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Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

International journal of biological macromolecules, 2018-05, Vol.111, p.1146-1155

2018

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Identification of WP1066, an inhibitor of JAK2 and STAT3, as a KV1.3 potassium channel blocker

British journal of pharmacology, 2021-07, Vol.178 (13), p.2617-2631

2021

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Identification of WP1066, an inhibitor of JAK2 and STAT3, as a KV 1.3 potassium channel blocker

British journal of pharmacology, 2021-07, Vol.178 (13), p.2617-2631

2021

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Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1

The Journal of biological chemistry, 2015-05, Vol.290 (19), p.12195-12209

2015

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An ATP-dependent potassium channel blocker antagonizes morphine analgesia

European journal of pharmacology, 1990-09, Vol.186 (2-3), p.377-378

1990

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Potassium channel blockers in multiple sclerosis: Neuronal K sub(v) channels and effects of symptomatic treatment

Pharmacology & therapeutics (Oxford), 2006-07, Vol.111 (1), p.224-259

2006

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ATP-Sensitive Potassium Channel Openers and Blockers in the Cardiovascular System: Physiology, Pharmacology, and Clinical Effects

Seminars in cardiothoracic and vascular anesthesia, 1998-09, Vol.2 (3), p.243-255

1998

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Pharmacology of a cloned potassium channel from mouse brain (MK‐1) expressed in CHO cells: effects of blockers and an ‘nactivation peptide’

British journal of pharmacology, 1993-07, Vol.109 (3), p.725-735

1993

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Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers

Angewandte Chemie International Edition, 2019-10, Vol.58 (43), p.15421-15428

International ed. in English, 2019

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Pharmacology of Potassium Channels

1st Edition 2021, 2021

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The VRAC blocker DCPIB directly gates the BK channels and increases intracellular Ca2+ in melanoma and pancreatic duct adenocarcinoma cell lines

British journal of pharmacology, 2022-07, Vol.179 (13), p.3452-3469

2022

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β‐adrenergic Receptor Blocker ICI 118,551 Selectively Increases Intermediate‐Conductance Calcium‐Activated Potassium Channel (IKCa)‐Mediated Relaxations in Rat Main Mesenteric Artery

Basic & clinical pharmacology & toxicology, 2018-06, Vol.122 (6), p.570-576

2018

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Selective block of KATP channels: why the anti‐diabetic sulphonylureas and rosiglitazone have more in common than we thought

British journal of pharmacology, 2012-09, Vol.167 (1), p.23-25

Dart, Caroline

2012

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Potassium channel blocker prevents obesity

Nature reviews. Drug discovery, 2013-08, Vol.12 (8), p.580-577

Crunkhorn, Sarah

2013

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Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors

Frontiers in pharmacology, 2020-09, Vol.11, p.552211-552211

2020

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Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK

Peptides (New York, N.Y. : 1980), 2018-01, Vol.99, p.169-178

2018

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Treatment with senicapoc, a KCa3.1 channel blocker, alleviates hypoxaemia in a mouse model of acute respiratory distress syndrome

British journal of pharmacology, 2022-05, Vol.179 (10), p.2175-2192

2022

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Derivation of Highly Predictive 3D-QSAR Models for hERG Channel Blockers Based on the Quantum Artificial Neural Network Algorithm

Pharmaceuticals (Basel, Switzerland), 2023-10, Vol.16 (11), p.1509

2023

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5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis

Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3897

2021

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Methionine-isoleucine dichotomy at a key position in scorpion toxins inhibiting voltage-gated potassium channels

Toxicon (Oxford), 2023-08, Vol.231, p.107181-107181, Article 107181

2023

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GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries

Frontiers in pharmacology, 2021-03, Vol.12, p.613989-613989

2021

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Antidepressive effect of an inward rectifier K.sup.+ channel blocker peptide, tertiapin-RQ

PloS one, 2020-11, Vol.15 (11), p.e0233815

2020

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AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important Kv1.x (x = 1, 3, 6) Channels

Toxins, 2023-03, Vol.15 (3), p.229

2023

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Protective Effect of Peptide Calcium Channel Blocker Omega-Hexatoxin-Hv1a on Epithelial Cell during Ischemia–Reperfusion Injury

Pharmaceuticals (Basel, Switzerland), 2023-09, Vol.16 (9), p.1314

2023

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Facilitation of hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16261

Furutani, Kazuharu

2023

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Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

Identification of WP1066, an inhibitor of JAK2 and STAT3, as a KV1.3 potassium channel blocker

Identification of WP1066, an inhibitor of JAK2 and STAT3, as a KV 1.3 potassium channel blocker

Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1

An ATP-dependent potassium channel blocker antagonizes morphine analgesia

Potassium channel blockers in multiple sclerosis: Neuronal K sub(v) channels and effects of symptomatic treatment

ATP-Sensitive Potassium Channel Openers and Blockers in the Cardiovascular System: Physiology, Pharmacology, and Clinical Effects

Pharmacology of a cloned potassium channel from mouse brain (MK‐1) expressed in CHO cells: effects of blockers and an ‘nactivation peptide’

Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers

Pharmacology of Potassium Channels

The VRAC blocker DCPIB directly gates the BK channels and increases intracellular Ca2+ in melanoma and pancreatic duct adenocarcinoma cell lines

β‐adrenergic Receptor Blocker ICI 118,551 Selectively Increases Intermediate‐Conductance Calcium‐Activated Potassium Channel (IKCa)‐Mediated Relaxations in Rat Main Mesenteric Artery

Selective block of KATP channels: why the anti‐diabetic sulphonylureas and rosiglitazone have more in common than we thought

Potassium channel blocker prevents obesity

Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors

Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK

Treatment with senicapoc, a KCa3.1 channel blocker, alleviates hypoxaemia in a mouse model of acute respiratory distress syndrome

Derivation of Highly Predictive 3D-QSAR Models for hERG Channel Blockers Based on the Quantum Artificial Neural Network Algorithm

5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis

Methionine-isoleucine dichotomy at a key position in scorpion toxins inhibiting voltage-gated potassium channels

GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries

Antidepressive effect of an inward rectifier K.sup.+ channel blocker peptide, tertiapin-RQ

AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important Kv1.x (x = 1, 3, 6) Channels

Protective Effect of Peptide Calcium Channel Blocker Omega-Hexatoxin-Hv1a on Epithelial Cell during Ischemia–Reperfusion Injury

Facilitation of hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk

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