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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Antimicrobial agents and chemotherapy, 2020-06, Vol.64 (7)

2020

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Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery

Critical reviews in microbiology, 2017-11, Vol.43 (6), p.753-778

2017

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Uracil within DNA: an actor of antiviral immunity

Retrovirology, 2008-06, Vol.5 (1), p.45-45, Article 45

2008

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Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

European journal of medicinal chemistry, 2019-01, Vol.161 (4), p.323-333

2019

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Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons

Journal of general virology, 2014-11, Vol.95 (Pt 11), p.2462-2467

2014

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Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling

Virology (New York, N.Y.), 2010-09, Vol.404 (2), p.319-330

2010

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Functional Role of HIV-1 Virion-associated Uracil DNA Glycosylase 2 in the Correction of G:U Mispairs to G:C Pairs

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.4566-4571

2003

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Visna Virus dUTPase Is Dispensable for Neuropathogenicity

Journal of Virology, 1998-02, Vol.72 (2), p.1657-1661

1998

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Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

European journal of medicinal chemistry, 2017-01, Vol.125, p.865-880

2017

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A novel class of small molecule inhibitors targeting the chikungunya virus capping machinery with a high barrier to resistance

Access microbiology, 2019-12, Vol.1 (10)

2019

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HIV-1-Associated Uracil DNA Glycosylase Activity Controls dUTP Misincorporation in Viral DNA and Is Essential to the HIV-1 Life Cycle

Molecular cell, 2005-02, Vol.17 (4), p.479-490

2005

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Toscana virus cap-snatching and initiation of transcription

Journal of general virology, 2017-11, Vol.98 (11), p.2676-2688

2017

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Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

European journal of medicinal chemistry, 2016-02, Vol.109, p.146-156

2016

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Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

European journal of medicinal chemistry, 2018-01, Vol.143, p.1667-1676

2018

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Identification of [1,2,3]Triazolo[4,5‑d]pyrimidin-7(6H)‑ones as Novel Inhibitors of Chikungunya Virus Replication

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.4000-4008

2014

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Japanese encephalitis in a French traveler to Nepal

Journal of neurovirology, 2014-02, Vol.20 (1), p.99-102

2014

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Lack of Functional Receptors Is the Only Barrier That Prevents Caprine Arthritis-Encephalitis Virus from Infecting Human Cells

Journal of Virology, 2000-09, Vol.74 (18), p.8343-8348

2000

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dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions

Journal of Virology, 1997-06, Vol.71 (6), p.4522-4530

1997

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Reversion of the Lethal Phenotype of an HIV-1 Integrase Mutant Virus by Overexpression of the Same Integrase Mutant Protein

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.20724-20730

2003

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Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIVMAC viral particles

Virology (New York, N.Y.), 2003-03, Vol.307 (2), p.283-289

2003

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Replication properties of dUTPase-deficient mutants of caprine and ovine lentiviruses

Journal of Virology, 1996-02, Vol.70 (2), p.1213-1217

1996

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Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV(MAC) viral particles

Virology (New York, N.Y.), 2003-03, Vol.307 (2), p.283-289

2003

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Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV MAC viral particles

Virology (New York, N.Y.), 2003, Vol.307 (2), p.283-289

2003

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Inhibition of the Replication of Different Strains of Chikungunya Virus by 3‑Aryl-[1,2,3]triazolo[4,5‑d]pyrimidin-7(6H)‑ones

ACS infectious diseases, 2018-04, Vol.4 (4), p.605-619

2018

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Glutamic Residue 438 within the Protease-Sensitive Subdomain of HIV-1 Reverse Transcriptase Is Critical for Heterodimer Processing in Viral Particles

Virology (New York, N.Y.), 2001-11, Vol.290 (2), p.300-308

2001

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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery

Uracil within DNA: an actor of antiviral immunity

Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons

Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling

Functional Role of HIV-1 Virion-associated Uracil DNA Glycosylase 2 in the Correction of G:U Mispairs to G:C Pairs

Visna Virus dUTPase Is Dispensable for Neuropathogenicity

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

A novel class of small molecule inhibitors targeting the chikungunya virus capping machinery with a high barrier to resistance

HIV-1-Associated Uracil DNA Glycosylase Activity Controls dUTP Misincorporation in Viral DNA and Is Essential to the HIV-1 Life Cycle

Toscana virus cap-snatching and initiation of transcription

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

Identification of [1,2,3]Triazolo[4,5‑d]pyrimidin-7(6H)‑ones as Novel Inhibitors of Chikungunya Virus Replication

Japanese encephalitis in a French traveler to Nepal

Lack of Functional Receptors Is the Only Barrier That Prevents Caprine Arthritis-Encephalitis Virus from Infecting Human Cells

dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions

Reversion of the Lethal Phenotype of an HIV-1 Integrase Mutant Virus by Overexpression of the Same Integrase Mutant Protein

Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIVMAC viral particles

Replication properties of dUTPase-deficient mutants of caprine and ovine lentiviruses

Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV(MAC) viral particles

Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV MAC viral particles

Inhibition of the Replication of Different Strains of Chikungunya Virus by 3‑Aryl-[1,2,3]triazolo[4,5‑d]pyrimidin-7(6H)‑ones

Glutamic Residue 438 within the Protease-Sensitive Subdomain of HIV-1 Reverse Transcriptase Is Critical for Heterodimer Processing in Viral Particles

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