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Seven transmembrane receptors: something old, something new

Acta Physiologica, 2007-05, Vol.190 (1), p.9-19

Lefkowitz, R.J

2007

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Desensitization of G protein-coupled receptors and neuronal functions

Annual review of neuroscience, 2004-01, Vol.27 (1), p.107-144

2004

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The superfamily of heptahelical receptors

Nature cell biology, 2000-07, Vol.2 (7), p.E133-E136

Lefkowitz, Robert J

2000

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Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Current Opinion in Cell Biology, 2001-04, Vol.13 (2), p.139-145

2001

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Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Molecular pharmacology, 2004-07, Vol.66 (1), p.106-112

2004

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Functional consequences of altering myocardial adrenergic receptor signaling

Annual review of physiology, 2000-01, Vol.62 (1), p.237-260

2000

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G protein—coupled receptor kinases

Cell, 1993-08, Vol.74 (3), p.409-412

Lefkowitz, Robert J.

1993

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Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

The Journal of clinical investigation, 2001-04, Vol.107 (8), p.967-974

2001

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Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

Molecular and Cellular Biology, 2000-11, Vol.20 (22), p.8352-8363

2000

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G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.18677-18680

Lefkowitz, R J

1998

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Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

Trends in pharmacological sciences (Regular ed.), 1993-08, Vol.14 (8), p.303-307

1993

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Circulation (New York, N.Y.), 1998-10, Vol.98 (17), p.1783-1789

1998

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Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization

The Journal of biological chemistry, 1993-01, Vol.268 (1), p.337-341

1993

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G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

American journal of physiology. Lung cellular and molecular physiology, 2004-02, Vol.286 (2), p.312-L319

2004

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Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases

The Journal of biological chemistry, 1994-01, Vol.269 (2), p.1125-1130

1994

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Structure and mechanism of the G protein-coupled receptor kinases

The Journal of biological chemistry, 1993-11, Vol.268 (32), p.23735-23738

1993

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Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

The Journal of biological chemistry, 1992-09, Vol.267 (25), p.17882-17890

1992

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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

The Journal of biological chemistry, 1999-05, Vol.274 (20), p.13978-13984

1999

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Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

The Journal of biological chemistry, 1994-03, Vol.269 (9), p.6832-6841

1994

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Binding of G protein beta gamma-subunits to pleckstrin homology domains

The Journal of biological chemistry, 1994-04, Vol.269 (14), p.10217-10220

1994

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Neuron (Cambridge, Mass.), 1999-12, Vol.24 (4), p.1029-1036

1999

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Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

Nature reviews. Neuroscience, 2001-10, Vol.2 (10), p.727-733

2001

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The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

The Journal of biological chemistry, 1993-04, Vol.268 (11), p.8256-8260

1993

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Turning off the signal: desensitization of β‐adrenergic receptor function

The FASEB journal, 1990-08, Vol.4 (11), p.2881-2889

1990

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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Nature (London), 2000-12, Vol.408 (6813), p.720-723

2000

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Seven transmembrane receptors: something old, something new

Desensitization of G protein-coupled receptors and neuronal functions

The superfamily of heptahelical receptors

Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Functional consequences of altering myocardial adrenergic receptor signaling

G protein—coupled receptor kinases

Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization

G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases

Structure and mechanism of the G protein-coupled receptor kinases

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

Binding of G protein beta gamma-subunits to pleckstrin homology domains

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

Turning off the signal: desensitization of β‐adrenergic receptor function

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

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