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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

American journal of physiology. Heart and circulatory physiology, 2013-08, Vol.305 (4), p.H459-H476

2013

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Molecular cell, 2019-02, Vol.73 (4), p.775-787.e10

2019

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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

International journal of molecular sciences, 2016-11, Vol.17 (12), p.1973

2016

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Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Human pathology, 2016-03, Vol.49, p.27-32

2016

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Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167157-167157, Article 167157

2024

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A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167131-167131, Article 167131

2024

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Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Expert opinion on drug metabolism & toxicology, 2014-08, Vol.10 (8), p.1061-1067

2014

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Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4710

2024

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Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

Aging (Albany, NY.), 2024-04, Vol.16 (8), p.7141

2024

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Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Medicinal research reviews, 2015-05, Vol.35 (3), p.520-553

2015

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Brain aging, Alzheimer's disease, and mitochondria

Biochimica et biophysica acta, 2011-12, Vol.1812 (12), p.1630-1639

Swerdlow, Russell H.

2011

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Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

Journal of cellular physiology, 2021-11, Vol.236 (11), p.7612-7624

2021

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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Signal transduction and targeted therapy, 2024-05, Vol.9 (1), p.133-17, Article 133

2024

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A neuroglobin-based high-affinity ligand trap reverses carbon monoxide–induced mitochondrial poisoning

The Journal of biological chemistry, 2020-05, Vol.295 (19), p.6357-6371

2020

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Complex I Is the Major Site of Mitochondrial Superoxide Production by Paraquat

The Journal of biological chemistry, 2008-01, Vol.283 (4), p.1786-1798

2008

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CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Acta neuropathologica communications, 2020-03, Vol.8 (1), p.32-32, Article 32

2020

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Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Biochimica et biophysica acta. Molecular basis of disease, 2020-07, Vol.1866 (7), p.165768-165768, Article 165768

2020

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Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Genes & development, 2020-03, Vol.34 (5-6), p.428-445

2020

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Insulin resistance: Review of the underlying molecular mechanisms

Journal of cellular physiology, 2019-06, Vol.234 (6), p.8152-8161

2019

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Role of Mitochondria in Ferroptosis

Molecular cell, 2019-01, Vol.73 (2), p.354-363.e3

2019

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Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

Nature neuroscience, 2019-10, Vol.22 (10), p.1635

2019

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The hallmarks of mitochondrial dysfunction in chronic kidney disease

Kidney international, 2017-11, Vol.92 (5), p.1051-1057

2017

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Toxicity of Familial ALS-Linked SOD1 Mutants from Selective Recruitment to Spinal Mitochondria

Neuron (Cambridge, Mass.), 2004-07, Vol.43 (1), p.5-17

2004

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Mitochondria: In Sickness and in Health

Cell, 2012-03, Vol.148 (6), p.1145-1159

2012

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The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease

Cell reports (Cambridge), 2018-06, Vol.23 (10), p.2976-2988

2018

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Brain aging, Alzheimer's disease, and mitochondria

Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

A neuroglobin-based high-affinity ligand trap reverses carbon monoxide–induced mitochondrial poisoning

Complex I Is the Major Site of Mitochondrial Superoxide Production by Paraquat

CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Insulin resistance: Review of the underlying molecular mechanisms

Role of Mitochondria in Ferroptosis

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

The hallmarks of mitochondrial dysfunction in chronic kidney disease

Toxicity of Familial ALS-Linked SOD1 Mutants from Selective Recruitment to Spinal Mitochondria

Mitochondria: In Sickness and in Health

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease

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