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Seven transmembrane receptors: something old, something new

Acta Physiologica, 2007-05, Vol.190 (1), p.9-19

Lefkowitz, R.J

2007

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Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

The Journal of clinical investigation, 2001-04, Vol.107 (8), p.967-974

2001

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Circulation (New York, N.Y.), 1998-10, Vol.98 (17), p.1783-1789

1998

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Turning off the signal: desensitization of β‐adrenergic receptor function

The FASEB journal, 1990-08, Vol.4 (11), p.2881-2889

1990

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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Nature (London), 2000-12, Vol.408 (6813), p.720-723

2000

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Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

Progress in neurobiology, 2002-02, Vol.66 (2), p.61-79

2002

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Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

Circulation research, 2002-10, Vol.91 (8), p.672-680

2002

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Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart

Circulation research, 2000-01, Vol.86 (1), p.43-43

2000

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Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

Nature (London), 1992-09, Vol.359 (6391), p.147-150

1992

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In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

Circulation (New York, N.Y.), 1999-08, Vol.100 (6), p.648-653

1999

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Catecholamines, cardiac beta-adrenergic receptors, and heart failure

Circulation (New York, N.Y.), 2000-04, Vol.101 (14), p.1634-1637

2000

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Mitogenic signaling via G protein-coupled receptors

Endocrine reviews, 1996-12, Vol.17 (6), p.698-714

1996

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The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

Nature (London), 1988-09, Vol.335 (6188), p.358-360

1988

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Prospects for cardiovascular research

JAMA : the journal of the American Medical Association, 2001-02, Vol.285 (5), p.581

2001

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Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Nature (London), 1985-09, Vol.317 (6033), p.124-129

1985

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Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

Nature (London), 1987-05, Vol.327 (6117), p.67-70

1987

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In vivo ventricular gene delivery of a β-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

Circulation (New York, N.Y.), 2001-03, Vol.103 (9), p.1311-1316

2001

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Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

Nature (London), 1986-05, Vol.321 (6065), p.75-79

1986

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Adenovirus-mediated gene transfer of the β2-adrenergic receptor to donor hearts enhances cardiac function

Gene therapy, 1999-07, Vol.6 (7), p.1298-1304

1999

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Ex Vivo Adenovirus-Mediated Gene Transfer To The Adult Rat Heart

The Journal of thoracic and cardiovascular surgery, 1998-03, Vol.115 (3), p.623-630

1998

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Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes

The Journal of clinical investigation, 1983-09, Vol.72 (3), p.748-753

1983

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Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice

Circulation (New York, N.Y.), 2001-11, Vol.104 (20), p.2485-2491

2001

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2001: An AAP (Association of American Physicians) odyssey

The Journal of clinical investigation, 2001-10, Vol.108 (7), p.s9-s13

Lefkowitz, R J

2001

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Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors

The New England journal of medicine, 1984-06, Vol.310 (24), p.1570-1579

1984

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Transgenic Manipulation of Myocardial G Protein-Coupled Receptors and Receptor Kinases

Circulation research, 1996-04, Vol.78 (4), p.511-516

1996

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Seven transmembrane receptors: something old, something new

Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Turning off the signal: desensitization of β‐adrenergic receptor function

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

Catecholamines, cardiac beta-adrenergic receptors, and heart failure

Mitogenic signaling via G protein-coupled receptors

The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

Prospects for cardiovascular research

Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

In vivo ventricular gene delivery of a β-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

Adenovirus-mediated gene transfer of the β2-adrenergic receptor to donor hearts enhances cardiac function

Ex Vivo Adenovirus-Mediated Gene Transfer To The Adult Rat Heart

Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes

Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice

2001: An AAP (Association of American Physicians) odyssey

Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors

Transgenic Manipulation of Myocardial G Protein-Coupled Receptors and Receptor Kinases

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