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The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals

European journal of pharmacology, 2015-07, Vol.759, p.3-13

2015

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Animal models of atherosclerosis

European journal of pharmacology, 2017-12, Vol.816, p.3-13

2017

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Resveratrol modulates Toxoplasma gondii infection induced liver injury by intervening in the HMGB1/TLR4/NF-κB signaling pathway

European journal of pharmacology, 2021-11, Vol.910, p.174497-174497, Article 174497

2021

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Rodent models for human diseases

European journal of pharmacology, 2015-07, Vol.759, p.84-89

Vandamme, Thierry F.

2015

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The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease

European journal of pharmacology, 2015-07, Vol.759, p.19-29

2015

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Ponatinib-induced ischemic stroke in larval zebrafish for drug screening

European journal of pharmacology, 2020-12, Vol.889, p.173292-173292, Article 173292

2020

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Macrophage M1/M2 polarization

European journal of pharmacology, 2020-06, Vol.877, p.173090-173090, Article 173090

2020

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Supplementation of taurine improves ionic homeostasis and mitochondrial function in the rats exhibiting post-traumatic stress disorder-like symptoms

European journal of pharmacology, 2021-10, Vol.908, p.174361, Article 174361

2021

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Preclinical experimental stress studies: Protocols, assessment and comparison

European journal of pharmacology, 2015-01, Vol.746, p.282-292

2015

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Dopamine-neurotransmission and nociception in zebrafish: An anti-nociceptive role of dopamine receptor drd2a

European journal of pharmacology, 2021-12, Vol.912, p.174517-174517, Article 174517

2021

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Experimental models of Parkinson's disease: Challenges and Opportunities

European journal of pharmacology, 2024-10, Vol.980, p.176819, Article 176819

2024

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Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer's disease

European journal of pharmacology, 2019-09, Vol.859, p.172524-172524, Article 172524

2019

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The olfactory bulbectomy model in mice and rat: One story or two tails?

European journal of pharmacology, 2015-04, Vol.753, p.105-113

2015

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The effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder

European journal of pharmacology, 2019-12, Vol.865, p.172751-172751, Article 172751

2019

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Dose-dependent opposite effects of nortriptyline on affective-like behavior in adolescent rats: Comparison with adult rats

European journal of pharmacology, 2021-11, Vol.910, p.174465-174465, Article 174465

2021

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Fluoxetine administration in juvenile overfed rats improves hypothalamic mitochondrial respiration and REDOX status and induces mitochondrial biogenesis transcriptional expression

European journal of pharmacology, 2020-08, Vol.881, p.173200-173200, Article 173200

2020

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Crocin ameliorates chronic obstructive pulmonary disease-induced depression via PI3K/Akt mediated suppression of inflammation

European journal of pharmacology, 2019-11, Vol.862, p.172640, Article 172640

2019

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Neurobehavioral effects of liraglutide and sitagliptin in experimental models

European journal of pharmacology, 2016-03, Vol.774, p.64-70

2016

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ACSL family: The regulatory mechanisms and therapeutic implications in cancer

European journal of pharmacology, 2021-10, Vol.909, p.174397, Article 174397

2021

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Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues

European journal of pharmacology, 2015-07, Vol.759, p.253-264

2015

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Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression

European journal of pharmacology, 2021-10, Vol.908, p.174384, Article 174384

2021

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Differential behavioral functioning in the offspring of rats with high vs. low self-administration of the opioid agonist remifentanil

European journal of pharmacology, 2021-10, Vol.909, p.174407-174407, Article 174407

2021

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Animal models of Multiple Sclerosis

European journal of pharmacology, 2015-07, Vol.759, p.182-191

2015

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Animal models for osteoporosis

European journal of pharmacology, 2015-07, Vol.759, p.287-294

Komori, Toshihisa

2015

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Pathogenesis of diabetic neuropathy: Focus on neurovascular mechanisms

European journal of pharmacology, 2013-11, Vol.719 (1-3), p.180-186

2013

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The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals

Animal models of atherosclerosis

Resveratrol modulates Toxoplasma gondii infection induced liver injury by intervening in the HMGB1/TLR4/NF-κB signaling pathway

Rodent models for human diseases

The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease

Ponatinib-induced ischemic stroke in larval zebrafish for drug screening

Macrophage M1/M2 polarization

Supplementation of taurine improves ionic homeostasis and mitochondrial function in the rats exhibiting post-traumatic stress disorder-like symptoms

Preclinical experimental stress studies: Protocols, assessment and comparison

Dopamine-neurotransmission and nociception in zebrafish: An anti-nociceptive role of dopamine receptor drd2a

Experimental models of Parkinson's disease: Challenges and Opportunities

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer's disease

The olfactory bulbectomy model in mice and rat: One story or two tails?

The effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder

Dose-dependent opposite effects of nortriptyline on affective-like behavior in adolescent rats: Comparison with adult rats

Fluoxetine administration in juvenile overfed rats improves hypothalamic mitochondrial respiration and REDOX status and induces mitochondrial biogenesis transcriptional expression

Crocin ameliorates chronic obstructive pulmonary disease-induced depression via PI3K/Akt mediated suppression of inflammation

Neurobehavioral effects of liraglutide and sitagliptin in experimental models

ACSL family: The regulatory mechanisms and therapeutic implications in cancer

Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues

Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression

Differential behavioral functioning in the offspring of rats with high vs. low self-administration of the opioid agonist remifentanil

Animal models of Multiple Sclerosis

Animal models for osteoporosis

Pathogenesis of diabetic neuropathy: Focus on neurovascular mechanisms

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