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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6694-6699

2012

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The discovery of CCR3/H1 dual antagonists with reduced hERG risk

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6688-6693

2012

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Host―microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Nature (London), 2012-11, Vol.491 (7422), p.119-124

2012

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Lymph Node Metastasis in Intermediate-Risk Penile Squamous Cell Cancer: A Two-Centre Experience

European urology, 2010-04, Vol.57 (4), p.688-692

2010

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Long-Acting Risperidone and Oral Antipsychotics in Unstable Schizophrenia

The New England journal of medicine, 2011-03, Vol.364 (9), p.842-851

2011

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Population-based Analysis of Alzheimer’s Disease Risk Alleles Implicates Genetic Interactions

Biological psychiatry (1969), 2014-05, Vol.75 (9), p.732-737

2014

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Clinic-Based Outpatient Palliative Care Before Hospice Is Associated With Longer Hospice Length of Service

Journal of pain and symptom management, 2014-10, Vol.48 (4), p.532-539

2014

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Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy

Cancer, 2007-09, Vol.110 (6), p.1281-1286

2007

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Cortical Thickness Is Influenced by Regionally Specific Genetic Factors

Biological psychiatry (1969), 2010-03, Vol.67 (5), p.493-499

2010

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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Nature genetics, 2008-05, Vol.40 (5), p.638-645

2008

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Preoperative lymph node staging of early‐stage cervical carcinoma by [18F]‐fluoro‐2‐deoxy‐D‐glucose–positron emission tomography

Cancer, 2005-12, Vol.104 (11), p.2484-2491

2005

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Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

Cardiovascular research, 2011-09, Vol.91 (4), p.694-702

2011

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Radiofrequency ablation of pulmonary malignant tumors in nonsurgical candidates

The Journal of thoracic and cardiovascular surgery, 2003-04, Vol.125 (4), p.929-937

2003

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Cervical carcinoma in the elderly: An analysis of patterns of care and outcome

Cancer, 2005, Vol.103 (1), p.85-91

2005

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Management of pediatric trauma

Pediatrics (Evanston), 2008-04, Vol.121 (4), p.849

2008

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Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

Journal of medicinal chemistry, 2006-08, Vol.49 (16), p.4981-4991

2006

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Correlation of gene expression and contaminant concentrations in wild largescale suckers: A field-based study : Foodweb Transfer, Sediment Transport, and Biological Effects of Emerging and Legacy Organic Contaminants in the Lower Columbia River, Oregon, and Washington, USA

The Science of the total environment, 2014, Vol.484, p.379-389

2014

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Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm

Psychopharmacologia, 2011-06, Vol.215 (4), p.697-707

2011

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Predictors of serum testosterone and DHEAS in African-American men

International journal of andrology, 2008-02, Vol.31 (1), p.50-59

2008

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A glial-specific, repressible, adenovirus vector for brain tumor gene therapy

Cancer research (Chicago, Ill.), 1998-08, Vol.58 (16), p.3504-3507

1998

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Lymphomatoid papulosis associated with Ki‐1‐positive anaplastic large cell lymphoma. A report of two cases and a review of the literature

Cancer, 1994-12, Vol.74 (11), p.3051-3058

1994

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Diagnosis of Metastatic Malignant Melanoma by Fine Needle Aspiration Biopsy: A Clinical and Pathologic Correlation of 298 Cases

JNCI : Journal of the National Cancer Institute, 1986-11, Vol.77 (5), p.1013-1021

1986

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Prevention and Treatment of Hypertension Study (PATHS): effects of an alcohol treatment program on blood pressure

Archives of internal medicine (1960), 1998-06, Vol.158 (11), p.1197

1998

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p53 mutations, O6‐alkylguanine DNA alkyltransferase activity, and sensitivity to procarbazine in human brain tumors

Cancer, 1995-03, Vol.75 (6), p.1339-1342

1995

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A new respiratory quinone, 2‐methyl‐3‐VI,VII‐tetrahydroheptaprenyl‐1,4‐naphthoquinone isolated from Thermoleophilum album

FEMS microbiology letters, 1986-04, Vol.34 (2), p.167-171

1986

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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092

The discovery of CCR3/H1 dual antagonists with reduced hERG risk

Host―microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Lymph Node Metastasis in Intermediate-Risk Penile Squamous Cell Cancer: A Two-Centre Experience

Long-Acting Risperidone and Oral Antipsychotics in Unstable Schizophrenia

Population-based Analysis of Alzheimer’s Disease Risk Alleles Implicates Genetic Interactions

Clinic-Based Outpatient Palliative Care Before Hospice Is Associated With Longer Hospice Length of Service

Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy

Cortical Thickness Is Influenced by Regionally Specific Genetic Factors

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Preoperative lymph node staging of early‐stage cervical carcinoma by [18F]‐fluoro‐2‐deoxy‐D‐glucose–positron emission tomography

Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

Radiofrequency ablation of pulmonary malignant tumors in nonsurgical candidates

Cervical carcinoma in the elderly: An analysis of patterns of care and outcome

Management of pediatric trauma

Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

Correlation of gene expression and contaminant concentrations in wild largescale suckers: A field-based study : Foodweb Transfer, Sediment Transport, and Biological Effects of Emerging and Legacy Organic Contaminants in the Lower Columbia River, Oregon, and Washington, USA

Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm

Predictors of serum testosterone and DHEAS in African-American men

A glial-specific, repressible, adenovirus vector for brain tumor gene therapy

Lymphomatoid papulosis associated with Ki‐1‐positive anaplastic large cell lymphoma. A report of two cases and a review of the literature

Diagnosis of Metastatic Malignant Melanoma by Fine Needle Aspiration Biopsy: A Clinical and Pathologic Correlation of 298 Cases

Prevention and Treatment of Hypertension Study (PATHS): effects of an alcohol treatment program on blood pressure

p53 mutations, O6‐alkylguanine DNA alkyltransferase activity, and sensitivity to procarbazine in human brain tumors

A new respiratory quinone, 2‐methyl‐3‐VI,VII‐tetrahydroheptaprenyl‐1,4‐naphthoquinone isolated from Thermoleophilum album

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