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Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Journal of thrombosis and haemostasis, 2010-03, Vol.8 (3), p.613-615

2010

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Effects of Clopidogrel and Aspirin on Platelet Aggregation, Thromboxane Production, and Serotonin Secretion in Horses

Journal of veterinary internal medicine, 2011, Vol.25 (1), p.116-122

2011

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Pharmacokinetic/pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation

Journal of veterinary pharmacology and therapeutics, 2012-02, Vol.35 (1), p.19-32

2012

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Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses

Journal of veterinary pharmacology and therapeutics, 2015-06, Vol.38 (3), p.249-256

2015

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Biological effects of aspirin and clopidogrel in a randomized cross‐over study in 96 healthy volunteers

Journal of thrombosis and haemostasis, 2006-04, Vol.4 (4), p.813-819

2006

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Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease?

Journal of thrombosis and haemostasis, 2015-06, Vol.13 (6), p.920-930

2015

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Pharmacokinetics and effects on thromboxane B2 production following intravenous administration of flunixin meglumine to exercised thoroughbred horses

Journal of veterinary pharmacology and therapeutics, 2015-08, Vol.38 (4), p.313-320

2015

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Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization

British journal of pharmacology, 2007-09, Vol.152 (1), p.73-82

2007

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Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase‐2

British journal of pharmacology, 2005-02, Vol.144 (4), p.538-550

2005

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Comparative Impact on Prostanoid Biosynthesis of Celecoxib and the Novel Nonsteroidal Anti-Inflammatory Drug CG100649

Clinical pharmacology and therapeutics, 2012-06, Vol.91 (6), p.986-993

2012

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Serum Thromboxane B2 Compared to Five Other Platelet Function Tests for the Evaluation of Aspirin Effect in Stable Cardiovascular Disease

Heart, lung & circulation, 2010-04, Vol.19 (4), p.234-242

2010

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Lumiracoxib Does Not Affect the Ex Vivo Antiplatelet Aggregation Activity of Low-Dose Aspirin in Healthy Subjects

Journal of clinical pharmacology, 2005-10, Vol.45 (10), p.1172-1178

2005

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NCX4016 (NO‐Aspirin) has multiple inhibitory effects in LPS‐stimulated human monocytes

British journal of pharmacology, 2001-10, Vol.134 (4), p.905-911

2001

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NCX4016 (NO‐aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs

British journal of pharmacology, 2002-04, Vol.135 (8), p.1882-1888

2002

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Biomarkers of free radical injury during spinal cord ischemia

FEBS letters, 2001-11, Vol.508 (1), p.36-38

2001

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Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse

BioFactors (Oxford), 2006, Vol.28 (1), p.21-31

2006

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Stimulation of bradykinin B2‐receptors on endothelial cells induces relaxation and contraction in porcine basilar artery in vitro

British journal of pharmacology, 1999-09, Vol.128 (1), p.241-247

1999

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Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation

Journal of leukocyte biology, 2001-04, Vol.69 (4), p.631

2001

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Zileuton, a 5‐lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma

American journal of hematology, 2003-09, Vol.74 (1), p.23-25

2003

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Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells

Journal of leukocyte biology, 1993-02, Vol.53 (2), p.165-172

1993

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Lumiracoxib: Pharmacokinetic and Pharmacodynamic Profile When Coadministered with Fluconazole in Healthy Subjects

Journal of clinical pharmacology, 2004-02, Vol.44 (2), p.193-199

2004

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Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy

Transfusion (Philadelphia, Pa.), 2002-09, Vol.42 (9), p.1206-1216

2002

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Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling

Equine veterinary journal, 1995-07, Vol.27 (4), p.247-256

1995

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Effect of some cyclooxygenase inhibitors on the increase in guanosine 3′:5′‐cyclic monophosphate induced by NO‐donors in human whole platelets

British journal of pharmacology, 1998-04, Vol.123 (7), p.1457-1463

1998

Volltextzugriff (PDF)

Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric‐oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats

British journal of pharmacology, 1993-06, Vol.109 (2), p.322-329

1993

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1 – 25 von 69

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ThemaThromboxane B2 - Analogs & Derivatives

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Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Effects of Clopidogrel and Aspirin on Platelet Aggregation, Thromboxane Production, and Serotonin Secretion in Horses

Pharmacokinetic/pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation

Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses

Biological effects of aspirin and clopidogrel in a randomized cross‐over study in 96 healthy volunteers

Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease?

Pharmacokinetics and effects on thromboxane B2 production following intravenous administration of flunixin meglumine to exercised thoroughbred horses

Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization

Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase‐2

Comparative Impact on Prostanoid Biosynthesis of Celecoxib and the Novel Nonsteroidal Anti-Inflammatory Drug CG100649

Serum Thromboxane B2 Compared to Five Other Platelet Function Tests for the Evaluation of Aspirin Effect in Stable Cardiovascular Disease

Lumiracoxib Does Not Affect the Ex Vivo Antiplatelet Aggregation Activity of Low-Dose Aspirin in Healthy Subjects

NCX4016 (NO‐Aspirin) has multiple inhibitory effects in LPS‐stimulated human monocytes

NCX4016 (NO‐aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs

Biomarkers of free radical injury during spinal cord ischemia

Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse

Stimulation of bradykinin B2‐receptors on endothelial cells induces relaxation and contraction in porcine basilar artery in vitro

Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation

Zileuton, a 5‐lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma

Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells

Lumiracoxib: Pharmacokinetic and Pharmacodynamic Profile When Coadministered with Fluconazole in Healthy Subjects

Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy

Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling

Effect of some cyclooxygenase inhibitors on the increase in guanosine 3′:5′‐cyclic monophosphate induced by NO‐donors in human whole platelets

Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric‐oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats

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