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Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis

Molecular psychiatry, 2020-11, Vol.25 (11), p.2685-2694

2020

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Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Molecular psychiatry, 2015-12, Vol.20 (12), p.1499-1507

2015

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Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Journal of lipid research, 2022-08, Vol.63 (8), p.100249, Article 100249

2022

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Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment

Molecular psychiatry, 2019-04, Vol.24 (4), p.491-500

2019

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Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

The Journal of neuroscience, 2007-10, Vol.27 (40), p.10695-10702

2007

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Immune system gene dysregulation in autism and schizophrenia

Developmental neurobiology (Hoboken, N.J.), 2012-10, Vol.72 (10), p.1277-1287

2012

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Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury

Pediatric research, 2022-01, Vol.91 (1), p.92-100

2022

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Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Journal of lipid research, 2017-11, Vol.58 (11), p.2139-2146

2017

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Trazodone effects on developing brain

Translational psychiatry, 2021-02, Vol.11 (1), p.85-9, Article 85

2021

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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Annals of neurology, 2006-03, Vol.59 (3), p.478-489

2006

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The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.1102-1115

2016

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Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Toxicology and applied pharmacology, 2018-06, Vol.349, p.21-28

2018

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Medication effects on developmental sterol biosynthesis

Molecular psychiatry, 2022-01, Vol.27 (1), p.490-501

2022

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Disruption of cerebral cortex MET signaling in autism spectrum disorder

Annals of neurology, 2007-09, Vol.62 (3), p.243-250

2007

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Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Journal of lipid research, 2013-04, Vol.54 (4), p.1135-1143

2013

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Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Journal of neurodevelopmental disorders, 2018-06, Vol.10 (1), p.18-18, Article 18

2018

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Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

The Journal of neuroscience, 2002-04, Vol.22 (7), p.2718-2729

2002

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Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Trends in Neurosciences, 2001-08, Vol.24 (8), p.479-486

2001

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Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Nature communications, 2016-09, Vol.7 (1), p.12743-12743, Article 12743

2016

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Synaptic changes in the brain of subjects with schizophrenia

International journal of developmental neuroscience, 2011-05, Vol.29 (3), p.305-309

2011

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Cholesterol Biosynthesis and Uptake in Developing Neurons

ACS chemical neuroscience, 2019-08, Vol.10 (8), p.3671-3681

2019

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Neurodevelopment, GABA system dysfunction, and schizophrenia

Neuropsychopharmacology (New York, N.Y.), 2015-01, Vol.40 (1), p.190-206

2015

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Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24

ACS chemical neuroscience, 2020-05, Vol.11 (10), p.1413-1423

2020

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Progress in the use of microarray technology to study the neurobiology of disease

Nature neuroscience, 2004-05, Vol.7 (5), p.434-439

2004

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Prescription Medications Alter Neuronal and Glial Cholesterol Synthesis

ACS chemical neuroscience, 2021-02, Vol.12 (4), p.735-745

2021

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Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis

Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Immune system gene dysregulation in autism and schizophrenia

Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury

Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Trazodone effects on developing brain

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Medication effects on developmental sterol biosynthesis

Disruption of cerebral cortex MET signaling in autism spectrum disorder

Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Synaptic changes in the brain of subjects with schizophrenia

Cholesterol Biosynthesis and Uptake in Developing Neurons

Neurodevelopment, GABA system dysfunction, and schizophrenia

Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24

Progress in the use of microarray technology to study the neurobiology of disease

Prescription Medications Alter Neuronal and Glial Cholesterol Synthesis

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