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Tweaking the catalytic efficiency of the CFTR ion channel

The Journal of general physiology, 2023-05, Vol.155 (5), p.1

McCarty, Nael A

2023

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The "new normal": Adapting doctoral trainee career preparation for broad career paths in science

PloS one, 2017-05, Vol.12 (5), p.e0177035-e0177035

2017

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Breathe-Your immune system is counting on it

The Journal of experimental medicine, 2021-04, Vol.218 (4)

McCarty, Nael A

2021

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Modeling the conformational changes underlying channel opening in CFTR

PloS one, 2013-09, Vol.8 (9), p.e74574-e74574

2013

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Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis

PLoS genetics, 2014-07, Vol.10 (7), p.e1004376-e1004376

2014

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The molecular evolution of function in the CFTR chloride channel

The Journal of general physiology, 2021-12, Vol.153 (12), p.1

2021

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An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

Developmental cell, 2019-11, Vol.51 (4), p.421-430.e3

2019

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Murine and human CFTR exhibit different sensitivities to CFTR potentiators

American journal of physiology. Lung cellular and molecular physiology, 2015-10, Vol.309 (7), p.L687-L699

2015

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Electrophysiological Approaches for the Study of Ion Channel Function

Methods in molecular biology (Clifton, N.J.), 2021-01, Vol.2302, p.49

2021

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Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Frontiers in pharmacology, 2024-02, Vol.15, p.1363456-1363456

2024

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A longitudinal analysis of chronic MRSA and Pseudomonas aeruginosa co-infection in cystic fibrosis: A single-center study

Journal of cystic fibrosis, 2016-05, Vol.15 (3), p.350-356

2016

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Correction: The "new normal": Adapting doctoral trainee career preparation for broad career paths in science

PloS one, 2017-07, Vol.12 (7), p.e0181294-e0181294

2017

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Junctional abnormalities in human airway epithelial cells expressing F508del CFTR

American journal of physiology. Lung cellular and molecular physiology, 2015-09, Vol.309 (5), p.L475-L487

2015

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Exacerbation-prone pediatric asthma is associated with arginine, lysine, and methionine pathway alterations

Journal of allergy and clinical immunology, 2023-01, Vol.151 (1), p.118-127.e10

2023

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Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator

American journal of physiology. Lung cellular and molecular physiology, 2016-03, Vol.310 (5), p.L403-L414

2016

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VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level

Scientific reports, 2019-09, Vol.9 (1), p.13460-17, Article 13460

2019

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Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics

Journal of proteome research, 2020-01, Vol.19 (1), p.144-152

2020

Volltextzugriff (PDF)

Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study

Journal of proteome research, 2017-02, Vol.16 (2), p.550-558

2017

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Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane Conductance Regulator Protein

Journal of chemical information and modeling, 2017-08, Vol.57 (8), p.1932-1946

2017

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Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Channel Activity

Frontiers in physiology, 2021-06, Vol.12, p.652513-652513

2021

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The bidirectional relationship between CFTR and lipids

Communications biology, 2020-04, Vol.3 (1), p.179, Article 179

2020

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Two Salt Bridges Differentially Contribute to the Maintenance of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel Function

The Journal of biological chemistry, 2013-07, Vol.288 (28), p.20758-20767

2013

Volltextzugriff (PDF)

Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner

American journal of physiology. Lung cellular and molecular physiology, 2017-05, Vol.312 (5), p.L688-L702

2017

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Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes

American journal of physiology. Lung cellular and molecular physiology, 2014-01, Vol.306 (1), p.L43-L49

2014

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Bacteriophage‐Loaded Poly(lactic‐co‐glycolic acid) Microparticles Mitigate Staphylococcus aureus Infection and Cocultures of Staphylococcus aureus and Pseudomonas aeruginosa

Advanced healthcare materials, 2022-05, Vol.11 (10), p.e2102539-n/a

2022

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Tweaking the catalytic efficiency of the CFTR ion channel

The "new normal": Adapting doctoral trainee career preparation for broad career paths in science

Breathe-Your immune system is counting on it

Modeling the conformational changes underlying channel opening in CFTR

Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis

The molecular evolution of function in the CFTR chloride channel

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

Murine and human CFTR exhibit different sensitivities to CFTR potentiators

Electrophysiological Approaches for the Study of Ion Channel Function

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

A longitudinal analysis of chronic MRSA and Pseudomonas aeruginosa co-infection in cystic fibrosis: A single-center study

Correction: The "new normal": Adapting doctoral trainee career preparation for broad career paths in science

Junctional abnormalities in human airway epithelial cells expressing F508del CFTR

Exacerbation-prone pediatric asthma is associated with arginine, lysine, and methionine pathway alterations

Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level

Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics

Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study

Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane Conductance Regulator Protein

Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Channel Activity

The bidirectional relationship between CFTR and lipids

Two Salt Bridges Differentially Contribute to the Maintenance of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel Function

Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner

Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes

Bacteriophage‐Loaded Poly(lactic‐co‐glycolic acid) Microparticles Mitigate Staphylococcus aureus Infection and Cocultures of Staphylococcus aureus and Pseudomonas aeruginosa

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