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Novel Potent Selective Orally Active S1P5 Receptor Antagonists

ACS medicinal chemistry letters, 2021-03, Vol.12 (3), p.351-355

2021

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Isolation of Microglia and Analysis of Protein Expression by Flow Cytometry: Avoiding the Pitfall of Microglia Background Autofluorescence

Bio-protocol, 2021-07, Vol.11 (14), p.e4091-e4091

2021

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Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations

Scientific reports, 2021-05, Vol.11 (1), p.11154-11154, Article 11154

2021

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RNA-Seq and CyTOF immuno-profiling of regenerating lacrimal glands identifies a novel subset of cells expressing muscle-related proteins

PloS one, 2017-06, Vol.12 (6), p.e0179385-e0179385

2017

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Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

Frontiers in cellular neuroscience, 2020-12, Vol.14, p.592005-592005

2020

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Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis

Journal of neuroinflammation, 2022-12, Vol.19 (1), p.306-306, Article 306

2022

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Association between T follicular helper cells and T peripheral helper cells with B-cell biomarkers and disease activity in primary Sjögren syndrome

Rheumatic & musculoskeletal diseases open, 2021-03, Vol.7 (1), p.e001442

2021

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Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis

iScience, 2023-01, Vol.26 (1), p.105785-105785, Article 105785

2023

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The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

Nature immunology, 2008-05, Vol.9 (5), p.522-532

2008

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Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (48), p.14942-14947

2015

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Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation

Nature immunology, 2013-04, Vol.14 (4), p.404-412

2013

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Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors

Bioorganic & medicinal chemistry letters, 2022-03, Vol.60, p.128549-128549, Article 128549

2022

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Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model

The Journal of immunology (1950), 2022-04, Vol.208 (7), p.1566-1584

2022

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Corrigendum to “Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors” [Bioorg. Med. Chem. Lett. 60 (2022) 128549]

Bioorganic & medicinal chemistry letters, 2022-09, Vol.72, p.128856-128856, Article 128856

2022

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Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells

Nature immunology, 2013-01, Vol.14 (1), p.90-99

2013

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Identification of Novel CD4+ T Cell Subsets in the Target Tissue of Sjögren's Syndrome and Their Differential Regulation by the Lymphotoxin/LIGHT Signaling Axis

The Journal of immunology (1950), 2016-11, Vol.197 (10), p.3806-3819

2016

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Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.8122-8140

2024

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Osteopontin associates with brain T RM -cell transcriptome and compartmentalization in donors with and without multiple sclerosis

iScience, 2023-01, Vol.26 (1), p.105785

2023

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Multiplicity and plasticity of natural killer cell signaling pathways

Blood, 2006-03, Vol.107 (6), p.2364-2372

2006

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The proline-rich sequence of CD3 controls T cell antigen receptor expression on and signaling potency in preselection CD4 + CD8 + thymocytes

Nature immunology, 2008-05, Vol.9 (5), p.522-532

2008

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LAT signaling pathology: an “autoimmune” condition without T cell self-reactivity

Trends in immunology, 2010-07, Vol.31 (7), p.253-259

2010

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Consortium biology in immunology: the perspective from the Immunological Genome Project

Nature reviews. Immunology, 2012-10, Vol.12 (10), p.734-740

2012

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Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes

Seminars in immunopathology, 2010-06, Vol.32 (2), p.117-125

2010

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Erratum: Consortium biology in immunology: the perspective from the Immunological Genome Project

Nature reviews. Immunology, 2014-08, Vol.14 (8), p.578-578

2014

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Novel Potent Selective Orally Active S1P5 Receptor Antagonists

Isolation of Microglia and Analysis of Protein Expression by Flow Cytometry: Avoiding the Pitfall of Microglia Background Autofluorescence

Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations

RNA-Seq and CyTOF immuno-profiling of regenerating lacrimal glands identifies a novel subset of cells expressing muscle-related proteins

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis

Association between T follicular helper cells and T peripheral helper cells with B-cell biomarkers and disease activity in primary Sjögren syndrome

Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3

Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation

Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors

Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model

Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis

Corrigendum to “Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors” [Bioorg. Med. Chem. Lett. 60 (2022) 128549]

Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells

Identification of Novel CD4+ T Cell Subsets in the Target Tissue of Sjögren's Syndrome and Their Differential Regulation by the Lymphotoxin/LIGHT Signaling Axis

Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis

Osteopontin associates with brain T RM -cell transcriptome and compartmentalization in donors with and without multiple sclerosis

Multiplicity and plasticity of natural killer cell signaling pathways

The proline-rich sequence of CD3 controls T cell antigen receptor expression on and signaling potency in preselection CD4 + CD8 + thymocytes

LAT signaling pathology: an “autoimmune” condition without T cell self-reactivity

Consortium biology in immunology: the perspective from the Immunological Genome Project

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes

Erratum: Consortium biology in immunology: the perspective from the Immunological Genome Project

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