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Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies

Critical care (London, England), 2024-02, Vol.28 (1), p.49-49, Article 49

2024

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Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Journal of antimicrobial chemotherapy, 2024-02, Vol.79 (2), p.429-442

2024

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Convalescent Plasma for Covid-19–Induced ARDS

The New England journal of medicine, 2024-01, Vol.390 (4), p.384-386

2024

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Convalescent Plasma for Covid-19-Induced ARDS. Reply

The New England journal of medicine, 2024-01, Vol.390 (4), p.386-386

2024

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Optimized Antibiotic Management of Critically Ill Patients with Severe Pneumonia Following Multiplex Polymerase Chain Reaction Testing: A Prospective Clinical Exploratory Trial

Antibiotics (Basel), 2024-01, Vol.13 (1), p.67

2024

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Inhaled drug delivery: a randomized study in intubated patients with healthy lungs

Annals of intensive care, 2023-12, Vol.13 (1), p.125-125, Article 125

2023

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Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial

The lancet respiratory medicine, 2023-10, Vol.11 (10), p.894-904

2023

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Dexamethasone Modulates the Cytokine Response but Not COVID-19-Induced Coagulopathy in Critically Ill

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7278

2023

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Profile of liver cholestatic biomarkers following prolonged ketamine administration in patients with COVID-19

BMC anesthesiology, 2023-02, Vol.23 (1), p.44-44, Article 44

2023

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Circulating dipeptidyl peptidase 3 and bio-adrenomedullin levels are associated with impaired outcomes in critically ill COVID-19 patients: a prospective international multicentre study

ERJ open research, 2023-01, Vol.9 (1), p.342

2023

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Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial

Frontiers in medicine, 2022-12, Vol.9, p.1058235-1058235

2022

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Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors

Critical care (London, England), 2022-10, Vol.26 (1), p.1-307, Article 307

2022

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Binding of temocillin to plasma proteins in vitro and in vivo: the importance of plasma protein levels in different populations and of co-medications

Journal of antimicrobial chemotherapy, 2022-09, Vol.77 (10), p.2742-2753

2022

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Opportunities for improved clinical trial designs in acute respiratory distress syndrome

The lancet respiratory medicine, 2022-09, Vol.10 (9), p.916-924

2022

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Pharmacokinetic profiles of intravenous versus subcutaneous administration of low molecular weight heparin for thromboprophylaxis in critically ill patients: A randomized controlled trial

Journal of critical care, 2022-08, Vol.70, p.154029-154029, Article 154029

2022

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NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study

Biomolecules (Basel, Switzerland), 2022-07, Vol.12 (8), p.1038

2022

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Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study

Journal of clinical microbiology, 2022-07, Vol.60 (7), p.e0034722-e0034722

2022

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Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

Antibiotics (Basel), 2022-07, Vol.11 (7), p.898

2022

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Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19

The lancet respiratory medicine, 2022-07, Vol.10 (7), p.700-714

2022

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Urine metabolomics links dysregulation of the tryptophan-kynurenine pathway to inflammation and severity of COVID-19

Scientific reports, 2022-06, Vol.12 (1), p.9959-9959, Article 9959

2022

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Improving the management of severe acute pancreatitis: The new guidelines from the French Society of Anaesthesia and Intensive Care Medicine

Anaesthesia critical care & pain medicine, 2022-06, Vol.41 (3), p.101103-101103, Article 101103

2022

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Early Corticosteroid Therapy May Increase Ventilator-Associated Lower Respiratory Tract Infection in Critically Ill Patients with COVID-19: A Multicenter Retrospective Cohort Study

Microorganisms (Basel), 2022-05, Vol.10 (5), p.984

2022

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Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Convalescent Plasma for Covid-19–Induced ARDS

Convalescent Plasma for Covid-19-Induced ARDS. Reply

Optimized Antibiotic Management of Critically Ill Patients with Severe Pneumonia Following Multiplex Polymerase Chain Reaction Testing: A Prospective Clinical Exploratory Trial

Inhaled drug delivery: a randomized study in intubated patients with healthy lungs

Convalescent Plasma for Covid-19–Induced ARDS in Mechanically Ventilated Patients

Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial

Evaluation of the efficacy and safety of TREM-1 inhibition with nangibotide in patients with COVID-19 receiving respiratory support: the ESSENTIAL randomised, double-blind trial

Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury

Dexamethasone Modulates the Cytokine Response but Not COVID-19-Induced Coagulopathy in Critically Ill

Profile of liver cholestatic biomarkers following prolonged ketamine administration in patients with COVID-19

Circulating dipeptidyl peptidase 3 and bio-adrenomedullin levels are associated with impaired outcomes in critically ill COVID-19 patients: a prospective international multicentre study

Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial

Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors

Binding of temocillin to plasma proteins in vitro and in vivo: the importance of plasma protein levels in different populations and of co-medications

Opportunities for improved clinical trial designs in acute respiratory distress syndrome

Pharmacokinetic profiles of intravenous versus subcutaneous administration of low molecular weight heparin for thromboprophylaxis in critically ill patients: A randomized controlled trial

NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study

Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study

Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19

Urine metabolomics links dysregulation of the tryptophan-kynurenine pathway to inflammation and severity of COVID-19

Improving the management of severe acute pancreatitis: The new guidelines from the French Society of Anaesthesia and Intensive Care Medicine

Early Corticosteroid Therapy May Increase Ventilator-Associated Lower Respiratory Tract Infection in Critically Ill Patients with COVID-19: A Multicenter Retrospective Cohort Study

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