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Molecular mechanism and function of CD40/CD40L engagement in the immune system

Immunological reviews, 2009-05, Vol.229 (1), p.152-172

2009

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Tryptophan hydroxylase-1 regulates immune tolerance and inflammation

The Journal of experimental medicine, 2012-10, Vol.209 (11), p.2127-2135

2012

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CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy

The Journal of immunology (1950), 2017-12, Vol.199 (12), p.4110-4123

2017

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Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice

Cancer Immunology, Immunotherapy, 2022-01, Vol.71 (1), p.97-109

2022

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Mast cells impair the development of protective anti-tumor immunity

Cancer Immunology, Immunotherapy, 2012-12, Vol.61 (12), p.2273-2282

2012

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CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways

Immuno, 2023-09, Vol.3 (3), p.273-288

2023

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550 An Axl-targeting monoclonal antibody that inhibits Axl activity and potently stimulates the innate immune response

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A587-A587

2020

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VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

The Journal of experimental medicine, 2011-03, Vol.208 (3), p.577-592

2011

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Dual targeting of mast cells and TSLP with a bispecific antibody

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.246-246.07

2023

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Abstract 1865: Simultaneous de-repression of innate and adaptive immune responses through dual targeting of ILT4 and PD(L)-1 with bispecific antibodies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1865-1865

2021

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Abstract 4949: Combined immunochemotherapy for poor prognosis breast cancer

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4949-4949

2013

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Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy

Cancer Immunology, Immunotherapy, 2020-10, Vol.69 (10), p.2125-2137

2020

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Abstract 3664: CDX-1402, a dendritic cell targeted fusion protein designed to elicit immunity to mesothelin and HER2 expressing tumors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3664-3664

2017

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Abstract 2392: CDX-527: A novel bispecific immune-modulating antibody targeting CD27 and PD-L1

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2392-2392

2019

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Abstract 1555: Monoclonal antibodies targeting the TAM family of receptor tyrosine kinases

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1555-1555

2019

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Abstract 3217: Preclinical evaluation of the recombinant dendritic cell growth factor CDX-301 (Flt3L), and AST-008, a TLR9 agonist SNA

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3217-3217

2019

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CDX-1140, a Novel Agonist CD40 Antibody with Potent Anti-Lymphoma Activity

Blood, 2016-12, Vol.128 (22), p.1848-1848

2016

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Abstract 3816: Efficacy of CDX-1140, an agonist CD40 antibody, in preclinical tumor models

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3816-3816

2018

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Abstract 253: Synergistic antitumor activity of PD-1 signaling blockade and CD27 costimulation correlates with enhanced ratio of effector to regulatory T cells at the tumor site

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.253-253

2015

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Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines

Blood, 2008-03, Vol.111 (6), p.3116-3125

2008

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Dendritic Cells Require the NF-κB2 Pathway for Cross-Presentation of Soluble Antigens

The Journal of immunology (1950), 2008-07, Vol.181 (1), p.354-363

2008

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Molecular mechanism and function of CD40/CD40L engagement in the immune system: Mechanisms of Costimulation

Immunological reviews, 2009, Vol.229, p.152-172

2009

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The mechanism of anti-tumor immunity induced by varlilumab, a CD27 agonist mAb, is model dependent

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.P188-P188

2015

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Bridging the adaptive and innate immune system: A study on mast cells and the regulation of tumor immunity

Wasiuk, Anna

2010

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Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens

The Journal of immunology (1950), 2008-07, Vol.181 (1), p.354-363

2008

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Molecular mechanism and function of CD40/CD40L engagement in the immune system

Tryptophan hydroxylase-1 regulates immune tolerance and inflammation

CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy

Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice

Mast cells impair the development of protective anti-tumor immunity

CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways

550 An Axl-targeting monoclonal antibody that inhibits Axl activity and potently stimulates the innate immune response

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

Dual targeting of mast cells and TSLP with a bispecific antibody

Abstract 1865: Simultaneous de-repression of innate and adaptive immune responses through dual targeting of ILT4 and PD(L)-1 with bispecific antibodies

Abstract 4949: Combined immunochemotherapy for poor prognosis breast cancer

Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy

Abstract 3664: CDX-1402, a dendritic cell targeted fusion protein designed to elicit immunity to mesothelin and HER2 expressing tumors

Abstract 2392: CDX-527: A novel bispecific immune-modulating antibody targeting CD27 and PD-L1

Abstract 1555: Monoclonal antibodies targeting the TAM family of receptor tyrosine kinases

Abstract 3217: Preclinical evaluation of the recombinant dendritic cell growth factor CDX-301 (Flt3L), and AST-008, a TLR9 agonist SNA

CDX-1140, a Novel Agonist CD40 Antibody with Potent Anti-Lymphoma Activity

Abstract 3816: Efficacy of CDX-1140, an agonist CD40 antibody, in preclinical tumor models

Abstract 253: Synergistic antitumor activity of PD-1 signaling blockade and CD27 costimulation correlates with enhanced ratio of effector to regulatory T cells at the tumor site

Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines

Dendritic Cells Require the NF-κB2 Pathway for Cross-Presentation of Soluble Antigens

Molecular mechanism and function of CD40/CD40L engagement in the immune system: Mechanisms of Costimulation

The mechanism of anti-tumor immunity induced by varlilumab, a CD27 agonist mAb, is model dependent

Bridging the adaptive and innate immune system: A study on mast cells and the regulation of tumor immunity

Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens

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