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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Nature communications, 2017-11, Vol.8 (1), p.1576-13, Article 1576

2017

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CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1976-1990

2017

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Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2745-2755.e4

2019

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Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates

PloS one, 2020-04, Vol.15 (4), p.e0231655

2020

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Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

Nature communications, 2016-07, Vol.7 (1), p.12175-15, Article 12175

2016

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Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells

European journal of immunology, 2014-09, Vol.44 (9), p.2692-2702

2014

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Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

Blood, 2008-11, Vol.112 (10), p.4158-4169

2008

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Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy

Journal of Virology, 2009-04, Vol.83 (7), p.3094-3103

2009

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The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Disease markers, 2010, Vol.29 (3-4), p.157-175

2010

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Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Diabetes (New York, N.Y.), 2004-08, Vol.53 (8), p.1979-1986

2004

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Phosphorylation of WASp is a key regulator of activity and stability in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (37), p.15738-15743

2009

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Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency

Journal of allergy and clinical immunology, 2013-03, Vol.131 (3), p.815-824.e2

2013

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Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

Blood, 2013-01, Vol.121 (1), p.72-84

2013

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Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

Molecular therapy, 2008-05, Vol.16 (5), p.836-844

2008

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Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Wellcome open research, 2018, Vol.3, p.84-84

2018

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Impaired neutrophil migration and phagocytosis in IRAK‐4 deficiency

British journal of haematology, 2009-10, Vol.147 (1), p.153-156

2009

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Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro

Journal of leukocyte biology, 2005-07, Vol.78 (1), p.70-79

2005

Volltextzugriff (PDF)

Su1794 TOLERABILITY, SAFETY, AND CLINICAL PHARMACOLOGY OF AZD7798, A DEPLETING ANTIBODY TARGETING CCR9

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-816-S-817

2024

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Sa2018 FIRST-TIME-IN-HUMAN VISUALISATION OF CCR9 EXPRESSION IN THE GUT BY POSITRON EMISSION TOMOGRAPHY

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-605-S-605

2024

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WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

Journal of leukocyte biology, 2016-05, Vol.99 (5), p.699-710

2016

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A randomised, double‐blind, placebo‐controlled study of the LAG‐3‐depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis

Alimentary pharmacology & therapeutics, 2023-08, Vol.58 (3), p.283-296

2023

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Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Blood, 2015-09, Vol.126 (13), p.1527-1535

2015

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Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

Rheumatology (Oxford, England), 2020-02, Vol.59 (2), p.335-343

2020

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Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

Immunobiology (1979), 2009-09, Vol.214 (9), p.778-790

2009

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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister

Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates

B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Phosphorylation of WASp is a key regulator of activity and stability in vivo

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Impaired neutrophil migration and phagocytosis in IRAK‐4 deficiency

Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro

Su1794 TOLERABILITY, SAFETY, AND CLINICAL PHARMACOLOGY OF AZD7798, A DEPLETING ANTIBODY TARGETING CCR9

Sa2018 FIRST-TIME-IN-HUMAN VISUALISATION OF CCR9 EXPRESSION IN THE GUT BY POSITRON EMISSION TOMOGRAPHY

WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

A randomised, double‐blind, placebo‐controlled study of the LAG‐3‐depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

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