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Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

Frontiers in genetics, 2013, Vol.4, p.24

2013

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Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem

Frontiers in genetics, 2013, Vol.4, p.12

2013

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Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Analytical and bioanalytical chemistry, 2008-11, Vol.392 (6), p.1093-1108

2008

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Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8768

2024

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Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD

International journal of molecular sciences, 2023-08, Vol.24 (17), p.13222

2023

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Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Scientific reports, 2021-01, Vol.11 (1), p.1000-1000, Article 1000

2021

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Antwort

Deutsche medizinische Wochenschrift, 2019-02, Vol.144 (4), p.289-289

Klein, Kathrin

2019

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Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease

PloS one, 2011-08, Vol.6 (8), p.e23506-e23506

2011

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Sustainable implementation of antibiotic stewardship on a surgical intensive care unit evaluated over a 10-year period

Infection, 2020-02, Vol.48 (1), p.117-124

2020

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Aortic valve calcification is subject to aortic stenosis severity and the underlying flow pattern

Heart and vessels, 2021-02, Vol.36 (2), p.242-251

2021

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Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B66, is responsible for decreased expression and activity of CYP2B6 in liver

The Journal of pharmacology and experimental therapeutics, 2008-04, Vol.325 (1), p.284-292

2008

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Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα)

Molecular pharmacology, 2013-03, Vol.83 (3), p.709-718

2013

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Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Frontiers in pharmacology, 2021-11, Vol.12, p.769703-769703

2021

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Function and Localization Dynamics of Bifunctional Penicillin-Binding Proteins in Caulobacter crescentus

Journal of bacteriology, 2014-04, Vol.196 (8), p.1627-1639

2014

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A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Frontiers in genetics, 2019, Vol.10, p.7

2019

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Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7468

2022

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Feasibility, Accuracy, and Reproducibility of Aortic Valve Sizing for Transcatheter Aortic Valve Implantation Using Virtual Reality

Journal of the American Heart Association, 2024-08, Vol.13 (15), p.e034086

2024

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Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver

Drug metabolism and disposition, 2008-10, Vol.36 (10), p.2113-2120

2008

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Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes

Drug metabolism and disposition, 2010-09, Vol.38 (9), p.1589-1597

2010

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Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia

Advanced science, 2022-12, Vol.9 (34), p.e2203368-n/a

2022

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Nanofluidic Immobilization and Growth Detection of Escherichia coli in a Chip for Antibiotic Susceptibility Testing

Biosensors (Basel), 2020-09, Vol.10 (10), p.135

2020

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Real-world experience with the cusp-overlap deployment technique in transcatheter aortic valve replacement: A propensity-matched analysis

Frontiers in cardiovascular medicine, 2022-08, Vol.9, p.847568-847568

2022

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The effect of genetic variants in the transcription factor TSPYL family on the CYP3A4 mediated cyclosporine metabolism in kidney transplant patients

Clinical and translational science, 2024-02, Vol.17 (2), p.e13729-n/a

2024

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Rapid CYP450 quantification by immunoaffinity-mass spectrometry

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S27-S27

2019

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Echocardiographic-Fluoroscopic Fusion Imaging Improves Interventionalists' Learning Curve for Percutaneous Left Atrial Appendage Closure-Initial, Single-Center, Retrospective Observations

Journal of cardiovascular development and disease, 2024-02, Vol.11 (3), p.82

2024

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Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis

Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD

Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Antwort

Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease

Sustainable implementation of antibiotic stewardship on a surgical intensive care unit evaluated over a 10-year period

Aortic valve calcification is subject to aortic stenosis severity and the underlying flow pattern

Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B66, is responsible for decreased expression and activity of CYP2B6 in liver

Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα)

Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Function and Localization Dynamics of Bifunctional Penicillin-Binding Proteins in Caulobacter crescentus

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

Feasibility, Accuracy, and Reproducibility of Aortic Valve Sizing for Transcatheter Aortic Valve Implantation Using Virtual Reality

Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver

Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes

Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia

Nanofluidic Immobilization and Growth Detection of Escherichia coli in a Chip for Antibiotic Susceptibility Testing

Real-world experience with the cusp-overlap deployment technique in transcatheter aortic valve replacement: A propensity-matched analysis

The effect of genetic variants in the transcription factor TSPYL family on the CYP3A4 mediated cyclosporine metabolism in kidney transplant patients

Rapid CYP450 quantification by immunoaffinity-mass spectrometry

Echocardiographic-Fluoroscopic Fusion Imaging Improves Interventionalists' Learning Curve for Percutaneous Left Atrial Appendage Closure-Initial, Single-Center, Retrospective Observations

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