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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Pharmaceutical research, 2021-06, Vol.38 (6), p.1031-1039

2021

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Unstirred Water Layers and the Kinetics of Organic Cation Transport

Pharmaceutical research, 2015-09, Vol.32 (9), p.2937-2949

2015

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Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Pharmaceutical research, 2013-12, Vol.30 (12), p.3045-3058

2013

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Influence of anesthetic regimens on intestinal absorption in rats

Pharmaceutical research, 1993-06, Vol.10 (6), p.884-888

1993

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Characterization of the unstirred water layer in caco-2 cell monolayers using a novel diffusion apparatus

Pharmaceutical research, 1991-02, Vol.8 (2), p.222-227

1991

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The Asymmetry of the Unstirred Water Layer in Permeability Experiments

Pharmaceutical research, 2008-07, Vol.25 (7), p.1714-1722

2008

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Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

Pharmaceutical research, 2013-12, Vol.30 (12), p.2976-2992

2013

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Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

Pharmaceutical research, 2008-10, Vol.25 (10), p.2334-2344

2008

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Prediction of Oral Drug Absorption in Rats from In Vitro Data

Pharmaceutical research, 2023-02, Vol.40 (2), p.359-373

2023

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Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test

Pharmaceutical research, 2006-06, Vol.23 (6), p.1144-1156

2006

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In Situ Artificial Membrane Permeation Assay under Hydrodynamic Control: Permeability-pH Profiles of Warfarin and Verapamil

Pharmaceutical research, 2010-08, Vol.27 (8), p.1644-1658

2010

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Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate

Pharmaceutical research, 2020-05, Vol.37 (6), p.93-93, Article 93

2020

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Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults

Pharmaceutical research, 2023-02, Vol.40 (2), p.387-403

2023

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Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research

Pharmaceutical research, 2013-11, Vol.30 (11), p.2729-2756

2013

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Challenges of Using In Vitro Data for Modeling P-Glycoprotein Efflux in the Blood-Brain Barrier

Pharmaceutical research, 2014, Vol.31 (1), p.1-19

2014

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Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine

Pharmaceutical research, 2019-11, Vol.36 (11), p.1-11, Article 162

2019

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The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

Pharmaceutical research, 2020-05, Vol.37 (5), p.87-87, Article 87

2020

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UniORV, a New Multi-Unit Dosage Form, Improved Biopharmaceutical Properties of Tacrolimus in Rats and Humans

Pharmaceutical research, 2020-03, Vol.37 (3), p.64-64, Article 64

2020

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Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

Pharmaceutical research, 2012-06, Vol.29 (6), p.1485-1494

2012

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Lipophilicity and Its Relationship with Passive Drug Permeation

Pharmaceutical research, 2011-05, Vol.28 (5), p.962-977

2011

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Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells

Pharmaceutical research, 2001-08, Vol.18 (8), p.1138-1145

2001

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Interlaboratory Variability in Human Hepatocyte Intrinsic Clearance Values and Trends with Physicochemical Properties

Pharmaceutical research, 2019-08, Vol.36 (8), p.113-8, Article 113

2019

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The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives

Pharmaceutical research, 2022-08, Vol.39 (8), p.1681-1700

2022

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Importance of Considering Fed-State Gastrointestinal Physiology in Predicting the Reabsorption of Enterohepatic Circulation of Drugs

Pharmaceutical research, 2024-04, Vol.41 (4), p.673-685

2024

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Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat—Biophysical Model and Predictions Based on Caco-2

Pharmaceutical research, 2018-01, Vol.35 (1), p.2-23, Article 2

2018

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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Unstirred Water Layers and the Kinetics of Organic Cation Transport

Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Influence of anesthetic regimens on intestinal absorption in rats

Characterization of the unstirred water layer in caco-2 cell monolayers using a novel diffusion apparatus

The Asymmetry of the Unstirred Water Layer in Permeability Experiments

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

Prediction of Oral Drug Absorption in Rats from In Vitro Data

Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test

In Situ Artificial Membrane Permeation Assay under Hydrodynamic Control: Permeability-pH Profiles of Warfarin and Verapamil

Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate

Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults

Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research

Challenges of Using In Vitro Data for Modeling P-Glycoprotein Efflux in the Blood-Brain Barrier

Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine

The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

UniORV, a New Multi-Unit Dosage Form, Improved Biopharmaceutical Properties of Tacrolimus in Rats and Humans

Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

Lipophilicity and Its Relationship with Passive Drug Permeation

Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells

Interlaboratory Variability in Human Hepatocyte Intrinsic Clearance Values and Trends with Physicochemical Properties

The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives

Importance of Considering Fed-State Gastrointestinal Physiology in Predicting the Reabsorption of Enterohepatic Circulation of Drugs

Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat—Biophysical Model and Predictions Based on Caco-2

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