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Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion

Nature immunology, 2020-12, Vol.21 (12), p.1540-1551

2020

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Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity

Nature immunology, 2021-11, Vol.22 (11), p.1403-1415

2021

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Context‐specific roles of diphthamide deficiency in hepatocellular carcinogenesis

The Journal of pathology, 2022-10, Vol.258 (2), p.149-163

2022

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A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking units

Chemical communications (Cambridge, England), 2018, Vol.54 (59), p.8218-8221

2018

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Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome

Human molecular genetics, 2014-11, Vol.23 (21), p.5579-5596

2014

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A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

Disease models & mechanisms, 2020-07, Vol.13 (7)

2020

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Metabolic and epigenetic regulation of T-cell exhaustion

Nature metabolism, 2020-10, Vol.2 (10), p.1001-1012

2020

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1019 Dysfunctional mitochondria promotes T cell exhaustion and DNA damage responses in CD8+ T cells

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1127-A1127

2023

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Regulating the Golgi apparatus by co-delivery of a COX-2 inhibitor and Brefeldin A for suppression of tumor metastasis

Biomaterials science, 2018-08, Vol.6 (8), p.2144-2155

2018

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Metabolic programs tailor T cell immunity in viral infection, cancer, and aging

Cell metabolism, 2022-03, Vol.34 (3), p.378-395

2022

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836 A novel PD-L1 antibody-IL10 fusion protein, PTL011, exhibits synergized therapeutic effect in hepatocellular carcinoma mouse model

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A934-A934

2023

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1401 PLT012, a monoclonal antibody targeting CD36, unleashes anti-tumor immunity via metabolic reprogramming in tumor microenvironment

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1559-A1559

2023

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514 Disturbed Mitochondrial Dynamics Rewire the Epigenetic Program for CD8+ TIL Exhaustion

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A550-A550

2020

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Immunoediting instructs tumor metabolic reprogramming to support immune evasion

Cell metabolism, 2023-01, Vol.35 (1), p.118-133.e7

2023

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Dex-Aco coating simultaneously increase the biocompatibility and transfection efficiency of cationic polymeric gene vectors

Journal of controlled release, 2019-06, Vol.303, p.253-262

2019

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Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

The Journal of experimental medicine, 2021-02, Vol.218 (2)

2021

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The Wilms’ tumor suppressor Wt1 regulates Coronin 1B expression in the epicardium

Experimental cell research, 2013-06, Vol.319 (10), p.1365-1381

2013

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Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Nature aging, 2023-09, Vol.3 (9), p.1057-1066

2023

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Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8 + T cell formation

Science immunology, 2023-09, Vol.8 (87)

2023

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Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4 + T cells

Science advances, 2020-07, Vol.6 (27), p.eaaz7809-eaaz7809

2020

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β-catenin activation drives thymoma initiation and progression in mice

Oncotarget, 2015-06, Vol.6 (16), p.13978-13993

2015

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Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ

Blood, 2019-11, Vol.134 (Supplement_1), p.250-250

2019

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A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking unitsElectronic supplementary information (ESI) available: Detailed experimental methods and additional data. See DOI: 10.1039/c8cc04363a

2018-07

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Abstract 2370: Revitalizing anti-tumor immunity through PLT012 monoclonal antibody, targeting CD36 for metabolic rewiring in the tumor microenvironment

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.2370-2370

2024

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Layer‐by‐layer self‐assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla

Journal of biomedical materials research. Part A, 2021-02, Vol.109 (2), p.207-218

2021

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Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion

Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity

Context‐specific roles of diphthamide deficiency in hepatocellular carcinogenesis

A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking units

Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome

A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

Metabolic and epigenetic regulation of T-cell exhaustion

1019 Dysfunctional mitochondria promotes T cell exhaustion and DNA damage responses in CD8+ T cells

Regulating the Golgi apparatus by co-delivery of a COX-2 inhibitor and Brefeldin A for suppression of tumor metastasis

Metabolic programs tailor T cell immunity in viral infection, cancer, and aging

836 A novel PD-L1 antibody-IL10 fusion protein, PTL011, exhibits synergized therapeutic effect in hepatocellular carcinoma mouse model

1401 PLT012, a monoclonal antibody targeting CD36, unleashes anti-tumor immunity via metabolic reprogramming in tumor microenvironment

514 Disturbed Mitochondrial Dynamics Rewire the Epigenetic Program for CD8+ TIL Exhaustion

Immunoediting instructs tumor metabolic reprogramming to support immune evasion

Dex-Aco coating simultaneously increase the biocompatibility and transfection efficiency of cationic polymeric gene vectors

Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

The Wilms’ tumor suppressor Wt1 regulates Coronin 1B expression in the epicardium

Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8 + T cell formation

Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4 + T cells

β-catenin activation drives thymoma initiation and progression in mice

Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ

A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking unitsElectronic supplementary information (ESI) available: Detailed experimental methods and additional data. See DOI: 10.1039/c8cc04363a

Abstract 2370: Revitalizing anti-tumor immunity through PLT012 monoclonal antibody, targeting CD36 for metabolic rewiring in the tumor microenvironment

Layer‐by‐layer self‐assembly polyelectrolytes loaded with cyclic adenosine monophosphate enhances the osteo/odontogenic differentiation of stem cells from apical papilla

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