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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18 F-JNJ-64413739, a PET Radioligand for P2X7 Receptors

Journal of Nuclear Medicine, 2019-08, Vol.60 (8), p.1154-1159

2019

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Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias

Circulation. Arrhythmia and electrophysiology, 2015-12, Vol.Publish Ahead of Print (6), p.1472-1480

2015

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Inhibition of the active lymph pump by flow in rat mesenteric lymphatics and thoracic duct

The Journal of physiology, 2002-05, Vol.540 (3), p.1023-1037

2002

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Dual Effect of Adenosine A1 Receptor Activation on Renal O2 Consumption

Journal of cellular physiology, 2015-12, Vol.230 (12), p.3093-3104

2015

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(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

British journal of pharmacology, 2006-12, Vol.149 (8), p.1013-1021

2006

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Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonist

The Journal of pharmacology and experimental therapeutics, 2002-03, Vol.300 (3), p.1122

2002

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Faster O2 uptake kinetics in canine skeletal muscle in situ after acute creatine kinase inhibition

The Journal of physiology, 2011-01, Vol.589 (1), p.221-233

2011

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Quantification of myoglobin deoxygenation and intracellular partial pressure of O2 during muscle contraction during haemoglobin‐free medium perfusion

Experimental physiology, 2010-05, Vol.95 (5), p.630-640

2010

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Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post‐transcriptional regulation in the spontaneously hypertensive rat model of ADHD

Journal of neurochemistry, 2011-10, Vol.119 (1), p.240-250

2011

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Specific mechanism of use-dependent channel block of calcium-permeable AMPA receptors provides activity-dependent inhibition of glutamatergic neurotransmission

The Journal of physiology, 2011-04, Vol.589 (Pt 7), p.1587-1601

2011

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Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes

Drug metabolism letters, 2011-01, Vol.5 (1), p.6-16

2011

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Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner

Biochimica et biophysica acta, 2006-12, Vol.1761 (12), p.1489-1497

2006

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Inhalation by Design: Novel Tertiary Amine Muscarinic M3 Receptor Antagonists with Slow Off-Rate Binding Kinetics for Inhaled Once-Daily Treatment of Chronic Obstructive Pulmonary Disease

Journal of medicinal chemistry, 2011-10, Vol.54 (19), p.6888-6904

2011

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Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

The Journal of pharmacology and experimental therapeutics, 2000-05, Vol.293 (2), p.444

2000

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Metabolism in Vitro and in Vivo of the DNA Base Adduct, M1G

Chemical research in toxicology, 2007-03, Vol.20 (3), p.550-557

2007

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Mechanistic Differences of Various AT1-Receptor Blockers in Isolated Vessels of Different Origin

Hypertension (Dallas, Tex. 1979), 1999-06, Vol.33 (6), p.1406-1413

1999

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Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes

Biophysical journal, 1995-04, Vol.68 (4), p.1453-1460

1995

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Heat shock protein 90 and tyrosine kinase regulate eNOS NO{middle dot} generation but not NO{middle dot} bioactivity

American journal of physiology. Heart and circulatory physiology, 2004-02, Vol.286 (2), p.H561-H569

2004

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Inhibitory Transmission in Locus Coeruleus Neurons Expressing GABAA Receptor Epsilon Subunit Has a Number of Unique Properties

Journal of neurophysiology, 2009-10, Vol.102 (4), p.2312-2325

2009

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Real-time assessment of Krebs cycle metabolism using hyperpolarized ¹³C magnetic resonance spectroscopy

The FASEB journal, 2009-08, Vol.23 (8), p.2529-2538

2009

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Inhibitory Effects of Ruta graveolens L. Extract on Guinea Pig Liver Aldehyde Oxidase

Chemical and Pharmaceutical Bulletin, 2006, Vol.54(1), pp.9-13

2006

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Different pharmacological properties of the optical isomers of MN9202, a novel 1,4-dihydropyridine Ca+ channel modulator, in rat ventricular myocytes

Clinical and experimental pharmacology & physiology, 2010-08, Vol.37 (8), p.817-825

2010

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Temperature-dependence of L-type Ca(2+) channel current in atrial myocytes from rainbow trout

Journal of experimental biology, 2000-09, Vol.203 (Pt 18), p.2771-2780

2000

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An adenosine derivative compound, IFC305, reverses fibrosis and alters gene expression in a pre-established CCl(4)-induced rat cirrhosis

The international journal of biochemistry & cell biology, 2010-02, Vol.42 (2), p.287-296

2010

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Mouse Group X Secretory Phospholipase A2 Induces a Potent Release of Arachidonic Acid from Spleen Cells and Acts as a Ligand for the Phospholipase A2 Receptor

Archives of biochemistry and biophysics, 2000-09, Vol.381 (1), p.31-42

2000

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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18 F-JNJ-64413739, a PET Radioligand for P2X7 Receptors

Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias

Inhibition of the active lymph pump by flow in rat mesenteric lymphatics and thoracic duct

Dual Effect of Adenosine A1 Receptor Activation on Renal O2 Consumption

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonist

Faster O2 uptake kinetics in canine skeletal muscle in situ after acute creatine kinase inhibition

Quantification of myoglobin deoxygenation and intracellular partial pressure of O2 during muscle contraction during haemoglobin‐free medium perfusion

Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post‐transcriptional regulation in the spontaneously hypertensive rat model of ADHD

Specific mechanism of use-dependent channel block of calcium-permeable AMPA receptors provides activity-dependent inhibition of glutamatergic neurotransmission

Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes

Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner

Inhalation by Design: Novel Tertiary Amine Muscarinic M3 Receptor Antagonists with Slow Off-Rate Binding Kinetics for Inhaled Once-Daily Treatment of Chronic Obstructive Pulmonary Disease

Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

Metabolism in Vitro and in Vivo of the DNA Base Adduct, M1G

Mechanistic Differences of Various AT1-Receptor Blockers in Isolated Vessels of Different Origin

Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes

Heat shock protein 90 and tyrosine kinase regulate eNOS NO{middle dot} generation but not NO{middle dot} bioactivity

Inhibitory Transmission in Locus Coeruleus Neurons Expressing GABAA Receptor Epsilon Subunit Has a Number of Unique Properties

Real-time assessment of Krebs cycle metabolism using hyperpolarized ¹³C magnetic resonance spectroscopy

Inhibitory Effects of Ruta graveolens L. Extract on Guinea Pig Liver Aldehyde Oxidase

Different pharmacological properties of the optical isomers of MN9202, a novel 1,4-dihydropyridine Ca+ channel modulator, in rat ventricular myocytes

Temperature-dependence of L-type Ca(2+) channel current in atrial myocytes from rainbow trout

An adenosine derivative compound, IFC305, reverses fibrosis and alters gene expression in a pre-established CCl(4)-induced rat cirrhosis

Mouse Group X Secretory Phospholipase A2 Induces a Potent Release of Arachidonic Acid from Spleen Cells and Acts as a Ligand for the Phospholipase A2 Receptor

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