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Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

Pharmaceutical research, 2019-04, Vol.36 (4), p.51-14, Article 51

2019

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Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model

Journal of immunotoxicology, 2022-12, Vol.19 (1), p.1-7

2022

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Human neutrophil antigens: Nature, clinical significance and detection

International journal of immunogenetics, 2021-04, Vol.48 (2), p.145-156

2021

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Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment

Toxicological sciences, 2019-07, Vol.170 (1), p.210-222

2019

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The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors

Frontiers in immunology, 2017-02, Vol.8, p.162-162

2017

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Chemical allergen induced IgE production and type 2 cytokines expression: Elevated responses in ageing mice

Toxicology (Amsterdam), 2010, Vol.278 (3), p.361-361

2010

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Changes in the level of expression and frequency of B220 positive lymphocytes may discriminate more accurately between contact allergens and skin irritants

Toxicology (Amsterdam), 2011, Vol.290 (2), p.134-135

2011

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Prolonged exposure of mice to 2,4-dinitrochlorobenzene (DNCB) results in a Th1/Th17 cytokine fingerprint

Toxicology (Amsterdam), 2011, Vol.290 (2), p.105-105

2011

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Assessment of Protein Allergenicity Following Systemic Exposure in Mice: Relationship with Immunogenicity

Toxicology (Amsterdam), 2009-07, Vol.262 (1), p.1-1

2009

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The kinetics of 2,4-dinitrochlorobenzene (DNCB)- and trimellitic anhydride (TMA)-induced interleukin (IL)-17A and IL-17F production in murine skin

Toxicology (Amsterdam), 2010, Vol.278 (3), p.360-360

2010

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Differential Regulation of Epidermal Langerhans Cell Migration by Interleukins (IL)-1α and IL-1β during Irritant- and Allergen-Induced Cutaneous Immune Responses

Toxicology and applied pharmacology, 2002-07, Vol.182 (2), p.126-135

2002

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Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin‐1β

Immunology, 2002-04, Vol.105 (4), p.466-477

2002

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The effect of extracellular matrix (ECM) on 2,4-dinitrochlorobenzene (DNCB)-induced responses of the dendritic cell surrogate THP-1 cells

Toxicology (Amsterdam), 2010, Vol.278 (3), p.359-360

2010

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Factors affecting the development of food allergy

Proceedings of the Nutrition Society, 2002-11, Vol.61 (4), p.435-439

2002

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Differential Allergenicity of Human Lactoferrin: Role of Glycosylation

Toxicology (Amsterdam), 2008, Vol.253 (1), p.4-4

2008

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Chemical respiratory sensitizers: Activity in a non-standard local lymph node assay (LLNA)

Toxicology (Amsterdam), 2007-11, Vol.240 (3), p.186-187

2007

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Changes in granzyme B gene expression induced by chemical allergens

Toxicology (Amsterdam), 2007-11, Vol.240 (3), p.162-162

2007

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Chemical insult and toll-like receptor ligands: Synergistic effects on dendritic cells

Toxicology (Amsterdam), 2007, Vol.231 (2), p.115-116

2007

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Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods

Dermatitis, 2005, Vol.16 (4), p.157

2005

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Detection of Allergen-Specific IgE Antibody Responses

Journal of immunotoxicology, 2005, Vol.1 (3-4), p.189-199

2005

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Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-[alpha]

Immunology, 2015-01, Vol.144 (1), p.139

2015

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Skin sensitization induced L angerhans’ cell mobilization: variable requirements for tumour necrosis factor‐ α

Immunology, 2015-01, Vol.144 (1), p.139-148

2015

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Local Lymph Node Assays

Current Protocols in Toxicology, 2004-05, Vol.20 (1), p.18.2.1-18.2.12

2004

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"Omics" Technologies and the Immune System

Toxicology mechanisms and methods, 2006-01, Vol.16 (2-3), p.101-119

2006

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Impact of the route and characteristics of exposure on the acquisition of sensitisation to chemical allergens

Toxicology letters, 2006-09, Vol.164, p.S28-S29

Dearman, Rebecca J.

2006

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Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model

Human neutrophil antigens: Nature, clinical significance and detection

Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment

The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors

Chemical allergen induced IgE production and type 2 cytokines expression: Elevated responses in ageing mice

Changes in the level of expression and frequency of B220 positive lymphocytes may discriminate more accurately between contact allergens and skin irritants

Prolonged exposure of mice to 2,4-dinitrochlorobenzene (DNCB) results in a Th1/Th17 cytokine fingerprint

Assessment of Protein Allergenicity Following Systemic Exposure in Mice: Relationship with Immunogenicity

The kinetics of 2,4-dinitrochlorobenzene (DNCB)- and trimellitic anhydride (TMA)-induced interleukin (IL)-17A and IL-17F production in murine skin

Differential Regulation of Epidermal Langerhans Cell Migration by Interleukins (IL)-1α and IL-1β during Irritant- and Allergen-Induced Cutaneous Immune Responses

Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin‐1β

The effect of extracellular matrix (ECM) on 2,4-dinitrochlorobenzene (DNCB)-induced responses of the dendritic cell surrogate THP-1 cells

Factors affecting the development of food allergy

Differential Allergenicity of Human Lactoferrin: Role of Glycosylation

Chemical respiratory sensitizers: Activity in a non-standard local lymph node assay (LLNA)

Changes in granzyme B gene expression induced by chemical allergens

Chemical insult and toll-like receptor ligands: Synergistic effects on dendritic cells

Compilation of Historical Local Lymph Node Data for Evaluation of Skin Sensitization Alternative Methods

Detection of Allergen-Specific IgE Antibody Responses

Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-[alpha]

Skin sensitization induced L angerhans’ cell mobilization: variable requirements for tumour necrosis factor‐ α

Local Lymph Node Assays

"Omics" Technologies and the Immune System

Impact of the route and characteristics of exposure on the acquisition of sensitisation to chemical allergens

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