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Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

JNCI : Journal of the National Cancer Institute, 2001-05, Vol.93 (9), p.691-699

2001

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High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints

Cancer research (Chicago, Ill.), 2000-04, Vol.60 (7), p.1949-1960

2000

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Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma

Journal of medical genetics, 2003-04, Vol.40 (4), p.257-261

2003

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Silencing of the VHL Tumor-Suppressor Gene by DNA Methylation in Renal Carcinoma

Proceedings of the National Academy of Sciences - PNAS, 1994-10, Vol.91 (21), p.9700-9704

1994

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Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer

JAMA : the journal of the American Medical Association, 1995-02, Vol.273 (7), p.564

1995

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STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker

Journal of medical genetics, 2005-07, Vol.42 (7), p.565-576

2005

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Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours

The Journal of pathology, 2008, Vol.214 (1), p.46-57

2008

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Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter

Journal of medical genetics, 2002-07, Vol.39 (7), p.463-472

2002

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Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene

Oncogene, 1998-06, Vol.16 (24), p.3151-3157

1998

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Human Semaphorins A(V) and IV Reside in the 3p21.3 Small Cell Lung Cancer Deletion Region and Demonstrate Distinct Expression Patterns

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (9), p.4120-4125

1996

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Cellular proteins that bind the von Hippel-Lindau disease gene product : mapping of binding domains and the effect of missense mutations

Cancer research (Chicago, Ill.), 1995-10, Vol.55 (20), p.4544-4548

1995

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Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3 : Progress toward the isolation of a lung cancer TSG

Cancer research (Chicago, Ill.), 1996-04, Vol.56 (7), p.1487-1492

1996

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Distinct Hypermethylation Patterns Occur at Altered Chromosome Loci in Human Lung and Colon Cancer

Proceedings of the National Academy of Sciences - PNAS, 1992-03, Vol.89 (5), p.1929-1933

1992

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Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

Science (American Association for the Advancement of Science), 1987-02, Vol.235 (4791), p.877-880

1987

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Constitutional von Hippel-Lindau (VHL) gene deletions detected in VHL families by fluorescence in situ hybridization

Cancer research (Chicago, Ill.), 1999-11, Vol.59 (21), p.5560-5564

1999

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Candidate Tumor Suppressor HYAL2 is a Glycosylphosphatidylinositol (GPI)-Anchored Cell-Surface Receptor for Jaagsiekte Sheep Retrovirus, the Envelope Protein of Which Mediates Oncogenic Transformation

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (8), p.4443-4448

2001

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Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours

Oncogene, 2001-03, Vol.20 (12), p.1509-1518

2001

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Inhibition of Lung Cancer Cell Growth and Induction of Apoptosis after Reexpression of 3p21.3 Candidate Tumor Suppressor Gene SEMA3B

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13954-13959

2001

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Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer

Cancer research (Chicago, Ill.), 2001-12, Vol.61 (24), p.8924-8929

2001

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Deletion of two separate regions on chromosome 3p in breast cancers

Cancer research (Chicago, Ill.), 1994-06, Vol.54 (11), p.3021-3024

1994

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Down-Regulation of Transmembrane Carbonic Anhydrases in Renal Cell Carcinoma Cell Lines by Wild-Type von Hippel-Lindau Transgenes

Proceedings of the National Academy of Sciences - PNAS, 1998-10, Vol.95 (21), p.12596-12601

1998

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Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines

Oncogene, 1994-06, Vol.9 (6), p.1599-1604

1994

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Autoimmunity, spontaneous tumourigenesis, and IL-15 insufficiency in mice with a targeted disruption of the tumour suppressor gene FusI

The Journal of pathology, 2007-04, Vol.211 (5), p.591-601

2007

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Molecular analysis of genetic changes in the origin and development of renal cell carcinoma

Cancer research (Chicago, Ill.), 1991-02, Vol.51 (4), p.1071-1077

1991

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Gene structure of the human MET proto-oncogene

Oncogene, 1997-09, Vol.15 (13), p.1583-1586

1997

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Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints

Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma

Silencing of the VHL Tumor-Suppressor Gene by DNA Methylation in Renal Carcinoma

Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer

STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker

Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours

Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter

Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene

Human Semaphorins A(V) and IV Reside in the 3p21.3 Small Cell Lung Cancer Deletion Region and Demonstrate Distinct Expression Patterns

Cellular proteins that bind the von Hippel-Lindau disease gene product : mapping of binding domains and the effect of missense mutations

Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3 : Progress toward the isolation of a lung cancer TSG

Distinct Hypermethylation Patterns Occur at Altered Chromosome Loci in Human Lung and Colon Cancer

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

Constitutional von Hippel-Lindau (VHL) gene deletions detected in VHL families by fluorescence in situ hybridization

Candidate Tumor Suppressor HYAL2 is a Glycosylphosphatidylinositol (GPI)-Anchored Cell-Surface Receptor for Jaagsiekte Sheep Retrovirus, the Envelope Protein of Which Mediates Oncogenic Transformation

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours

Inhibition of Lung Cancer Cell Growth and Induction of Apoptosis after Reexpression of 3p21.3 Candidate Tumor Suppressor Gene SEMA3B

Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer

Deletion of two separate regions on chromosome 3p in breast cancers

Down-Regulation of Transmembrane Carbonic Anhydrases in Renal Cell Carcinoma Cell Lines by Wild-Type von Hippel-Lindau Transgenes

Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines

Autoimmunity, spontaneous tumourigenesis, and IL-15 insufficiency in mice with a targeted disruption of the tumour suppressor gene FusI

Molecular analysis of genetic changes in the origin and development of renal cell carcinoma

Gene structure of the human MET proto-oncogene

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