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Emerging insights and challenges for understanding T cell function through the proteome

Frontiers in immunology, 2022-11, Vol.13, p.1028366-1028366

Solt, Laura A.

2022

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Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

Cancer cell, 2015-07, Vol.28 (1), p.42-56

2015

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A molecular switch regulating transcriptional repression and activation of PPARγ

Nature communications, 2020-02, Vol.11 (1), p.956-956, Article 956

2020

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Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

ACS chemical biology, 2016-07, Vol.11 (7), p.1795-1799

2016

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Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders

Nature communications, 2021-01, Vol.12 (1), p.1-18, Article 76

2021

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Editorial: Immunometabolism of T cells in skin infection, autoimmunity and cancer biology

Frontiers in immunology, 2023-06, Vol.14, p.1237386-1237386

2023

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Regulation of p53 stability and apoptosis by a ROR agonist

PloS one, 2012-04, Vol.7 (4), p.e34921

2012

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Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation

PLoS biology, 2018-06, Vol.16 (6), p.e2004663-e2004663

2018

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The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

Future medicinal chemistry, 2011-04, Vol.3 (5), p.623-638

2011

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Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

Journal of allergy and clinical immunology, 2008, Vol.122 (6), p.1169-1177.e16

2008

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Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation

PloS one, 2016-09, Vol.11 (9), p.e0162452-e0162452

2016

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REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2

Redox biology, 2022-05, Vol.51, p.102261-102261, Article 102261

2022

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Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells

Science immunology, 2019-10, Vol.4 (40)

2019

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Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

Current opinion in lipidology, 2010-06, Vol.21 (3), p.204-211

2010

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Nature (London), 2011-04, Vol.472 (7344), p.491-494

2011

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Action of RORs and their ligands in (patho)physiology

Trends in endocrinology and metabolism, 2012-12, Vol.23 (12), p.619-627

2012

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Pharmacological modulation and genetic deletion of REV-ERBα and REV-ERBβ regulates dendritic cell development

Biochemical and biophysical research communications, 2020-07, Vol.527 (4), p.1000-1007

2020

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Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

PloS one, 2016-05, Vol.11 (5), p.e0156367-e0156367

2016

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High throughput screening for compounds to the orphan nuclear receptor NR2F6

SLAS discovery, 2022-06, Vol.27 (4), p.242-248

2022

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REV-ERBα Regulates TH17 Cell Development and Autoimmunity

Cell reports (Cambridge), 2018-12, Vol.25 (13), p.3733-3749.e8

2018

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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Nature (London), 2012-03, Vol.485 (7396), p.62-68

2012

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Nuclear receptors and their selective pharmacologic modulators

Pharmacological reviews, 2013-04, Vol.65 (2), p.710

2013

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Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Nature medicine, 2013-08, Vol.19 (8), p.1039-1046

2013

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Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2019-01, Vol.15 (6), p.676

2019

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Emerging insights and challenges for understanding T cell function through the proteome

Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

A molecular switch regulating transcriptional repression and activation of PPARγ

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders

Editorial: Immunometabolism of T cells in skin infection, autoimmunity and cancer biology

Regulation of p53 stability and apoptosis by a ROR agonist

Perfect timing: circadian rhythms, sleep, and immunity - an NIH workshop summary

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation

The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation

REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2

Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells

Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Action of RORs and their ligands in (patho)physiology

Pharmacological modulation and genetic deletion of REV-ERBα and REV-ERBβ regulates dendritic cell development

Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

High throughput screening for compounds to the orphan nuclear receptor NR2F6

REV-ERBα Regulates TH17 Cell Development and Autoimmunity

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Nuclear receptors and their selective pharmacologic modulators

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α

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