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Knocking 'em Dead: Pore-Forming Proteins in Immune Defense

Annual review of immunology, 2020-04, Vol.38, p.455

2020

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Cryo-EM structure of the gasdermin A3 membrane pore

Nature (London), 2018-05, Vol.557 (7703), p.62-67

2018

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Nature (London), 2016-07, Vol.535 (7610), p.153-158

2016

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Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis

Brain, behavior, and immunity, 2019-08, Vol.80, p.859-870

2019

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Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis

Nature (London), 2022-02, Vol.602 (7897), p.496-502

2022

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Caspase‐1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia

CNS neuroscience & therapeutics, 2020-09, Vol.26 (9), p.925-939

2020

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Inhibition of hepatitis B virus by the CRISPR/Cas9 system via targeting the conserved regions of the viral genome

Journal of general virology, 2015-08, Vol.96 (8), p.2252-2261

2015

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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Nature immunology, 2020-07, Vol.21 (7), p.736

2020

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Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti

Pest management science, 2017-05, Vol.73 (5), p.953-959

2017

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The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING

Immunity (Cambridge, Mass.), 2014-12, Vol.41 (6), p.919-933

2014

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Juvenile hormone regulates the photoperiodic plasticity of elytra coloration in the ladybird Harmonia axyridis

Molecular ecology, 2023-06, Vol.32 (11), p.2884-2897

2023

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TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation

Scientific reports, 2016-06, Vol.6 (1), p.28188-28188, Article 28188

2016

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Paternal Psychological Stress Reprograms Hepatic Gluconeogenesis in Offspring

Cell metabolism, 2016-04, Vol.23 (4), p.735-743

2016

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Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation

International immunopharmacology, 2020-08, Vol.85, p.106662, Article 106662

2020

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Microwave-assisted synthesis of carbon nanodots through an eggshell membrane and their fluorescent application

Analyst (London), 2012-11, Vol.137 (22), p.5392-5397

2012

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Synthesis, nematocidal activity and SAR study of novel difluoromethylpyrazole carboxamide derivatives containing flexible alkyl chain moieties

European journal of medicinal chemistry, 2017-01, Vol.125, p.881-889

2017

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Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter

Cell research, 2014-08, Vol.24 (11), p.1374-1377

2014

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Mitochondrial genome of the nematode endoparasitic fungus Hirsutella vermicola reveals a high level of synteny in the family Ophiocordycipitaceae

Applied microbiology and biotechnology, 2017-04, Vol.101 (8), p.3295-3304

2017

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Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice

Food & function, 2021-11, Vol.12 (23), p.12142-12158

2021

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Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication

PLoS pathogens, 2023-03, Vol.19 (3), p.e1011295-e1011295

2023

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BSA-templated MnO2 nanoparticles as both peroxidase and oxidase mimics

Analyst (London), 2012-10, Vol.137 (19), p.4552-4558

2012

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Synthesis, nematocidal activity and docking study of novel chiral 1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide derivatives

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (15), p.3626-3628

2016

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Assembly and Regulation of CRL Ubiquitin Ligases

Advances in experimental medicine and biology, 2020-01, Vol.1217, p.33-46

2020

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Replication and virulence in pigs of the first African swine fever virus isolated in China

Emerging microbes & infections, 2019-01, Vol.8 (1), p.438-447

2019

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Rhizoma Bletillae polysaccharide elicits hemostatic effects in platelet-rich plasma by activating adenosine diphosphate receptor signaling pathway

Biomedicine & pharmacotherapy, 2020-10, Vol.130, p.110537, Article 110537

2020

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Knocking 'em Dead: Pore-Forming Proteins in Immune Defense

Cryo-EM structure of the gasdermin A3 membrane pore

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis

Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis

Caspase‐1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia

Inhibition of hepatitis B virus by the CRISPR/Cas9 system via targeting the conserved regions of the viral genome

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti

The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING

Juvenile hormone regulates the photoperiodic plasticity of elytra coloration in the ladybird Harmonia axyridis

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation

Paternal Psychological Stress Reprograms Hepatic Gluconeogenesis in Offspring

Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation

Microwave-assisted synthesis of carbon nanodots through an eggshell membrane and their fluorescent application

Synthesis, nematocidal activity and SAR study of novel difluoromethylpyrazole carboxamide derivatives containing flexible alkyl chain moieties

Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter

Mitochondrial genome of the nematode endoparasitic fungus Hirsutella vermicola reveals a high level of synteny in the family Ophiocordycipitaceae

Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice

Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication

BSA-templated MnO2 nanoparticles as both peroxidase and oxidase mimics

Synthesis, nematocidal activity and docking study of novel chiral 1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide derivatives

Assembly and Regulation of CRL Ubiquitin Ligases

Replication and virulence in pigs of the first African swine fever virus isolated in China

Rhizoma Bletillae polysaccharide elicits hemostatic effects in platelet-rich plasma by activating adenosine diphosphate receptor signaling pathway

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