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An NMR View of Protein Dynamics in Health and Disease

Annual review of biophysics, 2019-05, Vol.48 (1), p.297-319

2019

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Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles

eLife, 2017-07, Vol.6

2017

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Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer

Journal of biomolecular NMR, 2017-04, Vol.67 (4), p.243-271

2017

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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions

eLife, 2018-02, Vol.7

2018

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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

Journal of Magnetic Resonance Open, 2022-06, Vol.10-11, p.100034-100034, Article 100034

2022

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Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways

eLife, 2015-06, Vol.4, p.e07296-e07296

2015

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Metamorphic proteins: the Janus proteins of structural biology

Open biology, 2021-04, Vol.11 (4), p.210012-210012

2021

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Quantification of Entropic Excluded Volume Effects Driving Crowding-Induced Collapse and Folding of a Disordered Protein

The journal of physical chemistry letters, 2022-04, Vol.13 (13), p.3112-3120

2022

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Sensory Feedback Myoelectric Arm

International Journal of Mechanical and Production Engineering Research and Development, 2020, Vol.10 (3), p.10925-10936

Chandra Sekhar Ashok et al, Chandra Sekhar Ashok et al

2020

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Transient excited states of the metamorphic protein Mad2 and their implications for function

Proteins, structure, function, and bioinformatics, 2024-01

2024

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Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts

Biochemistry (Easton), 2016-03, Vol.55 (9), p.1346-1361

2016

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Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy

Biochemistry (Easton), 2020-01, Vol.59 (1), p.57-73

2020

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Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR

Journal of the American Chemical Society, 2024-02, Vol.146 (6), p.3825-3835

2024

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Studying micro to millisecond protein dynamics using simple amide 15N CEST experiments supplemented with major-state R2 and visible peak-position constraints

Journal of biomolecular NMR, 2023-08, Vol.77 (4), p.165-181

2023

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1H-Detected 13C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR

Journal of the American Chemical Society, 2011-06, Vol.133 (21), p.8062-8065

2011

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Measuring radiofrequency fields in NMR spectroscopy using offset-dependent nutation profiles

Journal of magnetic resonance (1997), 2021-09, Vol.330, p.107032-107032, Article 107032

2021

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A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations

The journal of physical chemistry letters, 2017-10, Vol.8 (19), p.4779-4784

2017

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Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective

Proteins, structure, function, and bioinformatics, 2024-08

2024

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Self-Assembly of Human Profilin‑1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy

Biochemistry (Easton), 2017-02, Vol.56 (5), p.692-703

2017

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Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch

Methods (San Diego, Calif.), 2023-10, Vol.218, p.198-209

2023

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Studying micro to millisecond protein dynamics using simple amide 15 N CEST experiments supplemented with major-state R 2 and visible peak-position constraints

Journal of biomolecular NMR, 2023-08, Vol.77 (4), p.165

2023

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Structure and carbohydrate recognition by the non-mitogenic lectin horcolin

Biochemistry (Easton), 2022-02, Vol.61 (6), p.464-478

2022

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A finely balanced order-disorder equilibrium sculpts the folding-binding landscape of an antibiotic sequestering protein

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (20), p.e2318855121

2024

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Structure and Carbohydrate Recognition by the Nonmitogenic Lectin Horcolin

Biochemistry (Easton), 2022-03, Vol.61 (6), p.464-478

2022

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Conformational heterogeneity in the Hsp70 chaperone‐substrate ensemble identified from analysis of NMR‐detected titration data

Protein science, 2017-11, Vol.26 (11), p.2207-2220

2017

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An NMR View of Protein Dynamics in Health and Disease

Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles

Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer

Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions

Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways

Metamorphic proteins: the Janus proteins of structural biology

Quantification of Entropic Excluded Volume Effects Driving Crowding-Induced Collapse and Folding of a Disordered Protein

Sensory Feedback Myoelectric Arm

Transient excited states of the metamorphic protein Mad2 and their implications for function

Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts

Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy

Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR

Studying micro to millisecond protein dynamics using simple amide 15N CEST experiments supplemented with major-state R2 and visible peak-position constraints

1H-Detected 13C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR

Measuring radiofrequency fields in NMR spectroscopy using offset-dependent nutation profiles

A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations

Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective

Self-Assembly of Human Profilin‑1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy

Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch

Studying micro to millisecond protein dynamics using simple amide 15 N CEST experiments supplemented with major-state R 2 and visible peak-position constraints

Structure and carbohydrate recognition by the non-mitogenic lectin horcolin

A finely balanced order-disorder equilibrium sculpts the folding-binding landscape of an antibiotic sequestering protein

Structure and Carbohydrate Recognition by the Nonmitogenic Lectin Horcolin

Conformational heterogeneity in the Hsp70 chaperone‐substrate ensemble identified from analysis of NMR‐detected titration data

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