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Notch signaling is activated by TLR stimulation and regulates macrophage functions

European journal of immunology, 2008-01, Vol.38 (1), p.174-183

2008

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Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

The Journal of neuroscience, 2010-05, Vol.30 (20), p.6862-6872

2010

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Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia

The Journal of experimental medicine, 2013-07, Vol.210 (7), p.1311-1329

2013

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Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells

Frontiers in immunology, 2014, Vol.5, p.54-54

2014

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Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

PloS one, 2010-05, Vol.5 (5), p.e10504

2010

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Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2808-2811

2013

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A convenient synthesis of ( Z)-4-hydroxy- N-desmethyltamoxifen (endoxifen)

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3036-3038

2010

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Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

The Journal of neuroscience, 2012-09, Vol.32 (38), p.13125-13136

2012

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Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

Tetrahedron letters, 2010-12, Vol.51 (49), p.6426-6428

2010

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Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.248-254

2006

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Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin

Biochimie, 2011-07, Vol.93 (7), p.1089-1101

2011

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Notch1 augments NF-κB activity by facilitating its nuclear retention

The EMBO journal, 2006-01, Vol.25 (1), p.129-138

2006

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Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2246-2255

2013

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Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme

The Journal of biological chemistry, 2006-10, Vol.281 (41), p.30471-30478

2006

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Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Nature immunology, 2005-07, Vol.6 (7), p.680-688

2005

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γ-Secretase Processing and Effects of γ-Secretase Inhibitors and Modulators on Long Aβ Peptides in Cells

The Journal of biological chemistry, 2014-02, Vol.289 (6), p.3276-3287

2014

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Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.4344-4353

2011

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Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes : NCCTG trial N01CC

Journal of clinical oncology, 2006-06, Vol.24 (18), p.2836-2841

2006

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A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6392-6395

2007

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NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

Frontiers in immunology, 2014, Vol.5, p.249-249

2014

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The role of NTS2 in the development of tolerance to NT69L in mouse models for hypothermia and thermal analgesia

Behavioural brain research, 2011-10, Vol.224 (2), p.344-349

2011

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A synthesis of the γ-secretase inhibitor BMS-708163

Tetrahedron letters, 2010-12, Vol.51 (50), p.6542-6544

2010

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Iothalamate Quantification by Tandem Mass Spectrometry to Measure Glomerular Filtration Rate

Clinical chemistry (Baltimore, Md.), 2010-04, Vol.56 (4), p.568-574

2010

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Hydrolysis of low concentrations of the acetylthiocholine analogs acetyl(homo)thiocholine and acetyl(nor)thiocholine by acetylcholinesterase may be limited by selective gating at the enzyme peripheral site

Chemico-biological interactions, 2013-03, Vol.203 (1), p.38-43

2013

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Design and Chemical Synthesis of a Magnetic Resonance Contrast Agent with Enhanced in Vitro Binding, High Blood−Brain Barrier Permeability, and in Vivo Targeting to Alzheimer's Disease Amyloid Plaques

Biochemistry (Easton), 2004-05, Vol.43 (20), p.6064-6075

2004

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Notch signaling is activated by TLR stimulation and regulates macrophage functions

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells

Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies

A convenient synthesis of ( Z)-4-hydroxy- N-desmethyltamoxifen (endoxifen)

Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin

Notch1 augments NF-κB activity by facilitating its nuclear retention

Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity

Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

γ-Secretase Processing and Effects of γ-Secretase Inhibitors and Modulators on Long Aβ Peptides in Cells

Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin

Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes : NCCTG trial N01CC

A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

The role of NTS2 in the development of tolerance to NT69L in mouse models for hypothermia and thermal analgesia

A synthesis of the γ-secretase inhibitor BMS-708163

Iothalamate Quantification by Tandem Mass Spectrometry to Measure Glomerular Filtration Rate

Hydrolysis of low concentrations of the acetylthiocholine analogs acetyl(homo)thiocholine and acetyl(nor)thiocholine by acetylcholinesterase may be limited by selective gating at the enzyme peripheral site

Design and Chemical Synthesis of a Magnetic Resonance Contrast Agent with Enhanced in Vitro Binding, High Blood−Brain Barrier Permeability, and in Vivo Targeting to Alzheimer's Disease Amyloid Plaques

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