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Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Molecular cell, 2017-04, Vol.66 (1), p.154-162.e10

2017

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Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

Nature communications, 2018-12, Vol.9 (1), p.5138-13, Article 5138

2018

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miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease

Cell death & disease, 2019-08, Vol.10 (8), p.589-15, Article 589

2019

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Huang-Lian-Jie-Du decoction alleviates depressive-like behaviors in dextran sulfate sodium-induced colitis mice via Trem2/Dap12 pathway

Journal of ethnopharmacology, 2023-10, Vol.315, p.116658-116658, Article 116658

2023

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Urantide alleviates atherosclerosis-related liver and kidney injury via the Wnt/β-catenin signaling pathway in ApoE(−/−) mice

Herz, 2024-08, Vol.49 (4), p.282-295

2024

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Huang Lian Jie Du decoction attenuated colitis via suppressing the macrophage Csf1r/Src pathway and modulating gut microbiota

Frontiers in immunology, 2024-09, Vol.15, p.1375781

2024

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G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-α and IL-1β in mouse model of Parkinson's disease

International journal of neuroscience, 2023-03, Vol.133 (3), p.278-289

2023

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An Innovative Aggregation-Induced Emission-Based NIR Fluorescent Probe for Visualizing Carboxylesterases in Living Cells, Zebrafish, and Tumor-Bearing Mice

Molecules (Basel, Switzerland), 2024-08, Vol.29 (15), p.3660

2024

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Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents

European journal of medicinal chemistry, 2016-03, Vol.111, p.126-137

2016

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The polysaccharide isolated from Pleurotus nebrodensis (PN-S) shows immune-stimulating activity in RAW264.7 macrophages

Chinese journal of natural medicines, 2015-05, Vol.13 (5), p.355-360

2015

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Activation of RAS/ERK alone is insufficient to inhibit RXRα function and deplete retinoic acid in hepatocytes

Biochemical and biophysical research communications, 2014-09, Vol.452 (3), p.801-807

2014

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Programmed vaccination may increase the prevalence of asthma and allergic diseases

American journal of rhinology & allergy, 2016-07, Vol.30 (4), p.113-e117

2016

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Cellular adjustment of gastric cancer for hepatic metastasis in successive orthotopic implantation model

Cancer biology & therapy, 2006-10, Vol.5 (10), p.1313-1319

2006

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Application of mesenchymal stem cells as a vehicle to deliver replication-competent adenovirus for treating malignant glioma

Ai zheng, 2012-05, Vol.31 (5), p.233-240

2012

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Experimental study of protective effect of pueraria compound on the cerebral ischemic injury

Zhongguo zhongyao zazhi, 2005-04, Vol.30 (7), p.548

2005

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Genetic analysis of liver metastatic cell lines with different metastatic potential

Asian Pacific journal of cancer prevention : APJCP, 2011, Vol.12 (12), p.3257

2011

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Stimulation of endothelial non-neuronal muscarinic receptor attenuates the progression of atherosclerosis via inhibiting endothelial cells activation

Zhongguo ying yong sheng li xue za zhi, 2014-11, Vol.30 (6), p.549

2014

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Different Strategies for Preparation of Non-tagged rV270 Protein and Its Efficacy against Yersinia Pestis Challenge

Biomedical and environmental sciences, 2010-10, Vol.23 (5), p.333-340

2010

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Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes

Nature communications, 2019-06, Vol.10 (1), p.2702-14, Article 2702

2019

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Extraction of a Novel Cold-Water-Soluble Polysaccharide from Astragalus membranaceus and Its Antitumor and Immunological Activities

Molecules (Basel, Switzerland), 2017-12, Vol.23 (1), p.62

2017

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ROS/TXNIP pathway contributes to thrombin induced NLRP3 inflammasome activation and cell apoptosis in microglia

Biochemical and biophysical research communications, 2017-04, Vol.485 (2), p.499-505

2017

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Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs

Cellular physiology and biochemistry, 2015-11, Vol.37 (5), p.1693-1711

2015

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Caveolin-1 in the anterior cingulate cortex modulates chronic neuropathic pain via regulation of NMDA receptor 2B subunit

The Journal of neuroscience, 2015-01, Vol.35 (1), p.36-52

2015

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Synthesis, biological evaluation and molecular modeling of dihydro-pyrazolyl-thiazolinone derivatives as potential COX-2 inhibitors

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (22), p.6648-6654

2012

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Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease

Huang-Lian-Jie-Du decoction alleviates depressive-like behaviors in dextran sulfate sodium-induced colitis mice via Trem2/Dap12 pathway

Urantide alleviates atherosclerosis-related liver and kidney injury via the Wnt/β-catenin signaling pathway in ApoE(−/−) mice

Huang Lian Jie Du decoction attenuated colitis via suppressing the macrophage Csf1r/Src pathway and modulating gut microbiota

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)

G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-α and IL-1β in mouse model of Parkinson's disease

An Innovative Aggregation-Induced Emission-Based NIR Fluorescent Probe for Visualizing Carboxylesterases in Living Cells, Zebrafish, and Tumor-Bearing Mice

Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents

The polysaccharide isolated from Pleurotus nebrodensis (PN-S) shows immune-stimulating activity in RAW264.7 macrophages

Activation of RAS/ERK alone is insufficient to inhibit RXRα function and deplete retinoic acid in hepatocytes

Programmed vaccination may increase the prevalence of asthma and allergic diseases

Cellular adjustment of gastric cancer for hepatic metastasis in successive orthotopic implantation model

Application of mesenchymal stem cells as a vehicle to deliver replication-competent adenovirus for treating malignant glioma

Experimental study of protective effect of pueraria compound on the cerebral ischemic injury

Genetic analysis of liver metastatic cell lines with different metastatic potential

Stimulation of endothelial non-neuronal muscarinic receptor attenuates the progression of atherosclerosis via inhibiting endothelial cells activation

Different Strategies for Preparation of Non-tagged rV270 Protein and Its Efficacy against Yersinia Pestis Challenge

Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes

Extraction of a Novel Cold-Water-Soluble Polysaccharide from Astragalus membranaceus and Its Antitumor and Immunological Activities

ROS/TXNIP pathway contributes to thrombin induced NLRP3 inflammasome activation and cell apoptosis in microglia

Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs

Caveolin-1 in the anterior cingulate cortex modulates chronic neuropathic pain via regulation of NMDA receptor 2B subunit

Synthesis, biological evaluation and molecular modeling of dihydro-pyrazolyl-thiazolinone derivatives as potential COX-2 inhibitors

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