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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (48), p.12176-12181

2018

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Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6829-6834

2013

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Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

PloS one, 2014-04, Vol.9 (4), p.e95219-e95219

2014

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Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

PloS one, 2011-05, Vol.6 (5), p.e20164

2011

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Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells

PloS one, 2012-08, Vol.7 (8), p.e44107

2012

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Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Journal of medicinal chemistry, 2022-05, Vol.65 (10), p.7399-7413

2022

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Klotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury

Scientific reports, 2023-11, Vol.13 (1), p.20312-20312, Article 20312

2023

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p85β regulates autophagic degradation of AXL to activate oncogenic signaling

Nature communications, 2020-05, Vol.11 (1), p.2291-15, Article 2291

2020

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PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis

PloS one, 2011-01, Vol.6 (1), p.e15909-e15909

2011

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PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

PloS one, 2016-08, Vol.11 (8), p.e0160686-e0160686

2016

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PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration

Scientific reports, 2017-02, Vol.7 (1), p.42575-42575, Article 42575

2017

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Anti-fibrotic actions of interleukin-10 against hypertrophic scarring by activation of PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts

PloS one, 2014-05, Vol.9 (5), p.e98228-e98228

2014

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Structure of the human ATM kinase and mechanism of Nbs1 binding

eLife, 2022-01, Vol.11

2022

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Sustained GSK3 activity markedly facilitates nerve regeneration

Nature communications, 2014-07, Vol.5 (1), p.4561-4561, Article 4561

2014

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PARP-1–dependent recruitment of cold-inducible RNA-binding protein promotes double-strand break repair and genome stability

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.E1759-E1768

2018

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Cyclocarya paliurus extract activates insulin signaling via Sirtuin1 in C2C12 myotubes and decreases blood glucose level in mice with impaired insulin secretion

PloS one, 2017-08, Vol.12 (8), p.e0183988-e0183988

2017

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TLR3 regulates mycobacterial RNA-induced IL-10 production through the PI3K/AKT signaling pathway

Cellular signalling, 2014-05, Vol.26 (5), p.942-950

2014

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EGF-Induced VEGF Exerts a PI3K-Dependent Positive Feedback on ERK and AKT through VEGFR2 in Hematological In Vitro Models

PloS one, 2016-11, Vol.11 (11), p.e0165876-e0165876

2016

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Cyclic Compressive Stress Regulates Apoptosis in Rat Osteoblasts: Involvement of PI3K/Akt and JNK MAPK Signaling Pathways

PloS one, 2016-11, Vol.11 (11), p.e0165845-e0165845

2016

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Suppression of Virulent Porcine Epidemic Diarrhea Virus Proliferation by the PI3K/Akt/GSK-3α/β Pathway

PloS one, 2016-08, Vol.11 (8), p.e0161508-e0161508

2016

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Essential role of Stat3 in PI3K-induced oncogenic transformation

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13247-13252

2011

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Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

Nutrients, 2018-09, Vol.10 (9), p.1328

2018

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Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function

Scientific reports, 2019-02, Vol.9 (1), p.1468-1468, Article 1468

2019

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mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility

PloS one, 2014-10, Vol.9 (10), p.e110491-e110491

2014

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A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing

PloS one, 2019-10, Vol.14 (10), p.e0223846-e0223846

2019

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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors

Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Klotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury

p85β regulates autophagic degradation of AXL to activate oncogenic signaling

PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis

PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration

Anti-fibrotic actions of interleukin-10 against hypertrophic scarring by activation of PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts

Structure of the human ATM kinase and mechanism of Nbs1 binding

Sustained GSK3 activity markedly facilitates nerve regeneration

PARP-1–dependent recruitment of cold-inducible RNA-binding protein promotes double-strand break repair and genome stability

Cyclocarya paliurus extract activates insulin signaling via Sirtuin1 in C2C12 myotubes and decreases blood glucose level in mice with impaired insulin secretion

TLR3 regulates mycobacterial RNA-induced IL-10 production through the PI3K/AKT signaling pathway

EGF-Induced VEGF Exerts a PI3K-Dependent Positive Feedback on ERK and AKT through VEGFR2 in Hematological In Vitro Models

Cyclic Compressive Stress Regulates Apoptosis in Rat Osteoblasts: Involvement of PI3K/Akt and JNK MAPK Signaling Pathways

Suppression of Virulent Porcine Epidemic Diarrhea Virus Proliferation by the PI3K/Akt/GSK-3α/β Pathway

Essential role of Stat3 in PI3K-induced oncogenic transformation

Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function

mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility

A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing

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