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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2651-2662

2014

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IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

Trends in endocrinology and metabolism, 2009-05, Vol.20 (4), p.153-162

2009

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MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.410-425

2014

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The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

American journal of physiology: endocrinology and metabolism, 2016-01, Vol.310 (1), p.E24-E31

2016

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IGF-I and IGF-II effects on local IGF system and signaling pathways in gilthead sea bream ( Sparus aurata ) cultured myocytes

General and comparative endocrinology, 2016-06, Vol.232, p.7-16

2016

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Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

The Journal of neuroscience, 2015-08, Vol.35 (33), p.11500-11513

2015

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Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation

General and comparative endocrinology, 2010-07, Vol.167 (3), p.344-351

2010

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109542-109542, Article 109542

2021

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Mapping the growth hormone–Stat5b–IGF-I transcriptional circuit

Trends in endocrinology and metabolism, 2012-04, Vol.23 (4), p.186-193

Rotwein, Peter

2012

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IGF binding proteins in cancer: mechanistic and clinical insights

Nature reviews. Cancer, 2014-05, Vol.14 (5), p.329-341

Baxter, Robert C

2014

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Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Drug testing and analysis, 2021-07, Vol.13 (7), p.1256-1269

2021

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Cellular and molecular life sciences : CMLS, 2016-01, Vol.73 (2), p.271-290

2016

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Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2017-01, Vol.55 (2), p.849-864

2017

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The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

Atherosclerosis, 2012-01, Vol.220 (1), p.102-109

2012

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High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

Clinical cancer research, 2011-04, Vol.17 (8), p.2314-2327

2011

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-12, Vol.34 (12), p.612-619

2009

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Endothelial cells and the IGF system

Journal of molecular endocrinology, 2015-02, Vol.54 (1), p.R1-R13

Bach, Leon A

2015

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Effects of GH/IGF axis on bone and cartilage

Molecular and cellular endocrinology, 2021-01, Vol.519, p.111052-111052, Article 111052

2021

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Effects of fasting on IGF-I, IGF-II, and IGF-binding protein mRNA concentrations in channel catfish ( Ictalurus punctatus)

Domestic animal endocrinology, 2009-08, Vol.37 (2), p.74-83

2009

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Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

Molecular and Cellular Biology, 2012-10, Vol.32 (20), p.4116-4130

2012

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Environmental estrogens inhibit insulin-like growth factor (IGF) receptor mRNA expression, IGF binding, and IGF signaling ex vivo in rainbow trout (Oncorhynchus mykiss)

General and comparative endocrinology, 2023-01, Vol.330, p.114125-114125, Article 114125

2023

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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

IGF-I and IGF-II effects on local IGF system and signaling pathways in gilthead sea bream ( Sparus aurata ) cultured myocytes

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation

Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Mapping the growth hormone–Stat5b–IGF-I transcriptional circuit

IGF binding proteins in cancer: mechanistic and clinical insights

Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

Therapeutic Targeting of the IGF Axis

Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Endothelial cells and the IGF system

Effects of GH/IGF axis on bone and cartilage

Effects of fasting on IGF-I, IGF-II, and IGF-binding protein mRNA concentrations in channel catfish ( Ictalurus punctatus)

Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

Environmental estrogens inhibit insulin-like growth factor (IGF) receptor mRNA expression, IGF binding, and IGF signaling ex vivo in rainbow trout (Oncorhynchus mykiss)

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