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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Annual review of nutrition, 2016-07, Vol.36 (1), p.275-299

2016

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Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Journal of lipid research, 2018-09, Vol.59 (9), p.1714-1728

2018

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Antiatherogenic properties of flavonoids: Implications for cardiovascular health

Canadian journal of cardiology, 2010-03, Vol.26, p.17A-21A

2010

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The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Journal of lipid research, 2020-03, Vol.61 (3), p.387-402

2020

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Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Journal of lipid research, 2013-03, Vol.54 (3), p.711-724

2013

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Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

Gastroenterology (New York, N.Y. 1943), 2009-11, Vol.137 (5), p.1795-1804

2009

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PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

Journal of lipid research, 2014-07, Vol.55 (7), p.1254-1266

2014

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molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

Journal of lipid research, 2007-03, Vol.48 (3), p.699-708

2007

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Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

The Journal of biological chemistry, 2007-02, Vol.282 (8), p.5207-5216

2007

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Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

PPAR Research, 2012-01, Vol.2012, p.857142-9

2012

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Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Journal of lipid research, 2001-05, Vol.42 (5), p.725-734

2001

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PCSK9: Regulation and Target for Drug Development for Dyslipidemia

Annual review of pharmacology and toxicology, 2017-01, Vol.57, p.223

2017

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Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Journal of lipid research, 2008-10, Vol.49 (10), p.2218-2229

2008

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Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

Cardiovascular diabetology, 2008-03, Vol.7 (1), p.5-5, Article 5

2008

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Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

Nature genetics, 2010-08, Vol.42 (8), p.684-687

2010

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Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

Biochemical journal, 2002-09, Vol.366 (Pt 2), p.531-539

2002

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Naringenin enhances the regression of atherosclerosis induced by a chow diet in Ldlr−/− mice

Atherosclerosis, 2019-07, Vol.286, p.60-70

2019

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APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

Journal of lipid research, 2010-04, Vol.51 (4), p.843-848

2010

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Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample

BMC medical genetics, 2007-12, Vol.8 (1), p.80-80

2007

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Canadian global village reality Anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent

Canadian family physician, 2010-05, Vol.56 (5), p.e174-e182

2010

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Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

Trends in pharmacological sciences (Regular ed.), 2005-07, Vol.26 (7), p.335-340

2005

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Regulation of Macrophage Cholesterol Efflux through Hydroxymethylglutaryl-CoA Reductase Inhibition

The Journal of biological chemistry, 2005-06, Vol.280 (23), p.22212-22221

2005

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Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs

Journal of lipid research, 1999-07, Vol.40 (7), p.1317-1327

1999

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Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux

The Journal of biological chemistry, 2005-06, Vol.280 (23), p.22212-22221

2005

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Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin

Journal of lipid research, 1999-06, Vol.40 (6), p.1078-1089

1999

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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Antiatherogenic properties of flavonoids: Implications for cardiovascular health

The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

PCSK9: Regulation and Target for Drug Development for Dyslipidemia

Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

Naringenin enhances the regression of atherosclerosis induced by a chow diet in Ldlr−/− mice

APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample

Canadian global village reality Anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent

Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

Regulation of Macrophage Cholesterol Efflux through Hydroxymethylglutaryl-CoA Reductase Inhibition

Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux

Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin

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