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Seroconversion rates among health care workers exposed to hepatitis C virus–contaminated body fluids: The University of Pittsburgh 13-year experience

American journal of infection control, 2017-09, Vol.45 (9), p.1001-1005

2017

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Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

Scientific reports, 2018-07, Vol.8 (1), p.10479-10, Article 10479

2018

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Seroconversion rate among health care workers exposed to HIV-contaminated body fluids: The University of Pittsburgh 13-year experience

American journal of infection control, 2017-08, Vol.45 (8), p.896-900

2017

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Systemic Inhibition of Transforming Growth Factor-β in Glioma-Bearing Mice Improves the Therapeutic Efficacy of Glioma-Associated Antigen Peptide Vaccines

Clinical cancer research, 2009-11, Vol.15 (21), p.6551-6559

2009

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Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies

Molecular cancer therapeutics, 2015-09, Vol.14 (9), p.2081-2089

2015

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TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence

PloS one, 2011-09, Vol.6 (9), p.e25168-e25168

2011

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Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (18), p.8736-8741

2007

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Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation

Antibodies (Basel), 2017-11, Vol.6 (4), p.20

2017

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Self-reported influenza vaccination rates among health care workers in a large health system

American journal of infection control, 2008-10, Vol.36 (8), p.574-581

2008

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Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides

Journal of controlled release, 2015-12, Vol.220 (Pt B), p.660-670

2015

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Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (10), p.2686-2698

2017

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Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics

Journal of controlled release, 2016-08, Vol.236, p.100-116

2016

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Doxycycline Treatment for Lymphangioleiomyomatosis with Urinary Monitoring for MMPs

The New England journal of medicine, 2006-06, Vol.354 (24), p.2621-2622

2006

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Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR

Molecular cancer therapeutics, 2021-03, Vol.20 (3), p.541-552

2021

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A Diene‐Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels–Alder Reaction with Maleimide or Proximity‐Based Dimerization

Angewandte Chemie International Edition, 2019-06, Vol.58 (25), p.8489-8493

International ed. in English, 2019

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Establish the Habit: Influenza Vaccination for Health Care Personnel

Journal for healthcare quality, 2010-03, Vol.32 (2), p.35-42

2010

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Fractionated Dosing Improves Preclinical Therapeutic Index of Pyrrolobenzodiazepine-Containing Antibody Drug Conjugates

Clinical cancer research, 2017-10, Vol.23 (19), p.5858-5868

2017

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Structure–Cytotoxicity Relationships of Analogues of N 14-Desacetoxytubulysin H

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10781-10787

2016

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Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension

Bioconjugate chemistry, 2019-04, Vol.30 (4), p.1232-1243

2019

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TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression

Cancer research (Chicago, Ill.), 2012-09, Vol.72 (18), p.4840-4845

2012

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Abstract 76: Synthetic lethal targeting of BRCA mutant tumors with antibody linked pyrrolobenzodiazepine dimers

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.76-76

2017

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Improved Therapeutic Window in BRCA -mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition

Molecular cancer therapeutics, 2019-01, Vol.18 (1), p.89-99

2019

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A Reactive Antibody Platform for One-Step Production of Antibody–Drug Conjugates through a Diels–Alder Reaction with Maleimide

Bioconjugate chemistry, 2019-09, Vol.30 (9), p.2340-2348

2019

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Determining foot and ankle impairments by the AMA fifth edition guides

Foot and ankle clinics, 2002-06, Vol.7 (2), p.291-303

Harper, Jay D

2002

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Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers

European journal of medicinal chemistry, 2019-10, Vol.179, p.591-607

2019

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Seroconversion rates among health care workers exposed to hepatitis C virus–contaminated body fluids: The University of Pittsburgh 13-year experience

Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

Seroconversion rate among health care workers exposed to HIV-contaminated body fluids: The University of Pittsburgh 13-year experience

Systemic Inhibition of Transforming Growth Factor-β in Glioma-Bearing Mice Improves the Therapeutic Efficacy of Glioma-Associated Antigen Peptide Vaccines

Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies

TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence

Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24

Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation

Self-reported influenza vaccination rates among health care workers in a large health system

Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides

Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies

Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics

Doxycycline Treatment for Lymphangioleiomyomatosis with Urinary Monitoring for MMPs

Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR

A Diene‐Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels–Alder Reaction with Maleimide or Proximity‐Based Dimerization

Establish the Habit: Influenza Vaccination for Health Care Personnel

Fractionated Dosing Improves Preclinical Therapeutic Index of Pyrrolobenzodiazepine-Containing Antibody Drug Conjugates

Structure–Cytotoxicity Relationships of Analogues of N 14-Desacetoxytubulysin H

Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension

TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression

Abstract 76: Synthetic lethal targeting of BRCA mutant tumors with antibody linked pyrrolobenzodiazepine dimers

Improved Therapeutic Window in BRCA -mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition

A Reactive Antibody Platform for One-Step Production of Antibody–Drug Conjugates through a Diels–Alder Reaction with Maleimide

Determining foot and ankle impairments by the AMA fifth edition guides

Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers

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