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An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.624

2021

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Thiazoles and Thiazolidinones as COX/LOX Inhibitors

Molecules (Basel, Switzerland), 2018-03, Vol.23 (3), p.685

2018

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Thiazole Ring-A Biologically Active Scaffold

Molecules (Basel, Switzerland), 2021-05, Vol.26 (11), p.3166

2021

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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Bioorganic & medicinal chemistry, 2020-04, Vol.28 (7), p.115403-115403, Article 115403

2020

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Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

International journal of biological macromolecules, 2020-11, Vol.163, p.1970-1988

2020

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Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

Bioorganic chemistry, 2020-05, Vol.98, p.103761, Article 103761

2020

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Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer's Inhibitors

Molecules (Basel, Switzerland), 2023-01, Vol.28 (2), p.559

2023

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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

Nature chemical biology, 2018-02, Vol.14 (2), p.163-170

2018

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Recent developments and biological activities of thiazolidinone derivatives: A review

Bioorganic & medicinal chemistry, 2012-06, Vol.20 (11), p.3378-3395

2012

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Antioxidant activity of novel imidazo[2,1-b]thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

Bioorganic chemistry, 2020-10, Vol.103, p.104220, Article 104220

2020

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Thiazole-Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Molecules (Basel, Switzerland), 2021-05, Vol.26 (10), p.2847

2021

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Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds

Bioorganic chemistry, 2020-09, Vol.102, p.104110, Article 104110

2020

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Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole scaffold

Bioorganic & medicinal chemistry, 2019-05, Vol.27 (10), p.2041-2051

2019

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The Arabidopsis Pleiotropic Drug Resistance Transporters PEN3 and PDR12 Mediate Camalexin Secretion for Resistance to Botrytis cinerea

The Plant cell, 2019-09, Vol.31 (9), p.2206-2222

2019

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Self-renewal as a therapeutic target in human colorectal cancer

Nature medicine, 2014-01, Vol.20 (1), p.29-36

2014

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Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors

Bioorganic & medicinal chemistry, 2016-03, Vol.24 (6), p.1298-1307

2016

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Muscarine, imidazole, oxazole, and thiazole alkaloids

Natural product reports, 2011-01, Vol.28 (6), p.1143-1191

Jin, Zhong

2011

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Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2011-05, Vol.19 (10), p.3135-3140

2011

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Synthesis, Molecular Docking Studies and In Silico ADMET Screening of New Heterocycles Linked Thiazole Conjugates as Potent Anti-Hepatic Cancer Agents

Molecules (Basel, Switzerland), 2021-03, Vol.26 (6), p.1705

2021

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Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase

Bioorganic chemistry, 2015-10, Vol.62, p.15-21

2015

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Design, synthesis and molecular docking of novel D-ring substituted steroidal 4,5-dihydropyrazole thiazole derivatives that act as iNOS/COX-2 inhibitors with potent anti-inflammatory activity against LPS-induced RAW264.7 macrophage cells

The Journal of steroid biochemistry and molecular biology, 2024-06, Vol.240, p.106478, Article 106478

2024

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Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors

Bioorganic & medicinal chemistry, 2021-09, Vol.46, p.116367-116367, Article 116367

2021

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Identification and development of thiazole leads as COX-2/5-LOX inhibitors through in-vitro and in-vivo biological evaluation for anti-inflammatory activity

Bioorganic chemistry, 2020-07, Vol.100, p.103882-103882, Article 103882

2020

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Derivatives of pyridine and thiazole hybrid: Synthesis, DFT, biological evaluation via antimicrobial and DNA cleavage activity

Bioorganic chemistry, 2020-01, Vol.95, p.103476, Article 103476

2020

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IAP antagonists induce anti-tumor immunity in multiple myeloma

Nature medicine, 2016-12, Vol.22 (12), p.1411-1420

2016

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An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives

Thiazoles and Thiazolidinones as COX/LOX Inhibitors

Thiazole Ring-A Biologically Active Scaffold

Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer's Inhibitors

Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

Recent developments and biological activities of thiazolidinone derivatives: A review

Antioxidant activity of novel imidazo[2,1-b]thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

Thiazole-Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds

Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole scaffold

The Arabidopsis Pleiotropic Drug Resistance Transporters PEN3 and PDR12 Mediate Camalexin Secretion for Resistance to Botrytis cinerea

Self-renewal as a therapeutic target in human colorectal cancer

Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors

Muscarine, imidazole, oxazole, and thiazole alkaloids

Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

Synthesis, Molecular Docking Studies and In Silico ADMET Screening of New Heterocycles Linked Thiazole Conjugates as Potent Anti-Hepatic Cancer Agents

Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase

Design, synthesis and molecular docking of novel D-ring substituted steroidal 4,5-dihydropyrazole thiazole derivatives that act as iNOS/COX-2 inhibitors with potent anti-inflammatory activity against LPS-induced RAW264.7 macrophage cells

Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors

Identification and development of thiazole leads as COX-2/5-LOX inhibitors through in-vitro and in-vivo biological evaluation for anti-inflammatory activity

Derivatives of pyridine and thiazole hybrid: Synthesis, DFT, biological evaluation via antimicrobial and DNA cleavage activity

IAP antagonists induce anti-tumor immunity in multiple myeloma

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