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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Journal of the American Chemical Society, 2020-09, Vol.142 (38), p.16240-16253

2020

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Anti-Inflammatory Effect of Anti-TNF‑α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model

Biomacromolecules, 2017-08, Vol.18 (8), p.2379-2388

2017

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Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Journal of organic chemistry, 2023-11, Vol.88 (21), p.15168-15175

2023

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Efficacy, biodistribution and safety comparison of chemically modified antisense oligonucleotides in the retina

Nucleic acids research, 2024-09, Vol.52 (17), p.10447-10463

2024

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Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8471-8484

2020

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Structure-Activity Relationship of Antibody-Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody-Phosphorodiamidate Morpholino Oligomer Conjugates for Drug Development

Journal of medicinal chemistry, 2024-09, Vol.67 (17), p.14868-14884

2024

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Polyethylene-Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes

ACS nano, 2014-12, Vol.8 (12), p.12280-12291

2014

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Tightly linked morpholino-nucleoside chimeras: new, compact cationic oligonucleotide analogues

Organic & biomolecular chemistry, 2021-10, Vol.19 (4), p.8711-8721

2021

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Molybdenum disulfide field-effect transistor biosensor for ultrasensitive detection of DNA by employing morpholino as probe

Biosensors & bioelectronics, 2018-07, Vol.110, p.71-77

2018

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Conditional gene knockdowns in sea urchins using caged morpholinos

Developmental biology, 2021-07, Vol.475, p.21-29

2021

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Peptide-Conjugated PMOs for the Treatment of Myotonic Dystrophy

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2587, p.209

2023

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Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

Angewandte Chemie International Edition, 2014-09, Vol.53 (38), p.10114-10118

International ed. in English, 2014

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Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers

Antimicrobial agents and chemotherapy, 2017-04, Vol.61 (4)

2017

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Combinatorial control of gene function with wavelength-selective caged morpholinos

Methods in enzymology, 2019, Vol.624, p.69-88

2019

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Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Nucleic acids research, 2024-04, Vol.52 (6), p.2836-2847

2024

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Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers

Journal of antimicrobial chemotherapy, 2021-01, Vol.76 (2), p.413-417

2021

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Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Journal of the American Chemical Society, 2016-12, Vol.138 (48), p.15663-15672

2016

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C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

Organic & biomolecular chemistry, 2023-02, Vol.21 (6), p.1242-1253

2023

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Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs

Nucleic acid therapeutics, 2018-06, Vol.28 (3), p.178

2018

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Sequencing of Phosphorodiamidate Morpholino Oligomers by Hydrophilic Interaction Chromatography Coupled to Tandem Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2024-10, Vol.35 (10), p.2490-2498

2024

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Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex

Chemical communications (Cambridge, England), 2023-05, Vol.59 (42), p.6347-635

2023

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Invention and Early History of Morpholinos: From Pipe Dream to Practical Products

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1565, p.1

Summerton, James E

2017

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A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice

Human gene therapy, 2013-03, Vol.24 (3), p.331

2013

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Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

Journal of the American Chemical Society, 2014-07, Vol.136 (26), p.9252-9255

2014

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A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome

Nature medicine, 2021-03, Vol.27 (3), p.536-545

2021

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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Anti-Inflammatory Effect of Anti-TNF‑α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model

Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Efficacy, biodistribution and safety comparison of chemically modified antisense oligonucleotides in the retina

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides

Structure-Activity Relationship of Antibody-Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody-Phosphorodiamidate Morpholino Oligomer Conjugates for Drug Development

Polyethylene-Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes

Tightly linked morpholino-nucleoside chimeras: new, compact cationic oligonucleotide analogues

Molybdenum disulfide field-effect transistor biosensor for ultrasensitive detection of DNA by employing morpholino as probe

Conditional gene knockdowns in sea urchins using caged morpholinos

Peptide-Conjugated PMOs for the Treatment of Myotonic Dystrophy

Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers

Combinatorial control of gene function with wavelength-selective caged morpholinos

Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs

Sequencing of Phosphorodiamidate Morpholino Oligomers by Hydrophilic Interaction Chromatography Coupled to Tandem Mass Spectrometry

Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex

Invention and Early History of Morpholinos: From Pipe Dream to Practical Products

A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice

Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome

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