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The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4507

2020

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Mechanisms of ATM Activation

Annual review of biochemistry, 2015-06, Vol.84 (1), p.711-738

Paull, Tanya T

2015

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Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Journal of cellular physiology, 2018-06, Vol.233 (6), p.4634-4642

2018

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Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1353

2022

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The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

PLoS biology, 2019-10, Vol.17 (10), p.e3000509-e3000509

2019

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Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes

Breast cancer research : BCR, 2019-08, Vol.21 (1), p.90-90, Article 90

2019

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PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (39), p.24427-24433

2020

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Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis

PloS one, 2012-09, Vol.7 (9), p.e45427-e45427

2012

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Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

eLife, 2014-11, Vol.3, p.e04135-e04135

2014

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Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

Lipids in health and disease, 2017-04, Vol.16 (1), p.77-77, Article 77

2017

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The PI3K/Akt Pathway in Meta-Inflammation

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15330

2022

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Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Nature communications, 2018-07, Vol.9 (1), p.2639-13, Article 2639

2018

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Dahuang Zhechong pill attenuates CCl4‐induced rat liver fibrosis via the PI3K‐Akt signaling pathway

Journal of cellular biochemistry, 2020-02, Vol.121 (2), p.1431-1440

2020

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Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cells

PloS one, 2014-04, Vol.9 (4), p.e94496-e94496

2014

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Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

Journal of cellular physiology, 2017-12, Vol.232 (12), p.3786-3797

2017

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mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5841

2019

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TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling

Cancer letters, 2019-06, Vol.452, p.1-13

2019

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Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

PloS one, 2014-04, Vol.9 (4), p.e95219-e95219

2014

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A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

Science signaling, 2022-07, Vol.15 (743), p.eabl9169

2022

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Combining NanoKnife with M1 oncolytic virus enhances anticancer activity in pancreatic cancer

Cancer letters, 2021-04, Vol.502, p.9-24

2021

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A class of highly selective inhibitors bind to an active state of PI3Kγ

Nature chemical biology, 2019-04, Vol.15 (4), p.348

2019

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Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium

eLife, 2015-07, Vol.4, p.e06866-e06866

2015

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ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (20), p.E3964-E3973

2017

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Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

PloS one, 2011-05, Vol.6 (5), p.e20164

2011

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Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Journal of neuroinflammation, 2021-11, Vol.18 (1), p.276-276, Article 276

2021

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The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

Mechanisms of ATM Activation

Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma

The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes

PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition

Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

The PI3K/Akt Pathway in Meta-Inflammation

Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Dahuang Zhechong pill attenuates CCl4‐induced rat liver fibrosis via the PI3K‐Akt signaling pathway

Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cells

Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

Combining NanoKnife with M1 oncolytic virus enhances anticancer activity in pancreatic cancer

A class of highly selective inhibitors bind to an active state of PI3Kγ

Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium

ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

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