-Generation Adenoviral Vectors Expressing alpha sub(1)-Antitrypsin after Systemic Delivery

Histologic and immunohistochemical analysis of tissue response to adenovirus-mediated herpes simplex thymidine kinase gene therapy of ovarian cancer

505 Murine metastatic and nonmetastatic models of retinoblastoma: evaluation of a gene therapy protocol

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

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