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Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

Nature communications, 2021-06, Vol.12 (1), p.3742-16, Article 3742

2021

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LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

Cancer cell, 2012-06, Vol.21 (6), p.751-764

2012

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Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer

Scientific reports, 2022-12, Vol.12 (1), p.21248-21248, Article 21248

2022

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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

Genome biology, 2013-11, Vol.14 (11), p.R125-R125, Article R125

2013

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Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver

Genetics (Austin), 2012-10, Vol.192 (2), p.385-396

2012

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The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor

Disease models & mechanisms, 2019-07, Vol.12 (7)

2019

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Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers

Disease models & mechanisms, 2016-07, Vol.9 (7), p.749-757

2016

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Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy

NPJ breast cancer, 2024-03, Vol.10 (1), p.20-20, Article 20

2024

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Conditional Loss of ErbB3 Delays Mammary Gland Hyperplasia Induced by Mutant PIK3CA without Affecting Mammary Tumor Latency, Gene Expression, or Signaling

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.4075-4085

2013

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Both noncoding and protein-coding RNAs contribute to gene expression evolution in the primate brain

Genome biology and evolution, 2010-01, Vol.2, p.67-79

2010

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A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues

PloS one, 2010-09, Vol.5 (9), p.e12545

2010

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Oncogenic PI3K Mutations Lead to NF-κB―Dependent Cytokine Expression following Growth Factor Deprivation

Cancer research (Chicago, Ill.), 2012-07, Vol.72 (13), p.3260-3269

2012

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Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models

Clinical cancer research, 2012-10, Vol.18 (19), p.5290-5303

2012

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Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy

Breast cancer research and treatment, 2015-01, Vol.149 (2), p.425-437

2015

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A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

Breast cancer research and treatment, 2019-02, Vol.174 (1), p.143-155

2019

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Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis

Clinical & experimental metastasis, 2014-01, Vol.31 (1), p.33-45

2014

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Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes

Current Protocols in Pharmacology, 2016-03, Vol.72 (1), p.14.38.1-14.38.11

2016

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c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression

Oncotarget, 2015-05, Vol.6 (14), p.11863-11881

2015

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A Potential Role for Glucose Transporters in the Evolution of Human Brain Size

Brain, behavior and evolution, 2011-11, Vol.78 (4), p.315-326

2011

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Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution

Journal of human evolution, 2011-02, Vol.60 (2), p.205-212

2011

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Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential

Oncogene, 2015-12, Vol.34 (49), p.5997-6006

2015

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Abstract 3306: Wnt pathway dynamics in breast cancer progression

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3306-3306

2016

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Abstract 2307: Targeted agents and chemotherapeutic treatments of genetically engineered Basal-like breast cancer mouse model

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2307-2307

2015

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Abstract PO1-15-10: Lower pre-treatment B-cell gene expression signatures correspond with improved overall survival with palbociclib + endocrine therapy in HR+/HER2- metastatic breast cancer: a biomarker analysis from the GEICAM/2013-02 PEARL trial

Cancer research (Chicago, Ill.), 2024-05, Vol.84 (9_Supplement), p.PO1-15-10-PO1-15-10

2024

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Abstract LB-103: Conditional loss of ErbB3 delays mammary gland hyperplasias induced by mutant PIK3CA in transgenic mice, but does not affect mammary tumor latency, gene expression or signaling

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.LB-103-LB-103

2012

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Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver

The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor

Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers

Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy

Conditional Loss of ErbB3 Delays Mammary Gland Hyperplasia Induced by Mutant PIK3CA without Affecting Mammary Tumor Latency, Gene Expression, or Signaling

Both noncoding and protein-coding RNAs contribute to gene expression evolution in the primate brain

A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues

Oncogenic PI3K Mutations Lead to NF-κB―Dependent Cytokine Expression following Growth Factor Deprivation

Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models

Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy

A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis

Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes

c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression

A Potential Role for Glucose Transporters in the Evolution of Human Brain Size

Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution

Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential

Abstract 3306: Wnt pathway dynamics in breast cancer progression

Abstract 2307: Targeted agents and chemotherapeutic treatments of genetically engineered Basal-like breast cancer mouse model

Abstract PO1-15-10: Lower pre-treatment B-cell gene expression signatures correspond with improved overall survival with palbociclib + endocrine therapy in HR+/HER2- metastatic breast cancer: a biomarker analysis from the GEICAM/2013-02 PEARL trial

Abstract LB-103: Conditional loss of ErbB3 delays mammary gland hyperplasias induced by mutant PIK3CA in transgenic mice, but does not affect mammary tumor latency, gene expression or signaling

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